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" Federally funded cancer research will continue to decline in real terms.

Advocates were hopeful that the National Institutes of Health (NIH) and National

Cancer Institute (NCI) would receive significant budget increases after being

flat-funded for the better part of the last decade. The Leukemia & Lymphoma

Society (LLS) and the rest of the cancer advocacy community have advocated for

increases of $4.2 billion for the NIH and $691 million for the NCI; bringing

their overall FY 2011 budgets to $35 billion and $5.7 billion, respectively.

While there is still a chance that funding for cancer research could be

increased in either an extended continuing resolution or a budget passed once

Congress returns to the Hill, continuing budget pressures make the prospect

increasingly unlikely.

" In addition to NIH and NCI, the continuing resolution also maintained spending

levels for other programs important to blood cancer patients. Among them, the

Geraldine Ferraro Blood Cancer Education Program, housed at the Centers for

Disease Control and Prevention (CDC), which will be funded at its FY 2010 budget

level of $4.67 million. The program had been cut from the Administration's

budget proposal sent to Congress in February and was the subject of appeals to

Congress, so its inclusion in the continuing resolution is a positive outcome

and a credit to blood cancer advocates. "

" In the final days in session before members left for the campaign trail,

Congress took action on several bills that affect blood cancer patients. Both

chambers of Congress passed The Stem Cell Therapeutic and Research

Reauthorization Act of 2010 (H.R.6081 / S.3751) and the bill now moves to

President Barack Obama's desk to be signed into law. This measure would

reauthorize a previous law that reformed the National Marrow Donor Program

(NMDP), which operates a registry to find unrelated donors for patients who need

a bone marrow or cord blood transplant. "

LLS Advocacy Update - go to www.LLS.org

______________________

Vitamin D May Help Relieve Asthma October 19, 2010

" For years, medical experts have speculated that asthma may be linked to a

deficiency of vitamin D. Though debate continues over how much vitamin D is

enough, experts now believe they have uncovered an association between asthma

and low levels of the " sunshine vitamin, " so called because our bodies can

manufacture vitamin D when exposed to sunlight.

" To better understand the relationship between vitamin D and asthma, researchers

combed through asthma-related scientific articles published between 1950 and

2009. They discovered that asthma is more common among people with obesity,

African Americans and people living in Westernized countries—the same groups

that also have higher rates of vitamin D deficiency. "

http://tinyurl.com/2g2vj4f

__________________

This was the treatment in 1953

http://tinyurl.com/2dw8kth

____________________

FRIDAY, Feb. 20 (HealthDay News) -- " U.S. researchers say they've spotted a

mechanism by which chronic myeloid leukemia (CML) progresses into a deadlier

stage. The finding may improve patient outcomes, they said. The researchers

found that when a molecular off-switch called glycogen synthase kinase (GSK) 3

beta becomes faulty in chronic stage CML cells, it fails to turn off another

protein called beta-catenin. This enables pre-leukemia stem cells to develop

into leukemia stem cells and increase their numbers, leading to the more

dangerous " blast crisis " state of CML.

" If we can predict when a patient is moving from the chronic phase in CML to the

blast crisis stage, then we can hopefully intervene before it's too late, " study

co-leader Dr. Catriona H.M. son, an assistant professor of medicine at the

University of California, San Diego (UCSD) School of Medicine and director for

Stem Cell Research at the s UCSD Cancer Center, said in a university news

release. "

http://tinyurl.com/2eh6d9s

_____________________

" It is estimated that 4,870 men and women (2,800 men and 2,070 women) will be

diagnosed with and 440 men and women will die of chronic myeloid leukemia in

2010.

(http://seer.cancer.gov/csr/ 1975_2007/results_single/ sect_01_ta

Table.01.pdf).

The following information is based on NCI’s SEER Cancer Statistics Review

Chronic Myeloid Leukemia Section

(http://seer.cancer.gov/csr/ 1975_2007/results_merged/ sect_13_leukemia.pdf)

..Use the links on this page to learn more about each statistic type:

a.. Incidence & Mortality, Survival,Lifetime Risk, & References

http://tinyurl.com/26v3a8t

___________________

LIFETIME RISKS: posted to the SEER web site, 2010.Surgical Errors Continue

Despite Protocols (Written by Roni C. Rabin) on 10/15/1

/ / / / / / / / / / / / / / / /

" Despite a requirement that hospitals abide by a standard set of procedures to

prevent surgical mistakes like operating on the wrong patient or the wrong body

part, such errors continue to occur far too often, researchers are reporting.

In the worst case reported, a chest tube was inserted into the wrong lung — the

healthy one — and it collapsed, killing the patient. In other cases, surgeons

removed a healthy ovary, operated on the wrong side of the brain, fused the

wrong vertebrae and did procedures on the wrong eye, knee, foot, elbow and hand.

" Based on rates from 2005-2007, 0.16% of men and women born today will be

diagnosed with chronic myeloid leukemia at some time during their lifetime. This

number can also be expressed as 1 in 635 men and women will be diagnosed with

chronic myeloid leukemia during their lifetime. These statistics are called the

lifetime risk.

" The probability of developing cancer in the course of one's lifespan. Lifetime

risk may also be discussed in terms of the probability of developing or of dying

from cancer. Based on cancer rates from 2005 to 2007, it was estimated that men

had about a 44 percent chance of developing cancer in their lifetimes, while

women had about a 38 percent chance. of developing cancer. Sometimes it is more

useful to look at the probability of developing The chance that a person will

develop cancer in his/her lifetime. chronic myeloid leukemia between two age

groups. For example, 0.05% of men will develop chronic myeloid leukemia between

their 50th and 70th birthdays compared to 0.04% for women. (See Fast Stats for

more detailed statistics, and Probability of Developing and Dying of Cancer for

methodology. "

http://tinyurl.com/2w3cp3c

__________________

Losing Touch With the Patient ( By: PAULINE W. CHEN, M.D., October 21, 2010)

" Several years ago I helped care for a man who had been hospitalized with a

severe infection of the abdominal wall. When his primary doctors discovered that

the bacteria responsible was resistant to most antibiotics, they quickly

isolated him, moving him into a single room with a sign on the door proclaiming

“Contact Precautions” and directing visitors to put on gloves, mask and gown

before entering.

Doctor and Patient

Losing Touch With the Patient

By PAULINE W. CHEN, M.D.

Published: October 21, 2010

a.. Recommend

b.. Twitter

c.. Sign In to E-Mail

d.. Print

e..

Reprints

a.. ShareClose

a.. Linkedin

b.. Digg

c.. Mixx

d.. MySpace

e.. Buzz

f.. Permalink

g..

Several years ago I helped care for a man who had been hospitalized with a

severe infection of the abdominal wall. When his primary doctors discovered that

the bacteria responsible was resistant to most antibiotics, they quickly

isolated him, moving him into a single room with a sign on the door proclaiming

“Contact Precautions” and directing visitors to put on gloves, mask and gown

before entering.

" But garbing up in all those items was not a straightforward exercise. The

gowns, vast swaths of baby-yellow polyester, added an insulating and

sweat-inducing layer. The masks were either so flimsy they fell off easily or so

unyielding they muffled voices and steamed up eyeglasses. And the gloves had

such generous finger pockets that the excess latex inevitably got tangled in the

loops and ties of the gowns and masks or in the dressing materials and bedding

of the patient.

As the weeks wore on, we clinicians found ourselves minimizing our interactions,

designating one team member to suit up and complete the work needed or shouting

out updates and questions to the patient from the sterile safety of the doorway.

" Increasingly isolated in these ways, he began to withdraw from everyone except

his wife. His once daily declarations that he was going to “beat this infection”

became less vocal, dimming to whispers, then disappearing altogether. He stopped

turning to face us when we called out to him, choosing instead to continue

staring blankly at the ceiling. In trying so hard to contain the infection, had

we lost sight of the person? "

http://tinyurl.com/2ds2qnr

___________________

FYI,

Lottie Duthu

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