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Getting into New Trial

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Dear Leah,

I'm glad you mentioned (get my counts down to where I could participate in

the Gleevec high-dose) - your quote. Not everyone who wants to get into a trial

is able to get in for some health reason that the drug company would reject you.

Our friend, Jackie who is at MDACC recuperating from her BMT was not able to get

into the Sprycel trial when the rest of us were in it, because her pulse was too

slow. Your heart is checked over and over to be sure you can withstand the

harshness of the drugs.

I, myself, was rejected twice, but they worked with me and were able to get my

counts to where I was accepted. When I went to MDACC a few weeks ago to get

into the ARiad trial, I would not have at that time been a candidate for the

trial, because one of my counts was not aligned. Since that time, that one

count has come back to the normal range.

A person on dialysis, would not be a good candidate and would probably be

rejected. Once my bun was high and other time my calcium was low. It's almost

like a tryout for a play. It is up to the drug companies who make that

decision, not to the doctors who are conducting the trial. In some cases, they

may intervene on your behalf, however. I felt like when I was accepted into a

trial, it was like a rite of passage.

Happy Wednesday,

Lottie Duthu

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