Re: Re: follow up - CML and atrial fibrillation

[Guest guest]

Giles, what do you mean, it was horrible?  In what way?  I have been on

motoprolol for a couple of years, with no problem, is it the coumadin that was

bad, or the combo.  I took it today for the first time along with a zillion

other meds, so far so good.  Bobby

a ( Bobby ) Doyle, dob 12/17/29

DX 5/1995

Interferon 9 weeks/Hydroxyurea 5 years

02/2000 to 06/2002 Gleevec trial, OHSU

06/2002 Gleevec/Trisenox Trial, OHSU

06/2003 Gleevec/Zarnestra Trial, OHSU

04/2004 Sprycel Trial, MDACC, CCR in 10 months

04/2008 XL228 Trial, U of Mich.

01/2009 PCR 5.69

04/2009 Ariad Trial AP24534

09/2009 PCR 0.01

11/2009 PCR 0.034

02/2010 PCRU

#840 Zavie's Zero Club

From: Gilles <cousineaugilles@...>

Subject: [ ] Re: follow up - CML and atrial fibrillation

Date: Saturday, January 15, 2011, 5:26 PM

 

Hi a,

I was diagnosed atrial fibrillation (FA) at June 2003. In August 2004,

my white blood and platelets started to increase. I took Hydrea and Agrylin. The

doctors thought that I hadessential thrombocytemia (ET). In June 2005, they

found that I had CML and I started Gleevec (400 mg).

In June 2003, I took metoprolol and Coumadin. It was horrible. Now, I

take Monocor (5mg), Rythmol (600 mg) and Coumadin (3.75mg). I am 57 years old.

1% of people over 60 years of age have atrial fibrillation (ref.

http://www.medicinenet.com/atrial_fibrillation/page3.htm).

I hope everything goes well for you

Gilles from Montreal

>

> Hi, well, the good news is, the shortness of breath is not Ariad.  the bad

news is, it is

> atrial fibrillation.  He took me off Hydrochlorathiazide and put me on

coumadin, doubled the Metoprlol, and put me on Lasix daily.  I'll be ship shape

in no time.  But no one has let me know the scan results yet, will have to wait

til Mon.  Lottie, you are right, I AM an old broad and I am just falling to

pieces in front of my own eyes!!  Oh yes, and there is always this to consider,

what caused the A fib?  could it be the Ariad?  Have not talked to Dr. Talpaz

but I am hoping it is certainly  NOT Ariad and I want back on it ASAP.   I am

ticked off with my gastro. doctor, he surely had the results yesterday, the scan

was done early Thurs. 

> That's it for now, Bobby (the next to oldest broad on the site!!!!!)

>

> a ( Bobby ) Doyle, dob 12/17/29

> DX 5/1995

> Interferon 9 weeks/Hydroxyurea 5 years

> 02/2000 to 06/2002 Gleevec trial, OHSU

> 06/2002 Gleevec/Trisenox Trial, OHSU

> 06/2003 Gleevec/Zarnestra Trial, OHSU

> 04/2004 Sprycel Trial, MDACC, CCR in 10 months

> 04/2008 XL228 Trial, U of Mich.

> 01/2009 PCR 5.69

> 04/2009 Ariad Trial AP24534

> 09/2009 PCR 0.01

> 11/2009 PCR 0.034

> 02/2010 PCRU

> #840 Zavie's Zero Club

>

>

>

[Guest guest]

Hi Gilles,

I was wondering about your dose of Coumadin. I don't see a tablet of 3.75

mg, but I do see one of 7.5 mg. Are you splitting one in half?

I use Coumadin for a mechanical heart valve and adjust the dose pretty

often. I was wondering why your weren't taking a 4 mg dose of Coumadin.

Hope all is well with you and that you are maintaining your PCRU status.

Zavie

From: [mailto: ] On Behalf Of Gilles

Sent: January-15-11 5:27 PM

Subject: [ ] Re: follow up - CML and atrial fibrillation

Hi a,

I was diagnosed atrial fibrillation (FA) at June 2003. In August 2004, my

white blood and platelets started to increase. I took Hydrea and Agrylin.

The doctors thought that I hadessential thrombocytemia (ET). In June 2005,

they found that I had CML and I started Gleevec (400 mg).

In June 2003, I took metoprolol and Coumadin. It was horrible. Now, I take

Monocor (5mg), Rythmol (600 mg) and Coumadin (3.75mg). I am 57 years old. 1%

of people over 60 years of age have atrial fibrillation (ref.

http://www.medicinenet.com/atrial_fibrillation/page3.htm).

I hope everything goes well for you

Gilles from Montreal

>

> Hi, well, the good news is, the shortness of breath is not Ariad. the bad

news is, it is

> atrial fibrillation. He took me off Hydrochlorathiazide and put me on

coumadin, doubled the Metoprlol, and put me on Lasix daily. I'll be ship

shape in no time. But no one has let me know the scan results yet, will

have to wait til Mon. Lottie, you are right, I AM an old broad and I am

just falling to pieces in front of my own eyes!! Oh yes, and there is

always this to consider, what caused the A fib? could it be the Ariad?

Have not talked to Dr. Talpaz but I am hoping it is certainly NOT Ariad and

I want back on it ASAP. I am ticked off with my gastro. doctor, he surely

had the results yesterday, the scan was done early Thurs.

> That's it for now, Bobby (the next to oldest broad on the site!!!!!)

>

> a ( Bobby ) Doyle, dob 12/17/29

> DX 5/1995

> Interferon 9 weeks/Hydroxyurea 5 years

> 02/2000 to 06/2002 Gleevec trial, OHSU

> 06/2002 Gleevec/Trisenox Trial, OHSU

> 06/2003 Gleevec/Zarnestra Trial, OHSU

> 04/2004 Sprycel Trial, MDACC, CCR in 10 months

> 04/2008 XL228 Trial, U of Mich.

> 01/2009 PCR 5.69

> 04/2009 Ariad Trial AP24534

> 09/2009 PCR 0.01

> 11/2009 PCR 0.034

> 02/2010 PCRU

> #840 Zavie's Zero Club

>

>

>

[Guest guest]

Thanks for the reply, it is strange how different drugs effect people in so many

different ways.

a ( Bobby ) Doyle, dob 12/17/29

DX 5/1995

Interferon 9 weeks/Hydroxyurea 5 years

02/2000 to 06/2002 Gleevec trial, OHSU

06/2002 Gleevec/Trisenox Trial, OHSU

06/2003 Gleevec/Zarnestra Trial, OHSU

04/2004 Sprycel Trial, MDACC, CCR in 10 months

04/2008 XL228 Trial, U of Mich.

01/2009 PCR 5.69

04/2009 Ariad Trial AP24534

09/2009 PCR 0.01

11/2009 PCR 0.034

02/2010 PCRU

#840 Zavie's Zero Club

From: Gilles <cousineaugilles@...>

Subject: [ ] Re: follow up - CML and atrial fibrillation

Date: Sunday, January 16, 2011, 1:20 AM

 

Hi a,

With Motoprolol, my heart was unstable (varying pulse, the pressure

was not well controlled, many extrasystoles ...) I felt very sick and I had a

lack of energy ... In my case, Monocor is a lot better.

Goodbye,

Gilles

>

> >

>

> > Hi, well, the good news is, the shortness of breath is not Ariad.  the

bad news is, it is

>

> > atrial fibrillation.  He took me off Hydrochlorathiazide and put me on

coumadin, doubled the Metoprlol, and put me on Lasix daily.  I'll be ship

shape in no time.  But no one has let me know the scan results yet, will have

to wait til Mon.  Lottie, you are right, I AM an old broad and I am just

falling to pieces in front of my own eyes!!  Oh yes, and there is always this

to consider, what caused the A fib?  could it be the Ariad?  Have not

talked to Dr. Talpaz but I am hoping it is certainly  NOT Ariad and I want

back on it ASAP.   I am ticked off with my gastro. doctor, he surely had

the results yesterday, the scan was done early Thurs. 

>

> > That's it for now, Bobby (the next to oldest broad on the site!!!!!)

>

> >

>

> > a ( Bobby ) Doyle, dob 12/17/29

>

> > DX 5/1995

>

> > Interferon 9 weeks/Hydroxyurea 5 years

>

> > 02/2000 to 06/2002 Gleevec trial, OHSU

>

> > 06/2002 Gleevec/Trisenox Trial, OHSU

>

> > 06/2003 Gleevec/Zarnestra Trial, OHSU

>

> > 04/2004 Sprycel Trial, MDACC, CCR in 10 months

>

> > 04/2008 XL228 Trial, U of Mich.

>

> > 01/2009 PCR 5.69

>

> > 04/2009 Ariad Trial AP24534

>

> > 09/2009 PCR 0.01

>

> > 11/2009 PCR 0.034

>

> > 02/2010 PCRU

>

> > #840 Zavie's Zero Club

>

> >

>

> >

>

> >