Guest guest Posted February 2, 2011 Report Share Posted February 2, 2011 This is a compilation about Gleevec furnished by the federal government. These were all peer reviewed until 2002 or 2003, about side effects and toxicity. You may want to see if your side effects are listed at the website. Biological half life of Gleevec: Elimination - Approximately 18 and 40 hours, for imatinib and its primary metabolite, respectively. This may apply to those on Warfarin therapy: Because warfarin is metabolized by CYP2C9 and CYP3A4, patients who require anticoagulation should receive low-molecular weight or standard heparin. [Medical Economics Co; Physicians Desk Reference on line version as of July 24, 2003] **PEER REVIEWED** Thrombocytopenia: Grade III-IV thrombocytopenia is common in accelerated phase CML and may be a marker for the inability to achieve cytogenetic response using single agent imatinib mesylate. Disposal Methods: SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. RECYCLE ANY UNUSED PORTION OF THE MATERIAL for its approved use (DOES THAT MEAN TO GIVE IT AWAY?) or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations. http://tinyurl.com/67fonvu FYI, Lottie Duthu Quote Link to comment Share on other sites More sharing options...
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