Re: Low hb, tc and platelet count for CML accelerated phase

[Guest guest]

Hi

sorry i didnt see your name.

can you tell us where is your father living?

There are 2 second generation drugs already approved in mnay countries which are

called Sprycel (Dasatinib) and Tasigna (Nilotinib). Both these drugs are

stronger than Glivec and show good results in patients like your father who

develop resistance to glivec. I dont know if your father can get one of these

drugs but this should be the choice treatment, unless your father is candidate

for a bone marrow transplant.

CML is a 3 stages disease, chronic, accelerated and blast. the treatment during

the advanced phases are more difficult.

with best regards

Giora

[ ] Low hb, tc and platelet count for CML accelerated phase

Hi All,

My Father, aged 52, was detected with blood cancer (CML) in 2002. He was

taking glivec(Imatinib) tablets.

Unfortunately, by 2010, his disease progressed to accelerated phase marked by

reduced hb count and platelet count. He was submitted to one session of

chemotherapy and given blood transfusion. Blood counts were brought to normal

levels and he was brought back home. But, in the past week blood test showed

that hb, tc and platelets was reduced abnormally (hb was 4, platelet was 1000,

tc was 200). He is currently on blood transfusion again.

As the doctors are not revealing much and asking us to wish for a miracle, Can

someone please tell me what condition he is in currently. We are confused as

there was a reduction in TC (WBC) levels too. Did his disease get worse? What

could be the possible treatment options? Is there any chance for him to return

to chronic phase?

Options of bone marrow and stem cell transplant has been ruled out by doctors

due to his weak body and age.

[Guest guest]

Hello

Name here is Skipd.  I have been on infusions of Red Cells (Hgb) and Platelets

for about 3 years now.  My Platelets (Plt) were down on many occasions

to Zero.  On many occasions my Hgb has been down to 80 or less.  I cannot take

any meds for my CML so I just get infusions, My WBC has been down to

less that 1 and my ANC has been down below 2.0. Other than a wee bit tired I

feel ok.  In fact my QOL (quality of life) is pretty good, take wife shopping

and

out to supper.  That is when my ANC is above 5.0 (should be 2000). I would ask

if the Bone Marrow can produce blood and platlets.

I now get infused about twice weekly at the local hospital. 

I am not sure where your located but 52 is not old.  I am over 70.  I think I

would get another opinions if possible.  If not I am sure someone on here

will be able to direct you to someone who has knowledge in CML and Doctor's in

your area.  I would not worry yet, we can live on infusions

what we cannot live without is Love. Hey I have lived my 3 score and 10, even if

I did not have CML, I am sure your dad can as well.

Best of Luck

Skip

DX'ed 33 years ago (34 year coming up)

 

________________________________

From: rishma_raj <rishma_raj@...>

Sent: Sun, February 20, 2011 4:04:49 AM

Subject: [ ] Low hb, tc and platelet count for CML accelerated phase

 

Hi All,

My Father, aged 52, was detected with blood cancer (CML) in 2002. He was taking

glivec(Imatinib) tablets.

Unfortunately, by 2010, his disease progressed to accelerated phase marked by

reduced hb count and platelet count. He was submitted to one session of

chemotherapy and given blood transfusion. Blood counts were brought to normal

levels and he was brought back home. But, in the past week blood test showed

that hb, tc and platelets was reduced abnormally (hb was 4, platelet was 1000,

tc was 200). He is currently on blood transfusion again.

As the doctors are not revealing much and asking us to wish for a miracle, Can

someone please tell me what condition he is in currently. We are confused as

there was a reduction in TC (WBC) levels too. Did his disease get worse? What

could be the possible treatment options? Is there any chance for him to return

to chronic phase?

Options of bone marrow and stem cell transplant has been ruled out by doctors

due to his weak body and age.

[Guest guest]

Hi,

We live in India and these drugs were not suggested by our doctor. He is living

on transfusions and his body is very weak. He has uncontrolled bowels and a very

weak body.

I feel very sad looking at him. Maybe I should ask our doctor for the medicine.

RISHMA RAJ

________________________________

From: giora <giora1@...>

Sent: Sun, 20 February, 2011 10:56:37 PM

Subject: Re: [ ] Low hb, tc and platelet count for CML accelerated phase

Hi

sorry i didnt see your name.

can you tell us where is your father living?

There are 2 second generation drugs already approved in mnay countries which are

called Sprycel (Dasatinib) and Tasigna (Nilotinib). Both these drugs are

stronger than Glivec and show good results in patients like your father who

develop resistance to glivec. I dont know if your father can get one of these

drugs but this should be the choice treatment, unless your father is candidate

for a bone marrow transplant.

CML is a 3 stages disease, chronic, accelerated and blast. the treatment during

the advanced phases are more difficult.

with best regards

Giora

[ ] Low hb, tc and platelet count for CML accelerated phase

Hi All,

My Father, aged 52, was detected with blood cancer (CML) in 2002. He was taking

glivec(Imatinib) tablets.

Unfortunately, by 2010, his disease progressed to accelerated phase marked by

reduced hb count and platelet count. He was submitted to one session of

chemotherapy and given blood transfusion. Blood counts were brought to normal

levels and he was brought back home. But, in the past week blood test showed

that hb, tc and platelets was reduced abnormally (hb was 4, platelet was 1000,

tc was 200). He is currently on blood transfusion again.

As the doctors are not revealing much and asking us to wish for a miracle, Can

someone please tell me what condition he is in currently. We are confused as

there was a reduction in TC (WBC) levels too. Did his disease get worse? What

could be the possible treatment options? Is there any chance for him to return

to chronic phase?

Options of bone marrow and stem cell transplant has been ruled out by doctors

due to his weak body and age.

[Guest guest]

I should add, he is accelerated phase and though he is living on transfusions

but his body is very weak and he cannot move by himself. Uncontrolled bowels is

another issue. We run for O-ve donors everywhere.

RISHMA RAJ

________________________________

From: Skip Duffie <skipd_2002@...>

Sent: Mon, 21 February, 2011 5:27:14 PM

Subject: Re: [ ] Low hb, tc and platelet count for CML accelerated phase

Hello

Name here is Skipd. I have been on infusions of Red Cells (Hgb) and Platelets

for about 3 years now. My Platelets (Plt) were down on many occasions

to Zero. On many occasions my Hgb has been down to 80 or less. I cannot take

any meds for my CML so I just get infusions, My WBC has been down to

less that 1 and my ANC has been down below 2.0. Other than a wee bit tired I

feel ok. In fact my QOL (quality of life) is pretty good, take wife shopping

and

out to supper. That is when my ANC is above 5.0 (should be 2000). I would ask

if the Bone Marrow can produce blood and platlets.

I now get infused about twice weekly at the local hospital.

I am not sure where your located but 52 is not old. I am over 70. I think I

would get another opinions if possible. If not I am sure someone on here

will be able to direct you to someone who has knowledge in CML and Doctor's in

your area. I would not worry yet, we can live on infusions

what we cannot live without is Love. Hey I have lived my 3 score and 10, even if

I did not have CML, I am sure your dad can as well.

Best of Luck

Skip

DX'ed 33 years ago (34 year coming up)

________________________________

From: rishma_raj <rishma_raj@...>

Sent: Sun, February 20, 2011 4:04:49 AM

Subject: [ ] Low hb, tc and platelet count for CML accelerated phase

Hi All,

My Father, aged 52, was detected with blood cancer (CML) in 2002. He was taking

glivec(Imatinib) tablets.

Unfortunately, by 2010, his disease progressed to accelerated phase marked by

reduced hb count and platelet count. He was submitted to one session of

chemotherapy and given blood transfusion. Blood counts were brought to normal

levels and he was brought back home. But, in the past week blood test showed

that hb, tc and platelets was reduced abnormally (hb was 4, platelet was 1000,

tc was 200). He is currently on blood transfusion again.

As the doctors are not revealing much and asking us to wish for a miracle, Can

someone please tell me what condition he is in currently. We are confused as

there was a reduction in TC (WBC) levels too. Did his disease get worse? What

could be the possible treatment options? Is there any chance for him to return

to chronic phase?

Options of bone marrow and stem cell transplant has been ruled out by doctors

due to his weak body and age.