ARIAD And MolecularMD Announce Collaboration for a Companion Diagnostic Test for The T315I BCR-ABL Mutation in Patients With CML

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March 28, 2011 07:35 AM Eastern Daylight Time

ARIAD And MolecularMD Announce Collaboration for a Companion Diagnostic Test

for The T315I BCR-ABL Mutation in Patients With

CML<http://www.businesswire.com/news/home/20110328005408/en/ARIAD-MolecularMD-An\

nounce-Collaboration-Companion-Diagnostic-Test>

<http://www.businesswire.com/news/home/20110328005408/en/ARIAD-MolecularMD-Annou\

nce-Collaboration-Companion-Diagnostic-Test>CAMBRIDGE,

Mass. & PORTLAND, Ore.--(BUSINESS WIRE)--ARIAD

Pharmaceuticals, Inc.

<http://cts.businesswire.com/ct/CT?id=smartlink & url=http%3A%2F%2Fwww.ariad.com%2\

F & esheet=6660914 & lan=en-US & anchor=ARIAD+Pharmaceuticals%2C+Inc.+ & index=1 & md5=0af\

6f3d1c751b2bfb62b2828e389fa23>(NASDAQ:

ARIA) and MolecularMD Corporation today announced an exclusive collaboration

agreement in which MolecularMD will develop and commercialize a companion

diagnostic test to identify the T315I mutation of the BCR-ABL gene in

patients with chronic myeloid leukemia (CML) and Philadelphia positive (Ph+)

acute lymphoblastic leukemia (ALL).

ARIAD is advancing its investigational, pan-BCR-ABL inhibitor, ponatinib, in

the pivotal PACE trial of patients with resistant or intolerant CML and Ph+

ALL, or those with the T315I mutation. MolecularMD has performed BCR-ABL

mutation testing with its standardized and validated sequencing test in

patients enrolled in ARIAD’s earlier Phase 1 trial of ponatinib and now is

cond...

*Read the full news release on BusinessWire.com

*<http://www.businesswire.com/news/home/20110328005408/en/ARIAD-MolecularMD-Anno\

unce-Collaboration-Companion-Diagnostic-Test>

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