Re: Re: Relapse to Beverly

[Guest guest]

and how are you going with sprycel?

From: Beverly Blair

Sent: Wednesday, January 26, 2011 12:55 AM

Subject: Re: [ ] Re: Relapse

Sprycel.

Sent from my iPhone

On Jan 25, 2011, at 1:49 PM, " hey00nanc " <mailto:ncogan%40uoregon.edu> wrote:

>

>

>

> >

> > and now which medicine are you taking? tasigna? I think my mother is

relapsing too, she had been pcru for 6 years on gleevec and

> > now she is pcr 0.216

> > I´m really worried,

> > she was taking nexium to protect her stomach, and maybe that makes gleevec

levels lower?

> > as I said, I´m really worried

> __________________________________________________

>

> Hi Ana,

> Your mother needs to get off the Nexium....it is a proton pump inhibitor and

it is interferring with her cml drug. This has been determined now.

>

> You need to see what happens over the course of a few pcr tests, they could be

done sooner, even once a month.....to determine if she is really relapsing on

this drug. And then, or even now, she should have a mutation test done to see if

she has developed a mutation that is making the drug not work.

>

> Acid in the stomach is normal, you need it for digestion and also the cml

drugs need acid for absorption. If she has acid reflux, look at changing diet

and avoiding some really acid foods (esp. soda and sugar. Even diet soda, it is

the carbonation).

>

> C.

>

>