Guest guest Posted January 31, 2011 Report Share Posted January 31, 2011 Shelagh was at a conference in the UK and has been trying to post the messages, but unable to do so, so I am going to try and see if I have any success. I told her we were all like hounds yelping to be fed - information that is. We have varocious appetites for all articles that have the CML acronynm in bold letters. Published: 24/01/2011 12:27:29 Scientists at the University of East Anglia have discovered a rogue gene which – if blocked by the right drugs – could stop cancer in its tracks.Published today by the journal Oncogene, the discovery is a breakthrough in our understanding of how cancer spreads. It is hoped the research will lead to new drugs that halt the critical late stage of the disease when cancer cells spread to other parts of the body. " The culprit gene – known as WWP2 - is an enzymic bonding agent found inside cancer cells. It attacks and breaks down a natural inhibitor in the body which normally prevents cancer cells spreading. The UEA team found that by blocking WWP2, levels of the natural inhibitor are boosted and the cancer cells remain dormant. If a drug was developed that deactivated WWP2, conventional therapies and surgery could be used on primary tumours, with no risk of the disease taking hold eleswhere " . ...read more ********************** Seeking the causes and solutions to imatinib-resistance in chronic myeloid leukemia D. Bixby and M. Talpaz Division of Hematology and Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, US Is this a description of your history????? " .....one-third of patients will still have an inferior response to imatinib, either failing to respond to primary therapy or demonstrating progression after an initial response. read PDF here: http://www.nature.com/leu/journal/v25/n1/pdf/leu2010238a.pdf www.cmlsupport.org.uk Thanks, Shelagh Lottie Duthu Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 31, 2011 Report Share Posted January 31, 2011 WOW That's very interesting...Gay On Jan 30, 2011, at 9:05 PM, Lottie Duthu wrote: > Shelagh was at a conference in the UK and has been trying to post > the messages, but unable to do so, so I am going to try and see if I > have any success. > I told her we were all like hounds yelping to be fed - information > that is. We have varocious appetites for all articles that have the > CML acronynm in bold letters. > > Published: 24/01/2011 12:27:29 > > Scientists at the University of East Anglia have discovered a rogue > gene which – if blocked by the right drugs – could stop cancer in > its tracks.Published today by the journal Oncogene, the discovery is > a breakthrough in our understanding of how cancer spreads. It is > hoped the research will lead to new drugs that halt the critical > late stage of the disease when cancer cells spread to other parts of > the body. > > " The culprit gene – known as WWP2 - is an enzymic bonding agent > found inside cancer cells. It attacks and breaks down a natural > inhibitor in the body which normally prevents cancer cells > spreading. The UEA team found that by blocking WWP2, levels of the > natural inhibitor are boosted and the cancer cells remain dormant. > If a drug was developed that deactivated WWP2, conventional > therapies and surgery could be used on primary tumours, with no risk > of the disease taking hold eleswhere " . ...read more > > ********************** > > Seeking the causes and solutions to imatinib-resistance in chronic > myeloid leukemia > > D. Bixby and M. Talpaz > > Division of Hematology and Oncology, Department of Internal > Medicine, University of Michigan, Ann Arbor, MI, US > > Is this a description of your history????? > > " .....one-third of patients will still have an inferior response to > imatinib, either failing to respond to > > primary therapy or demonstrating progression after an initial > response. > > read PDF here: > > http://www.nature.com/leu/journal/v25/n1/pdf/leu2010238a.pdf > > > www.cmlsupport.org.uk > > Thanks, Shelagh > > Lottie Duthu > > > > > > Quote Link to comment Share on other sites More sharing options...
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