Guest guest Posted February 18, 2011 Report Share Posted February 18, 2011 I am posting an article about lupus, because I always test positive for it, even though the doctor believes it is a false positive. It occurred to me that others in the group may have been diagnosed with Lupus, so I am passing it on. Dana Farber at Harvard is doing research on this subject. Failed autoimmune suppression mechanism new clue to lupus Date: February 2, 2011 Bar Harbor, Maine — Researchers at Dana-Farber Cancer Institute in Cambridge, Mass., in collaboration with Laboratory scientists, have identified a regulatory defect that drives lupus. Correcting the defect “may represent an effective therapeutic approach to systemic lupus erythematosus-like autoimmune disease,” the researchers state in their research paper, published in the Proceedings of the National Academy of Sciences. The research team was led by Harvey Cantor, M.D., chair of the department of cancer immunology and AIDS at Dana-Farber, in collaboration with the laboratory of Professor Derry Roopenian, Ph.D. Autoimmune diseases develop when the immune system, which is supposed to identify and vanquish potentially dangerous infectious agents, instead attacks the individual's own body. Most autoimmune diseases strike specific organs, such as the pancreas in type 1 diabetes. Lupus, however, is a systemic disease in which abnormal antibodies are produced throughout the body, inflaming a variety of tissues and organs, including the skin, heart, lungs, kidneys and brain. Follicular T helper (TFH) cells fuel B cells to produce antibodies, which can be useful in fighting infections. But in lupus, TFH fuel B cells that produce dangerous antibodies that attack normal tissues (autoantibodies). CD8+ T cells (“killer T cells”), on the other hand, normally attack and destroy only infected cells. Cantor and colleagues discovered that a small, but critically important, population of CD8+ T cells (less than 5 percent), plays a specialized role in protecting from lupus. These so-called CD8+ T regulatory, or Treg, cells are specially equipped to destroy TFH cells, and by doing so, prevent lupus from developing. http://www.jax.org/news/archives/2011/lupus.html?readmor **************************** Medical Author: B. Driver, MD What is osteopenia? Should I be worried???? Osteopenia is a bone condition characterized by a decreased density of bone, which leads to bone weakening and an increased risk of breaking a bone (fracture). Osteopenia and osteoporosis are related conditions. In osteopenia, however, the bone loss is not as severe as in osteoporosis. That means someone with osteopenia is more likely to fracture a bone than someone with a normal bone density but is less likely to fracture a bone than someone with osteoporosis. Osteomalacia, osteomyelitis, and osteoarthritis are different conditions that are frequently confused with osteopenia because they sound similar. Osteomalacia is a disorder of the mineralization of newly formed bone, which causes the bone to be weak and more prone to fracture. http://www.medicinenet.com/osteopenia/article.htm ***************************** Posted by Nova Simpson, Pharm.D. Studies have shown that if a person that is having a heart attack chews a tablet of aspirin 325mg (or 4 tablets of aspirin 81mg), it can limit damage that happens during a heart attack (of course, you still call 9-1-1!). Now there is a new rumor out there on the world wide web about taking Bayer Crystals instead of aspirin for the prevention of heart attacks. I am sure you are now holding your breath to see if the rumor is true or false…..it is….FALSE! The Bayer Crystals do not work better to prevent heart attacks. In addition, the Bayer Crystals could be harmful in a person having a heart attack for a couple of reasons: 1. The Crystals contain 65mg of caffeine and 2. The Crystals contain 850mg of aspirin – much more than the recommended 325mg! (no, more is not better) ***Take care- most aspirin powders (like Goodys and BC) also have high levels of aspirin and caffeine*** http://tinyurl.com/4d4j6rf ************************ Enteric coated or buffered means that there is a special coating on the aspirin tablet that will delay the release of the medicine until it reaches the small intestine. Aspirin can bother the belly –so the coating can help lessen the irritation. However, because it delays the release of aspirin –it is much, much, much better to chew a non-buffered aspirin during a heart attack. http://tinyurl.com/48f5vvq ***************************** FYI, Lottie Duthu Monday was the day sacred to the moon, when that planet was worshipped with great reverence by the ancient Saxons. It was first named " Moon Day " and later changed to the current spelling of Monday. (Also called Lunar day). Quote Link to comment Share on other sites More sharing options...
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