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Good, I thought somebody would find it useful.

Pat, I sent you a longish message last night privately, I was wondering why you had not responded when you are oboviously busy on the forum, so went to check in my 'Sent' box that it had actually gone. I cannot find that I have sent it to you - did you receive anything from me. This is a real mystery. Seems I will have to write it all out again. Drat - these things just shouldn't happen, especially when I feel shattered at the moment.

Let me know privately if you received anything from me to sheilaturner@...

Luv - Sheila

It isn't Dawn here, but thanks for posting this website address Sheila. Very useful! I've placed it in my 'favourites'PNo virus found in this incoming message.

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Just seems that diazepam has a problem with grapefruit and alcohol,

nothing else comes up, nothing on their for my water pills though. So

seems I should be ok with the mix according to that :)

cheers hon

lotsa luv

Dawnx

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You know Dawn - I have had that information tucked away in my own files for an absolute age, and had completely forgotten about it. I was cleaning up yesterday and came across it. Have you been able to use it and has it helped you in deciding whether or not your list of medications were causing interactions with each other?

Luv - Sheila

Woop:)Thanks Shiela hon, yes, very useful.Perhaps the head of my PCT should have used one of these when I wroteto him lol.lotsa luvDawnxNo virus found in this incoming message.

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Hi Bob

Yes, Dawn did get an idiotic, irresponsible, couldn't care less response from that particular pharmacist.

I had promised Dawn I would help with a suitable response, and I am so sorry Dawn that I never got around to doing this. Part of the excuse for delaying this was that the pharmacist from the PCT was about to go away on holiday (I think this could have been the reason why he didn't bother going into this matter deep enough). However, it is never too late to respond, but i will have to dig around to find it in my correspondence. Apologies for this delay Dawn, but sometimes, I don't know whether I, on my head or my feet these days, life just seems to be betting busier and there is more and more that needs doing.

Luv - Sheila

Hi Dawn Did you get a useful response from the PCT?Bob> Woop:)> Thanks Shiela hon, yes, very useful.No virus found in this incoming message.

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Hiya

Well Shiela, I don't really think I have so much of an interraction as

a problem with the drugs themselves, insomuch as they are very bad for

me. No interractions can be found from my own perspective but a lot of

my symptoms do come up as withdrawal and side effects of the 2 prime

drugs Seroxat and epam. I have run out of Olmatec and not had any

for nearly a week, waiting to see if I have a rebound bp rise, if not,

I will stay off it. Bob, as Shiela says, I was just told that he did

not endorse my Armour and he made a great point of that because

apparently thyroxine is a safe and effective treatment despite the

fact I was having horrendous hypo symptoms and things running down on

it, for a treatment that is safe and effective it just wasn't doing

the job, but you know this Bob, and all the guy went on about was my

supplements and the dangers of poly pharmacy. I haven't had chance or

health to write back to them yet sadly. I am trying so hard to tackle

the disease haven't time for much else with the state I am in. Thanks

for asking Bob :) and Shiela, I know you are so very very busy, and

doing so well too, all I have heard has been positive whilst I have

read the posts when I have been able to come online :).

Not been to sleep yet again, ah well, morning morning to all, and hugs

all round to my friends

lotsa luv

Dawnx

>

> You know Dawn - I have had that information tucked away in my own

files for an absolute age, and had completely forgotten about it. I

was cleaning up yesterday and came across it. Have you been able to

use it and has it helped you in deciding whether or not your list of

medications were causing interactions with each other?

>

> Luv - Sheila

>

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Hi Dawn

I hope you get your lap-top back soon, we do miss you being around - it's just not the same place. I was looking for the letter from the pharmacist at the PCT talking about poly pharmacy - but can't find it anywhere. Will you send it to me again when you get your computer back and I will try to make some time to respond and send it back to you. It would be so good if these people actually studied the facts and not just copied the statements about Armour from the BTA website. It just staggers me that NHS doctors are giving out both misleading and incorrect information .

luv - Sheila

Bob, as Shiela says, I was just told that he didnot endorse my Armour and he made a great point of that becauseapparently thyroxine is a safe and effective treatment despite thefact I was having horrendous hypo symptoms and things running down onit, for a treatment that is safe and effective it just wasn't doingthe job, but you know this Bob, and all the guy went on about was mysupplements and the dangers of poly pharmacy. I haven't had chance orhealth to write back to them yet sadly. I am trying so hard to tacklethe disease haven't time for much else with the state I am in. Thanksfor asking Bob :) and Shiela, I know you are so very very busy, anddoing so well too, all I have heard has been positive whilst I haveread the posts when I have been able to come online :).

..

No virus found in this incoming message.Checked by AVG - http://www.avg.com Version: 8.0.169 / Virus Database: 270.6.13/1642 - Release Date: 29/08/2008 18:12

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Thankyou Shiela

I miss being active here too, its hard with this as it keeps locking

up. Not heard what is happening with my lappy, no doubt everything is

going at a British workmens pace hehe, cuppa tea anyone?

I will indeed send the letter to you when I get it back, I feel

humbled by the amount of work you are doing and also thankyou.

take care

God bless

Dawnx

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  • 4 months later...

Lorazepam is ok to take with LDN. Before I started LDN in 2005 I was on Vicodin for 8 months and I was told by Skip's Pharmacy I had to be off it for a month before I could start my LDN but I think I only waited 2 weeks then started LDN and I was ok. I felt some of the benefits the first night I took LDN. Unless its changed thats what I was told back in 2005. You may want to call Skip's to make sure how long you have to be off the kadian (morphine drug) before you start LDN. Here is their contact info -

http://www.skipspharmacy.com/?pgname=contact

Also here is a list of "What NOT to take with LDN!!

Do not take LDN (Naltrexone) with any of the following:

• disulfiram (Antabuse);• thioridazine (Mellaril);• buprenorphine (Buprenex, Subutrex);• codeine (Tylenol with Codeine, and other brand names);• hydrocodone (Lorcet, Lortab, Vicodin, Vicoprofen, and other brand names);• hydromorphone (Dilaudid);• levorphanol (Levo-Dromoran);• meperidine (Demerol);• methadone (Dolophine, Methadose);• morphine (Kadian, MS Contin, MSIR, OMS, Roxanol, Oramorph SR, and other brand names);• oxycodone (M-Oxy, OxyContin, OxyIR, Roxicodone, Percocet, Percodan, and other brand names);• oxymorphone (Numorphan); or• propoxyphene (Darvon, and other brand names).

· Ultram (tramadol)

· Novantrone

· Rebif

· Avonex

· Betaseron

· Tysabri

· Chemo's

· Cellcept is a chemotherapy

· methotrexate

· Remicade - Called Skip's Pharmacy at the suggestion of people in this group, and the pharmacist there told me you have to be off Remicade for 50 days before starting LDN. Since the two meds have opposing effects on the immune system, LDN won't work while on Remicade. http://www.skipspha rmacy.com/

· 6MP - called Skip's about 6MP they said you should be off it for about a week before starting LDN.It sounded like you wouldn't want to take 6MP concurrent with LDN, since 6MP is an immunosuppressant and would have opposing effect on immune system as LDN.

· Humira

Dr. Jill said to stop Humira for 2 weeks before starting on LDN.

And this was the reply I got when I asked the question if we had to stop Humira before starting LDN on the LDN website:

A person with Crohn's who receives Humira can begin LDN immediately (because H. is not a narcotic and thus is not contraindicated) -- however, Humira's effects in suppressing the immune system can seriously blunt the potential benefits from LDN (which should strengthen the immune system). The sooner off Humira, which is dangerous, the better.

Ø Cautionary warnings:

Because LDN blocks opioid receptors throughout the body for three or four hours, people using medicine that is an opioid agonist, i.e. narcotic medication — such as Ultram (tramadol), morphine, Percocet, Duragesic patch or codeine-containing medication — should not take LDN until such medicine is completely out of one's system. Patients who have become dependant on daily use of narcotic-containing pain medication may require 10 days to 2 weeks of slowly weaning off of such drugs entirely (while first substituting full doses of non-narcotic pain medications) before being able to begin LDN safely.

I believe that steroids, short term, are ok with LDN.

Dr. Skip

Drugs that may interact with Low Dose Naltrexone

Generic Name

Brand Name*

Mixed Opiate Agonists/Antagonists

Buprenorphine

Buprenex®, Suboxone®, Subutex®

Butorphanol

Dorolex®, Stadol®

Nalbuphine

Nubain®

Pentazocine

Naloxone®, Talwin®

Opiate Agonists

Alfentinil

Alfenta®

Clonidine

Catapres®

Codeine

N/A

Dronabinol, THC

Marinol®

Fentanyl

Duragesic®, Aqtic®, Sublimaze®, Fentora®

Hydrocodone

Lorcet®, Lortab®, Vicodin®

Hydromorphone

Dilaudid®

Levorphanol

Levo-Dromoran®

Meperidine

Demerol®, Meperitab®

Methadone

Dolophine®, Methodose®

Morphine

Kadian®, MSContin®

Oxycodone

Percocet®, Endocet®, Roxicodone®, Endocodone®

Oxymorphone

Opana®, Numorphone®

Propoxyphene

Darvocet®, Darvon®

Remifentinil

Ultiva®

Sufentinil

Sufenta®

Other Medications

Disulfuram

Antabuse®

Dronabinol, THC

Marinol®

Nabilone

Cesamet®

Thioridazine

Mellaril®

Clonidine

Catapres®

* May not include each brand name available on the market in the United States

References:

Clinical Pharmacology Online @ www.clinicalpharmacology.com (accessed 06/14/07)

In addition, because LDN stimulates the immune system and many of the drugs routinely used by the NHS in the treatment of MS further suppress the immune system, LDN cannot be used in company with steroids, beta interferon, methotrexate, azathioprine or mitozantrone or any other immune suppressant drug. If there is any doubt, please submit a full list of the drugs you are presently taking so that their compatibility may be assessed. In addition, because LDN will also block the analgesic effects of any opiate drugs (includes codeine, dihydrocodeine, morphine, pethidine or diamorphine) presently being taken, the use of LDN will initially greatly increase the level of pain experienced. It is therefore advisable that any opiate-like drugs be discontinued at least two weeks before this treatment is

initiated."

May there be a miracle in YOUR life today and may you have the EYES to see it.From My Heart to Yours Love, Hugs & Blessings, CrystalLDN_Users Group OwnerDiagnosed November 2004 with Secondary Progressive MS, Transverse Myelitis and an Advocate for LDN!! 3 years on LDN with Skip's Pharmacy.....No Relapses.....Crystal's MS,TM & LDN Websitehttp://www.freewebs.com/crystalangel6267/index.htm LDN Website http://ww.ldninfo.org/Crystal's LDN Support GroupLDN_Users/

LDN MySpace

http://www.myspace.com/low dose naltrexone

Cris - Case Health - Health Success Storieshttp://casehealth.com/case/about.html

Crystal's LDN Gift Shophttp://www.cafepress.com/crystalldngifts Skip's Compounding Pharmacyhttp://www.skipspharmacy.com/

From: cpillow53 <cpillow53@...>low dose naltrexone Sent: Wednesday, January 28, 2009 4:45:06 PMSubject: [low dose naltrexone] drug interactions

Are there any known interactions with Lorazepam. This is a non-narctotic sleep aid. Also how long do you need to be off kadian (morphine drug) before starting the ldn?

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  • 4 months later...
Guest guest

Drugs not to take with LDN

LDN will block the analgesic effects of any opiate drug. This is a list of

drugs, over the counter meds and some street drugs that shouldn't be taken with

LDN. They include but are not limited to:

6MP – Need to be off 1 week

Acetyldihydrocodone

Actifed with Codeine Cough Syrup ®

Actiq ®

Alfenta ®

Alfentinil

Ambenyl

Amogel PG ®

Antibuse ®

Aspirin with Codeine

Astramorph PF ®

Avonex

Betaseron

Broncholate CS

Buprenex ®

Buprenorphine

Butorphanol

Capital and Codeine Oral Solution

Catapres ®

Cellcept

Cesamet ®

Cheracol

Clonidine

Codeine

Codinal PH ®

Darvocet ®

Deconsal

Demerol ®

Diabismul ®

Diamorphine

Dihydrocodeine

Dilaudid ®

Dimetane-DC Cough Syrup ®

Diphenoxylate

Disulfiram

Doda

Dolophine ®

Donnagel-PG ®

Dovolex ®

Dronabinol, THC

Duragesic ®

Duramorph ®

Emprin with Codeine ®

Endocet ®

Endocodone ®

Fentanyl

Fentora ®

Fioricet with Codeine ®

Fiorinal with Codeine ®

Heroin

Humira – Need to stop 2 weeks before

Hycodan ®

Hydrocodone

Hydromorphone

Hyrocane

Imidium AD ®

Infantol Pink ®

Infumorph

Isoclor Expectorant

Kadian ®

Kaodene with Codeine®

Kaodene with Paregoric ®

LAAM

Laudanum

Levorphanol

Levo-Dromoran ®

Lomotil

Lorcet ®

Lortab ®

Marinol ®

Mellaril ®

Meperidine

Meperitab ®

Methadone

Methadose ®

Methotrexate

Morphine

M-Oxy

MSIR ®

Nabilone ®

Nalbuphine

Naloxone ®

Norco

Novahistine DH ®

Novahistine Expectorant

Novantrone

Nubain ®

Nucofed Expectorant

Numorpan ®

Numorphone ®

OMS

Opana ®

Opium

Oramorph

Oxycodone

Oxycontin

OxyIR

Oxymorphone

Paracodine ®

Paregoric

Par-Glycerol-C (CV)

Pentazocine

Percocet ®

Percodan ®

Pethidine

Pediacof ®

Phenaphen with Codeine ®

Phenergan with Codeine ®

Phenergan VC ®

Poly-Histine

Promethazine VC with Codeine

Propoxyphene

Rebif

Remicade – Must be off 50 days

Remifentinil

Rescudose

Robitussin A-C ®

Robitussin DAC ®

Roxanol

Roxicodone ®

Soma with Codeine

Stadol ®

Sublimaze ®

Suboxone

Subutrex ®

Sufenta ®

Sufentinil

Talwin ®

Thioridazine

Tramadol

Triaminic Expectorant with Codeine ®

Tussionex

Tussi-Organiden

Tylenol with Codeine ®

Tylenol with Codeine (#1, 2, 3, or 4)

Tylox

Tysabri

Tussar-2 ®

Tussar SF ®

Ultiva ®

Ultram

Vicodin ®

Vicoprofen

Xodol

Zydone

It is necessary to discontinue any opiate-like drug for 10 days to two weeks

prior to starting LDN. If you should take an opiate type drug while taking LDN

their effects will cancel each other out. If you will be needing surgery, you

should not take LDN for 24 to 48 hours previously. You may then resume the LDN

24 to 48 hours after the last dose of an opiate containing drug.

Note: The list is only a representative sample of the prescription and

non-prescription medications that contain codeine or morphine.

There are also a few other drugs that are immune suppressants that it is advised

that should not be combined with LDN. These include but are not limited to:

Azathioprine

Beta Interferon

Methotrexate

Mitozantrone

Steroids (may be used in doses of 5-10 mg if needed)

It is important to submit to your doctor a full list of the drugs you are

presently taking so that their compatibility may be assessed.

>

> I take Lamictal for a mild seizure disorder (well controlled), but I cannot

stop taking it or I will have a seizure.

>

> Does anyone know about drug interactions with Lamictal (and/or LDN and

seizures)?

>

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Guest guest

Seizure meds are okay to take with LDN.

==========

>

> I take Lamictal for a mild seizure disorder (well controlled), but I cannot

stop taking it or I will have a seizure.

>

> Does anyone know about drug interactions with Lamictal (and/or LDN and

seizures)?

>

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  • 1 year later...

Thanks Leah, I had never visited that website, but the information is

invaluable.

I do take a few of the drugs on the list for B/P.

Diltiazem is listed as a drug that increases plasma concentrations and also that

plazma

concentrations may be affected. Not sure I understand the two explanations,

they sound alike.

There are some OTC drugs that also affect the concentrations in the blood, as

well as some fruits, so we need to be aware of them. Some innocuous things like

tea and so called natural drugs could also be dangerous. Now Pom is featured in

the produce

department. I bought some, but then read somewhere that is could be harmful.

Thanks to some of the ladies in the group who raved about juicing, I now do my

own juicing and use whatever I like and is also good for me. The last time I

added an extra lemon and found it a bit too tart. The lesson here is to proceed

with caution and check everything out before ingesting it. I read the labels

like never before. Thanks for the tip, it was well worth reading and I printed

a copy for my files. Now know where I can find someone to help me with my

filing? LOL

Carpe Diem,

Lottie Duthu

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Hi Lottie,

I am not sure what " plasma concentrations " actually are, but I would assume that

" affected " can mean they can either go up or down...

Another point that it is important to make re drug interactions is that, like

side effects, they are very individual. A person who is very drug sensitive

(like me ;-) may be more likely to notice the effects of food and drug

interactions.

I have read of a number of people on the chats who regularly drink green tea.

This is on the list as " may cause increase or decrease " of effective dose. I had

green tea for 3-4 days in a row (just a single mug) and broke out in major

hives, as if I had increased my Sprycel dose back up to 100 mg. Same for

pomegranate - I forgot and had ONE DRINK that included Pomegranate juice and

felt pretty ill within 4 hours, and it lasted for a whole day.

So, as you point out, we need to be aware of the potential problems. Pre CML I

was very much into herbs and it is quite frustrating to basically have banned

them from my treatment arsenal. I am so afraid of interactions (being as

sensitive as I am - the list of drugs I am allergic too seems to grow every time

I take one!) I usually just tough out any minor illnesses (lots of fluids and

time in bed) rather than risk taking a drug (prescription or OTC).

Fortunately, other than CML, I am healthy and don't need to take anything else

regularly.

best,

Leah

>

> Thanks Leah, I had never visited that website, but the information is

invaluable.

> I do take a few of the drugs on the list for B/P.

>

> Diltiazem is listed as a drug that increases plasma concentrations and also

that plazma

> concentrations may be affected. Not sure I understand the two explanations,

they sound alike.

>

> There are some OTC drugs that also affect the concentrations in the blood, as

well as some fruits, so we need to be aware of them. Some innocuous things like

tea and so called natural drugs could also be dangerous. Now Pom is featured in

the produce

> department. I bought some, but then read somewhere that is could be harmful.

Thanks to some of the ladies in the group who raved about juicing, I now do my

own juicing and use whatever I like and is also good for me. The last time I

added an extra lemon and found it a bit too tart. The lesson here is to proceed

with caution and check everything out before ingesting it. I read the labels

like never before. Thanks for the tip, it was well worth reading and I printed

a copy for my files. Now know where I can find someone to help me with my

filing? LOL

>

> Carpe Diem,

> Lottie Duthu

>

>

>

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