Guest guest Posted December 8, 2008 Report Share Posted December 8, 2008 This is a repost since I hadn't heard from anyone in response to my first, titled, " Math- and logic-check me, will ya? " I've also inserted a paragraph to help you follow what I'm doing with these calculations. Very long time no show..... But tonight I've been going through the RIFM's Position Statement on Methyl Eugenol…, trying to put the puzzle together. It's been several hours now. Gettin' closer. And I need help. Working with the " Calculation table for dermal exposure " on the last page of that document, I've come up with the following. Someone please check it over and let me know what I'm not seeing. ..3 gram of perfume applied (per day per 60-kg person)... that's from the PERFUME EXTRACTS row 20% of that is " fragrance " (column 6) So, .3g * .20 = .06 gram of fragrance applied per day That's .06 g * 1000 mg/g = 60 mgs fragrance applied per day 60 mgs * 1000 MICROgrams = 60,000 MICROgrams total fragrance per day 60,000 MICROgrams/60 kgs of bodyweight = 1000 MICROgrams of fragrance per kg of bodyweight per day (that's the figure in the last column of their chart) I think this data above is suggesting that RIFM is supposing that the average person will apply .3 gram of perfume per day and that the perfume will be of 20% concentration... So, that's the base for determining how much of a restricted material (like methyleugenol) can be used. My attempts to follow their calculations and logic (as well as insert my own??) are continued below. Now, if I understand correctly, RIFM is proposing that a (lower end) max of 150 MICROgrams (of the fragrance) be of methyleugenol. So I'll divide 150 micrograms by 1000 micrograms and get that 15% of the total fragrance can be from methyleugenol. So, .15 * .20 = .03 That's 3%. 3% of the 20%. 3% ME of the 20% fragrance or .03 * .2 = .6% ME of the perfume Now I'll go to a fragrance containing the restricted component methyleugenol. Rose oil. I'll assume 3.5% ME in the rose oil. So, .006/.035 = .1714 So 17.14% rose oil (containing 3.5% ME) in the perfume would give a ..6% ME concentration in the perfume. But still…where'd they get .02% max concentration of ME???? (Page 1 of the document isn't helping me; I can't understand where they got 2,547 mg/kg body weight/day.) If the .02% is accurate, that'd allow only .57% of the same rose oil. Giant difference: .57% vs. 17.14%. Help me, help me, Jen Quote Link to comment Share on other sites More sharing options...
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