Anyone KNow What MCI means regarding Fusarium statement?

[Guest guest]

Does anyone know what this MCI means in this context:

" Susceptibility

Fusarium is one of the most drug-resistant fungi. Among the Fusarium

spp., Fusarium solani in general tends to be most resistant of all.

Fusarium strains yield quite high MICs for flucytosine, ketoconazole,

miconazole, fluconazole, itraconazole, and posaconazole [118, 1438,

1861, 1906, 2290, 2291]. The novel triazole, Syn-2869, has no activity

against Fusarium [1132]. Fusarium spp. are intrinsically resistant to

the novel glucan synthesis inhibitors, caspofungin, anidulafungin, and

micafungin [119, 557, 682, 1786, 2234]. Despite the lack of its

activity alone, the combination of caspofungin with amphotericin B

appears synergistic against some Fusarium isolates [120]. "

I hoping it isn't referring to mycotoxins.

[Guest guest]

MIC means ”Minimum inhibitory concentration”. It is a test that is used to

determine the minimum amount of an antibiotic required to kill an organism.

_____

From: [mailto: ] On

Behalf Of barb1283

Sent: 31 October 2006 07:23

Subject: [] Anyone KNow What MCI means regarding Fusarium

statement?

Does anyone know what this MCI means in this context:

" Susceptibility

Fusarium is one of the most drug-resistant fungi. Among the Fusarium

spp., Fusarium solani in general tends to be most resistant of all.

Fusarium strains yield quite high MICs for flucytosine, ketoconazole,

miconazole, fluconazole, itraconazole, and posaconazole [118, 1438,

1861, 1906, 2290, 2291]. The novel triazole, Syn-2869, has no activity

against Fusarium [1132]. Fusarium spp. are intrinsically resistant to

the novel glucan synthesis inhibitors, caspofungin, anidulafungin, and

micafungin [119, 557, 682, 1786, 2234]. Despite the lack of its

activity alone, the combination of caspofungin with amphotericin B

appears synergistic against some Fusarium isolates [120]. "

I hoping it isn't referring to mycotoxins.

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