the bigger the body the greater the disk dz!

[Guest guest]

From the "Duh" file! Seitz, DC Tuality Physicians 730-D SE Oak St Hillsboro, OR 97123 (503)640-3724The association of lumbar intervertebral disc

degeneration on magnetic resonance imaging with body mass index in overweight

and obese adults: A population-based study

Dino Samartzis1,*, Jaro Karppinen2, Danny

Chan1, D. K. Luk1, M. C. Cheung1,‡,*

Article first published online: 26 APR 2012 DOI: 10.1002/art.33462

Arthritis & Rheumatism

Volume 64, Issue 5, pages

1488–1496, May 2012

Abstract

Objective

To investigate the association of being overweight or obese

with the presence, extent, and severity of lumbar disc degeneration on magnetic

resonance imaging (MRI) in adults.

Methods

A population-based cross-sectional study of 2,599 southern

Chinese volunteers was conducted. Subjects underwent radiographic and clinical

assessment, and weight and height were measured. Sagittal T2-weighted MRIs of

the lumbar spine were obtained. The presence, extent, and severity of disc

degeneration and additional radiographic and clinical parameters were assessed.

Asian-modified body mass index (BMI) (kg/m2) categories were used.

Odds ratios (ORs) and 95% confidence intervals (95% CIs) were calculated.

Results

The study included 1,040 men and 1,559 women (mean age 41.9

years). Disc degeneration was noted in 1,890 subjects (72.7%). BMI was

significantly higher in subjects with disc degeneration (mean 23.3 kg/m2)

than in subjects without degeneration (mean 21.7 kg/m2) (P <

0.001). A significant increase in the number of degenerated levels (P <

0.001), global severity of disc degeneration (P < 0.001), and

end-stage disc degeneration with disc space narrowing (P <

0.001) was noted with elevated BMI, in particular in overweight and obese

subjects. In the adjusted multivariate logistic regression model, there was a

positive linear trend (r2 = 0.99) between BMI and the overall

presence of disc degeneration in overweight (OR 1.30 [95% CI 1.03–1.62]) and

obese (OR 1.79 [95% CI 1.17–2.74]) subjects. End-stage disc degeneration with

disc space narrowing was significantly more pronounced in obese subjects

(adjusted OR 1.72 [95% CI 1.23–2.41] [reference normal weight]).

Conclusion

Our findings, in one of the largest studies to

systematically assess lumbar disc degeneration on MRI, indicated a significant

association between the presence, extent, and global severity of disc

degeneration with weight in overweight and obese adults.

[Guest guest]

and research money was spent on this. Some of what the allopaths do just makes me shake my head! slkSunny Kierstyn, RN DC Fibromyalgia Care Center of Oregon 2677 Willakenzie Road, 7CEugene, Oregon, 97401541- 654-0850; Fx; 541- 654-0834www.drsunnykierstyn.com To: oregondcs From: dcdocbrian@...Date: Tue, 29 May 2012 09:39:21 -0700Subject: the bigger the body the greater the disk dz!

From the "Duh" file! Seitz, DC Tuality Physicians 730-D SE Oak St Hillsboro, OR 97123 (503)640-3724The association of lumbar intervertebral disc

degeneration on magnetic resonance imaging with body mass index in overweight

and obese adults: A population-based study

Dino Samartzis1,*, Jaro Karppinen2, Danny

Chan1, D. K. Luk1, M. C. Cheung1,‡,*

Article first published online: 26 APR 2012 DOI: 10.1002/art.33462

Arthritis & Rheumatism

Volume 64, Issue 5, pages

1488–1496, May 2012

Abstract

Objective

To investigate the association of being overweight or obese

with the presence, extent, and severity of lumbar disc degeneration on magnetic

resonance imaging (MRI) in adults.

Methods

A population-based cross-sectional study of 2,599 southern

Chinese volunteers was conducted. Subjects underwent radiographic and clinical

assessment, and weight and height were measured. Sagittal T2-weighted MRIs of

the lumbar spine were obtained. The presence, extent, and severity of disc

degeneration and additional radiographic and clinical parameters were assessed.

Asian-modified body mass index (BMI) (kg/m2) categories were used.

Odds ratios (ORs) and 95% confidence intervals (95% CIs) were calculated.

Results

The study included 1,040 men and 1,559 women (mean age 41.9

years). Disc degeneration was noted in 1,890 subjects (72.7%). BMI was

significantly higher in subjects with disc degeneration (mean 23.3 kg/m2)

than in subjects without degeneration (mean 21.7 kg/m2) (P <

0.001). A significant increase in the number of degenerated levels (P <

0.001), global severity of disc degeneration (P < 0.001), and

end-stage disc degeneration with disc space narrowing (P <

0.001) was noted with elevated BMI, in particular in overweight and obese

subjects. In the adjusted multivariate logistic regression model, there was a

positive linear trend (r2 = 0.99) between BMI and the overall

presence of disc degeneration in overweight (OR 1.30 [95% CI 1.03–1.62]) and

obese (OR 1.79 [95% CI 1.17–2.74]) subjects. End-stage disc degeneration with

disc space narrowing was significantly more pronounced in obese subjects

(adjusted OR 1.72 [95% CI 1.23–2.41] [reference normal weight]).

Conclusion

Our findings, in one of the largest studies to

systematically assess lumbar disc degeneration on MRI, indicated a significant

association between the presence, extent, and global severity of disc

degeneration with weight in overweight and obese adults.