Re: High levels of B12 and Folate in blood

[Guest guest]

NHS labs look at the shape of the blood cell to check B12 sufficiency

automatically for every test because it is so straightforward. If they

have not flagged one then they have not seen anything wrong with the B12

status.

Sally

JULIE GRIFFITHS wrote:

>

> ,

>

> With all the gut problems typically demonstrated in autism, I cannot

> uinderstand how a high B12 would come about....low, yes...but high???

>

> Blood levels are NOT a strong indicator of B12. You have to look at the

> type of red blood cells the bone marrow is throwing out. From memory,

> the best indicator is maturity and number of RBCs This is recorded in

> the CBC (Complete Blood Count......MCV etc)......Have a look into

> this........This may be why there is a discrepancy betwen th OATS and

> the NHS.

>

>

>

> Scorer schrieb:

> >

> >

> >

> > We have had some blood tests done on NHS to further investigate the

> > cause of ds's epilepsy. The findings so far indicate high levels of B12

> > and Folate.

> >

> > I'm not sure but thought I'd heard/read somewhere that the levels of B12

> > in the blood are not indicative of the levels of B12 in the

> > brain/nervous system (?) and that therefore if there is high levels in

> > the blood this is not a good indicator of the B12 status as such. I'm

> > sorry I don't know how to explain this but hope someone understands this

> > to explain it better. And what about Folate? Would it be the same?

> >

> > I've been giving Folinic with B12 from Kirkman, so now wondering whether

> > to discontinue/reduce.

> >

> > Any knowledge on this would be gratefully received.

> >

> > emily

> >

> >

> > ----------------------------------------------------------

> >

> > No virus found in this incoming message.

> > Checked by AVG.

> > Version: 7.5.518 / Virus Database: 269.21.7/1322 - Release Date:

> 09/03/2008 12:17

> >

>

>

> ------------------------------------------------------------------------

>

> No virus found in this incoming message.

> Checked by AVG Free Edition.

> Version: 7.5.516 / Virus Database: 269.21.7/1322 - Release Date: 09/03/2008

12:17

>

[Guest guest]

High levels, YES! that does not mean person is utilising it - converting

to the form that is needed by the body.

usually the kids with the highest levels of b12 are the ones who need

methylcobalamin the most! if he is a responder do not stop shots/spray

just because blood levels are high.

that is apparently the case in many other disorders, not autism.

not sure about high folate though...

natasa

>

> ,

>

> With all the gut problems typically demonstrated in autism, I cannot

> uinderstand how a high B12 would come about....low, yes...but high???

>

> Blood levels are NOT a strong indicator of B12. You have to look at

the

> type of red blood cells the bone marrow is throwing out. From memory,

> the best indicator is maturity and number of RBCs This is recorded in

> the CBC (Complete Blood Count......MCV etc)......Have a look into

> this........This may be why there is a discrepancy betwen th OATS and

> the NHS.

>

>

>

> Scorer schrieb:

> >

> >

> >

> > We have had some blood tests done on NHS to further investigate the

> > cause of ds's epilepsy. The findings so far indicate high levels of

B12

> > and Folate.

> >

> > I'm not sure but thought I'd heard/read somewhere that the levels of

B12

> > in the blood are not indicative of the levels of B12 in the

> > brain/nervous system (?) and that therefore if there is high levels

in

> > the blood this is not a good indicator of the B12 status as such.

I'm

> > sorry I don't know how to explain this but hope someone understands

this

> > to explain it better. And what about Folate? Would it be the same?

> >

> > I've been giving Folinic with B12 from Kirkman, so now wondering

whether

> > to discontinue/reduce.

> >

> > Any knowledge on this would be gratefully received.

> >

> > emily

> >

> >

> >

------------------------------------------------------------------------

> >

> > No virus found in this incoming message.

> > Checked by AVG.

> > Version: 7.5.518 / Virus Database: 269.21.7/1322 - Release Date:

09/03/2008 12:17

> >

>

[Guest guest]

It’s because they are not used. My son’s plasma also show too much folinic for ex and that’s because it’s not broken down and cannot integrate methylation pathway the way it should. Basically ignore mb12 and folinic in blood.

Senta

,

With all the gut problems typically demonstrated in autism, I cannot

uinderstand how a high B12 would come about....low, yes...but high???

Blood levels are NOT a strong indicator of B12. You have to look at the

type of red blood cells the bone marrow is throwing out. From memory,

the best indicator is maturity and number of RBCs This is recorded in

the CBC (Complete Blood Count......MCV etc)......Have a look into

this........This may be why there is a discrepancy betwen th OATS and

the NHS.

Scorer schrieb:

>

>

>

> We have had some blood tests done on NHS to further investigate the

> cause of ds's epilepsy. The findings so far indicate high levels of B12

> and Folate.

>

> I'm not sure but thought I'd heard/read somewhere that the levels of B12

> in the blood are not indicative of the levels of B12 in the

> brain/nervous system (?) and that therefore if there is high levels in

> the blood this is not a good indicator of the B12 status as such. I'm

> sorry I don't know how to explain this but hope someone understands this

> to explain it better. And what about Folate? Would it be the same?

>

> I've been giving Folinic with B12 from Kirkman, so now wondering whether

> to discontinue/reduce.

>

> Any knowledge on this would be gratefully received.

>

> emily

>

>

> ----------------------------------------------------------

>

> No virus found in this incoming message.

> Checked by AVG.

> Version: 7.5.518 / Virus Database: 269.21.7/1322 - Release Date: 09/03/2008 12:17

>

[Guest guest]

Can anyone post the research showing B12 conversion problems?

Sally

Senta Depuydt wrote:

>

> It’s because they are not used. My son’s plasma also show too much

> folinic for ex and that’s because it’s not broken down and cannot

> integrate methylation pathway the way it should. Basically ignore mb12

> and folinic in blood.

>

> Senta

>

>

>

>

>

>

>

>

> ,

>

> With all the gut problems typically demonstrated in autism, I cannot

> uinderstand how a high B12 would come about....low, yes...but high???

>

> Blood levels are NOT a strong indicator of B12. You have to look

> at the

> type of red blood cells the bone marrow is throwing out. From memory,

> the best indicator is maturity and number of RBCs This is recorded in

> the CBC (Complete Blood Count......MCV etc)......Have a look into

> this........This may be why there is a discrepancy betwen th OATS and

> the NHS.

>

>

>

> Scorer schrieb:

> >

> >

> >

> > We have had some blood tests done on NHS to further investigate the

> > cause of ds's epilepsy. The findings so far indicate high levels

> of B12

> > and Folate.

> >

> > I'm not sure but thought I'd heard/read somewhere that the levels

> of B12

> > in the blood are not indicative of the levels of B12 in the

> > brain/nervous system (?) and that therefore if there is high

> levels in

> > the blood this is not a good indicator of the B12 status as such. I'm

> > sorry I don't know how to explain this but hope someone

> understands this

> > to explain it better. And what about Folate? Would it be the same?

> >

> > I've been giving Folinic with B12 from Kirkman, so now wondering

> whether

> > to discontinue/reduce.

> >

> > Any knowledge on this would be gratefully received.

> >

> > emily

> >

> >

> > ----------------------------------------------------------

> >

> > No virus found in this incoming message.

> > Checked by AVG.

> > Version: 7.5.518 / Virus Database: 269.21.7/1322 - Release Date:

> 09/03/2008 12:17

> >

>

>

>

>

>

> ------------------------------------------------------------------------

>

> No virus found in this incoming message.

> Checked by AVG Free Edition.

> Version: 7.5.516 / Virus Database: 269.21.7/1322 - Release Date: 09/03/2008

12:17

>

[Guest guest]

So where does the MB12 injected go once it has gone into the bum? If it

circulates in the body the only mechanism that I can think of to do this

is the bloodstream. If B12 has to be converted into MB12 and isn't then

I can see a problem (or at least I could if I could see a conversion

mechanism problem). Anyone explain?

xx Sally

Senta Depuydt wrote:

>

> It’s because they are not used. My son’s plasma also show too much

> folinic for ex and that’s because it’s not broken down and cannot

> integrate methylation pathway the way it should. Basically ignore mb12

> and folinic in blood.

>

> Senta

>

>

>

>

>

>

>

>

> ,

>

> With all the gut problems typically demonstrated in autism, I cannot

> uinderstand how a high B12 would come about....low, yes...but high???

>

> Blood levels are NOT a strong indicator of B12. You have to look

> at the

> type of red blood cells the bone marrow is throwing out. From memory,

> the best indicator is maturity and number of RBCs This is recorded in

> the CBC (Complete Blood Count......MCV etc)......Have a look into

> this........This may be why there is a discrepancy betwen th OATS and

> the NHS.

>

>

>

> Scorer schrieb:

> >

> >

> >

> > We have had some blood tests done on NHS to further investigate the

> > cause of ds's epilepsy. The findings so far indicate high levels

> of B12

> > and Folate.

> >

> > I'm not sure but thought I'd heard/read somewhere that the levels

> of B12

> > in the blood are not indicative of the levels of B12 in the

> > brain/nervous system (?) and that therefore if there is high

> levels in

> > the blood this is not a good indicator of the B12 status as such. I'm

> > sorry I don't know how to explain this but hope someone

> understands this

> > to explain it better. And what about Folate? Would it be the same?

> >

> > I've been giving Folinic with B12 from Kirkman, so now wondering

> whether

> > to discontinue/reduce.

> >

> > Any knowledge on this would be gratefully received.

> >

> > emily

> >

> >

> > ----------------------------------------------------------

> >

> > No virus found in this incoming message.

> > Checked by AVG.

> > Version: 7.5.518 / Virus Database: 269.21.7/1322 - Release Date:

> 09/03/2008 12:17

> >

>

>

>

>

>

> ------------------------------------------------------------------------

>

> No virus found in this incoming message.

> Checked by AVG Free Edition.

> Version: 7.5.516 / Virus Database: 269.21.7/1322 - Release Date: 09/03/2008

12:17

>

[Guest guest]

we too have very high B12 in blood - 1500 I think it was and hasn't

dropped. Our paediatrician said it was due to MB12 jabs. We asked

around and were told that MB12 is a different thing but that high

serum levels show an inability to metabolise B12. But that's as far

as we got and I'm as keen as you to know any more about it. We

stopped MB12 jabs almost 2 years ago, not any ill effects, just not

enough good effects to make it worth continuing. Plus we all hated

the jabs.

>

>

>

>

> We have had some blood tests done on NHS to further investigate the

> cause of ds's epilepsy. The findings so far indicate high levels of B12

> and Folate.

>

> I'm not sure but thought I'd heard/read somewhere that the levels of B12

> in the blood are not indicative of the levels of B12 in the

> brain/nervous system (?) and that therefore if there is high levels in

> the blood this is not a good indicator of the B12 status as such. I'm

> sorry I don't know how to explain this but hope someone understands this

> to explain it better. And what about Folate? Would it be the same?

>

> I've been giving Folinic with B12 from Kirkman, so now wondering whether

> to discontinue/reduce.

>

> Any knowledge on this would be gratefully received.

>

> emily

>

[Guest guest]

Thank you all (Senta, , Sally, Natasa, , Anita and Lara)

for your replies to this. As we have just started the shots (3 so

far), I think that I will ignore the blood levels for the time being and

see where this takes us. I feel that it is worth a try especially as ds

has problems with myelin, it might just help that little bit (I really

hope so!).

thanks again!

emily

>

> >

> >

> >

> >

> > ,

> >

> > With all the gut problems typically demonstrated in autism, I cannot

> > uinderstand how a high B12 would come about....low, yes...but

high???

> >

> > Blood levels are NOT a strong indicator of B12. You have to look at

the

> > type of red blood cells the bone marrow is throwing out. From

memory,

> > the best indicator is maturity and number of RBCs This is recorded

in

> > the CBC (Complete Blood Count......MCV etc)......Have a look into

> > this........This may be why there is a discrepancy betwen th OATS

and

> > the NHS.

> >

> >

> >

> > Scorer schrieb:

> >> >

> >> >

> >> >

> >> > We have had some blood tests done on NHS to further investigate

the

> >> > cause of ds's epilepsy. The findings so far indicate high levels

of B12

> >> > and Folate.

> >> >

> >> > I'm not sure but thought I'd heard/read somewhere that the levels

of B12

> >> > in the blood are not indicative of the levels of B12 in the

> >> > brain/nervous system (?) and that therefore if there is high

levels in

> >> > the blood this is not a good indicator of the B12 status as such.

I'm

> >> > sorry I don't know how to explain this but hope someone

understands this

> >> > to explain it better. And what about Folate? Would it be the

same?

> >> >

> >> > I've been giving Folinic with B12 from Kirkman, so now wondering

whether

> >> > to discontinue/reduce.

> >> >

> >> > Any knowledge on this would be gratefully received.

> >> >

> >> > emily

> >> >

> >> >

> >> > ----------------------------------------------------------

> >> >

> >> > No virus found in this incoming message.

> >> > Checked by AVG.

> >> > Version: 7.5.518 / Virus Database: 269.21.7/1322 - Release Date:

09/03/2008

> >> 12:17

> >> >

> >

> >

> >

>

[Guest guest]

btw re myelin problems, have you tried sphingomyelin (sp?)

natasa

> >

> > >

> > >

> > >

> > >

> > > ,

> > >

> > > With all the gut problems typically demonstrated in autism, I

cannot

> > > uinderstand how a high B12 would come about....low, yes...but

> high???

> > >

> > > Blood levels are NOT a strong indicator of B12. You have to look

at

> the

> > > type of red blood cells the bone marrow is throwing out. From

> memory,

> > > the best indicator is maturity and number of RBCs This is recorded

> in

> > > the CBC (Complete Blood Count......MCV etc)......Have a look into

> > > this........This may be why there is a discrepancy betwen th OATS

> and

> > > the NHS.

> > >

> > >

> > >

> > > Scorer schrieb:

> > >> >

> > >> >

> > >> >

> > >> > We have had some blood tests done on NHS to further investigate

> the

> > >> > cause of ds's epilepsy. The findings so far indicate high

levels

> of B12

> > >> > and Folate.

> > >> >

> > >> > I'm not sure but thought I'd heard/read somewhere that the

levels

> of B12

> > >> > in the blood are not indicative of the levels of B12 in the

> > >> > brain/nervous system (?) and that therefore if there is high

> levels in

> > >> > the blood this is not a good indicator of the B12 status as

such.

> I'm

> > >> > sorry I don't know how to explain this but hope someone

> understands this

> > >> > to explain it better. And what about Folate? Would it be the

> same?

> > >> >

> > >> > I've been giving Folinic with B12 from Kirkman, so now

wondering

> whether

> > >> > to discontinue/reduce.

> > >> >

> > >> > Any knowledge on this would be gratefully received.

> > >> >

> > >> > emily

> > >> >

> > >> >

> > >> > ----------------------------------------------------------

> > >> >

> > >> > No virus found in this incoming message.

> > >> > Checked by AVG.

> > >> > Version: 7.5.518 / Virus Database: 269.21.7/1322 - Release

Date:

> 09/03/2008

> > >> 12:17

> > >> >

> > >

> > >

> > >

> >

>

[Guest guest]

Hi Natasa,

No, I haven't - what is it?

emily

> > >

> > > >

> > > >

> > > >

> > > >

> > > > ,

> > > >

> > > > With all the gut problems typically demonstrated in autism, I

> cannot

> > > > uinderstand how a high B12 would come about....low, yes...but

> > high???

> > > >

> > > > Blood levels are NOT a strong indicator of B12. You have to look

> at

> > the

> > > > type of red blood cells the bone marrow is throwing out. From

> > memory,

> > > > the best indicator is maturity and number of RBCs This is

recorded

> > in

> > > > the CBC (Complete Blood Count......MCV etc)......Have a look

into

> > > > this........This may be why there is a discrepancy betwen th

OATS

> > and

> > > > the NHS.

> > > >

> > > >

> > > >

> > > > Scorer schrieb:

> > > >> >

> > > >> >

> > > >> >

> > > >> > We have had some blood tests done on NHS to further

investigate

> > the

> > > >> > cause of ds's epilepsy. The findings so far indicate high

> levels

> > of B12

> > > >> > and Folate.

> > > >> >

> > > >> > I'm not sure but thought I'd heard/read somewhere that the

> levels

> > of B12

> > > >> > in the blood are not indicative of the levels of B12 in the

> > > >> > brain/nervous system (?) and that therefore if there is high

> > levels in

> > > >> > the blood this is not a good indicator of the B12 status as

> such.

> > I'm

> > > >> > sorry I don't know how to explain this but hope someone

> > understands this

> > > >> > to explain it better. And what about Folate? Would it be the

> > same?

> > > >> >

> > > >> > I've been giving Folinic with B12 from Kirkman, so now

> wondering

> > whether

> > > >> > to discontinue/reduce.

> > > >> >

> > > >> > Any knowledge on this would be gratefully received.

> > > >> >

> > > >> > emily

> > > >> >

> > > >> >

> > > >> > ----------------------------------------------------------

> > > >> >

> > > >> > No virus found in this incoming message.

> > > >> > Checked by AVG.

> > > >> > Version: 7.5.518 / Virus Database: 269.21.7/1322 - Release

> Date:

> > 09/03/2008

> > > >> 12:17

> > > >> >

> > > >

> > > >

> > > >

> > >

> >

>