FW: Controlling Seizures: A Nutritional Approach: glutathione etc

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Controlling Seizures: A Nutritional Approach

Dr. Freeman has written a book titled, The Epilepsy Diet Treatment:

An

Introduction to .... Seizures may also result from glutathione

peroxidase deficiency, ...

http://www.worldwidehealthcenter.net/articles-115.html

Epilepsy Foundation eCommunities Forums - GLUTATHIONE SUPPLEMENT

Things did not improve until we started giving him a glutathione ...

Tim

has idiopathic seizures, which means they don't know why he has ...

http://www.epilepsyfoundation.org/efforums/forum/messageview.cfm?

catid=9 & threadid=79851 & enterthread=y

*1: *Epilepsy Res. <javascript:AL_get(this, 'jour', 'Epilepsy

Res.');>

2000 Jun;40(1):33-9.Click here to read

<http://www.ncbi.nlm.nih.gov/entrez/utils/fref.fcgi?

PrId=3048 & itool=AbstractPlus-

def & uid=10771256 & db=pubmed & url=http://linkinghub.elsevier.com/retrieve

/pii/S0920-1211%2800%2900096-6>

Links <javascript:PopUpMenu2_Set(Menu10771256);>

Superoxide dismutase and glutathione peroxidase function in

progressive myoclonus epilepsies.

*Ben-Menachem E*

<http://www.ncbi.nlm.nih.gov/sites/entrez?

Db=pubmed & Cmd=Search & Term=%22Ben-Menachem%20E%22%5BAuthor%

5D & itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_Disco

veryPanel.Pubmed_RVAbstractPlus>,

*Kyllerman M*

<http://www.ncbi.nlm.nih.gov/sites/entrez?

Db=pubmed & Cmd=Search & Term=%22Kyllerman%20M%22%5BAuthor%

5D & itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_Disco

veryPanel.Pubmed_RVAbstractPlus>,

*Marklund S*

<http://www.ncbi.nlm.nih.gov/sites/entrez?

Db=pubmed & Cmd=Search & Term=%22Marklund%20S%22%5BAuthor%

5D & itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_Disco

veryPanel.Pubmed_RVAbstractPlus>.

Department of Neurology, Sahlgrenska University Hospital, 413 45,

Göteborg, Sweden. ebm@...

Progressive myoclonic epilepsies (EPM) are difficult to treat and

refractory to most antiepileptic drugs. Besides epilepsy, EPMs

also

involve continuous neurological deterioration. Oxidative stress is

thought to be an important factor in this process. We therefore

analyzed a series of antioxidant enzymes in the blood of patients

and compared with healthy age matched controls. In addition

patients

were given high doses of N-acetylcysteine (NAC), a glutathione

percursor to determine if symptoms of EPM would improve. Five

patients, four with EPM 1 (Unverricht-Lundborg disease) and one

patient with EPM2 (Lafora body disease) were treated with 6 g/day

of

NAC. Before treatment, plasma samples were analyzed for

glutathione

peroxidase activity, catalase activity, extracellular superoxide

dismutase (SOD) and CuZn-SOD and compared with the controls.

Erythrocyte CuZn-SOD was significantly lower in the EPM patients

compared to controls. NAC improved markedly and stabilized the

neurological symptoms in patients with EPM 1 but had a doubtful

effect in the patient with EPM 2.

PMID: 10771256

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