FW: Glutathione peroxidase deficiency and childhood seizures: selenium

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*1: *Lancet. <javascript:AL_get(this, 'jour', 'Lancet.');> 1991 Jun

15;337(8755):1443-4.

<http://www.ncbi.nlm.nih.gov/sites/entrez?

Db=pubmed & DbFrom=pubmed & Cmd=Link & LinkName=pubmed_pubmed & LinkReadableNa

me=Related%

20Articles & IdsFromResult=1675321 & ordinalpos=5 & itool=EntrezSystem2.PEnt

rez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstract>

<javascript:PopUpMenu2_Set(Menu1675321);>

<http://www.ncbi.nlm.nih.gov/pubmed/1679502?

ordinalpos=1 & itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pu

bmed_RVAbstract>*Glutathione

peroxidase deficiency and childhood seizures.*

*Weber GF*

<http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed & Cmd=Search & Term=%

22Weber%20GF%22%5BAuthor%

5D & itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbs

tract>,

*Maertens P*

<http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed & Cmd=Search & Term=%

22Maertens%20P%22%5BAuthor%

5D & itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbs

tract>,

*Meng XZ*

<http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed & Cmd=Search & Term=%

22Meng%20XZ%22%5BAuthor%

5D & itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbs

tract>,

*Pippenger CE*

<http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed & Cmd=Search & Term=%

22Pippenger%20CE%22%5BAuthor%

5D & itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbs

tract>.

Department of Biological Chemistry and Molecular Pharmacology,

Harvard

Medical School, Boston, MA 02115.

4 children with intractable seizures, repeated infections, and

intolerance to anticonvulsants had evidence of glutathione peroxidase

deficiency. 2 had low intracellular enzyme activity but normal blood

selenium and high plasma glutathione peroxidase concentrations. The

other 2 had low intracellular glutathione peroxidase activity with

low

circulating glutathione peroxidase and selenium concentrations. The

clinical state of the children improved after discontinuation of

anticonvulsant medication and selenium substitution.

Publication Types:

* Research Support, Non-U.S. Gov't <javascript:AL_get

(this, 'ptyp',

'Research Support, Non-U.S. Gov\'t');>

Comment in: Lancet. 1991 Sep 14;338(8768):700.

<http://www.ncbi.nlm.nih.gov/pubmed/1679502?

ordinalpos=1 & itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pu

bmed_RVAbstract>

PMID: 1675321

*2: *Lancet. <javascript:AL_get(this, 'jour', 'Lancet.');> 1991 Sep

14;338(8768):700.

<http://www.ncbi.nlm.nih.gov/sites/entrez?

Db=pubmed & DbFrom=pubmed & Cmd=Link & LinkName=pubmed_pubmed & LinkReadableNa

me=Related%

20Articles & IdsFromResult=1679502 & ordinalpos=4 & itool=EntrezSystem2.PEnt

rez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstract>

<javascript:PopUpMenu2_Set(Menu1679502);>

Comment on:

* Lancet. 1991 Jun 15;337(8755):1443-4.

<http://www.ncbi.nlm.nih.gov/pubmed/1675321?

ordinalpos=1 & itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pu

bmed_RVAbstract>

*Glutathione peroxidase deficiency and childhood seizures.*

*Beutler E*

<http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed & Cmd=Search & Term=%

22Beutler%20E%22%5BAuthor%

5D & itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbs

tract>,

*Curnutte JT*

<http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed & Cmd=Search & Term=%

22Curnutte%20JT%22%5BAuthor%

5D & itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbs

tract>,

*Forman L*

<http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed & Cmd=Search & Term=%

22Forman%20L%22%5BAuthor%

5D & itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbs

tract>.

Publication Types:

* Comment <javascript:AL_get(this, 'ptyp', 'Comment');>

* Letter <javascript:AL_get(this, 'ptyp', 'Letter');>

PMID: 1679502

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