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Carnitine

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Noelle,

There is so often confusion about carnitine, carnosine carnAware CarnOware. The

hot one in autism at the moment seems to be Carnosine(which is in Carnaware).

This is something I posted recently just in case it is the one you were after.

Jon.

carnitine

Someone posted an article about carnitine and I cannot find it. Could whoever

it was send it to me please? I'd really appreciate it. thanks, Noelle

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Co-Investigator, 1997 until spent, " Mitochondrial Function in Patients with

Autism. " Cure Autism Now (CAN) Research Grant. S. DiMauro, M.D., PI. Total

costs: $30,000. (ABSTRACT).

-----------------------------------------------------------------------

I would imagine they finished the study by now. Bear in mind that alot has

changed since 1997. The info below relates to the abnormalities discussed

in the Canadian CFS paper I just posted. As you'll see, the body is under

oxidative stress in CFS. It's one of the problems that comes with a chronic

illness.

Cheryl

Some of the info presented at......

AACFS Sixth International Conference on CFS, FM and Related Illnesses

January 30 – February 2, 2003

The biannual scientific conference of the AACFS was attended

by over 190 physicians and professionals from more than 14

countries.

Dr. Bob Suhadolnik of Temple University (Philadelphia) headed

up the session on biochemistry and genes. He began with an

excellent overview of biochemistry -- nitric oxide formation,

peroxynitrate, oxidative stress, elevated levels of RNaseL and

PKR, decreased acyl carnitine, and increased glutamate in

persons with CFS.

SNIP>>

Infection and Immunology was headed by Dr. Jon Hay,

SUNY/Buffalo. Dr.

Maher (University of Miami Medical School) described

the molecular basis of immunological defects found in CFS,

including activated T cells, elevated cytokines and

immunoglobulins, reduced NK cell activity, and poor delayed

skin hypersensitivity. His studies concluded that perforin and

granzymes (used by T-cells for killing other sick or infected

cells), was depressed in the T cells of persons with CFS. Also,

activation of T cells is correlated with increased IL4 and

decreased IL6, as typically seen in CFS.

Dr. Suhadolnik (see above) described the 2'-5' OAS / RNaseL

antiviral system and how the enzyme RNaseL is markedly and

persistently increased in CFS but not in control or

depressed persons.

_________________________________________________________________

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  • 11 months later...

> Is anyone familiar with this supplement? My sons OAT test came

back,

> and this was one of the many things recommended....yet the only one

> Iv never heard of. Thanks

It is an amino acid, and I have heard it can be helpful for kids with

low muscle tone problems.

Dana

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  • 5 months later...

Karyn -

I'm really bad at keeping track of websites but you can just plug in

carnaware and Lake Bluff Illinois and you'll come up with the official website

from the dr who developed carnaware.

Sherry

Karyn <KissmeKaate@...> wrote:

anyone have information on carnitine/carnaware? I have a friend with a 9 yo

autistic child, I had some information but very little. Any help is

appreciated.

~karyn

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Thanks, Sherry.......I had it somewhere, too, but heck if I can find it.

Thanks for your help~

~karyn

Re: [ ] carnitine

Karyn -

I'm really bad at keeping track of websites but you can just plug in

carnaware and Lake Bluff Illinois and you'll come up with the official website

from the dr who developed carnaware.

Sherry

Karyn <KissmeKaate@...> wrote:

anyone have information on carnitine/carnaware? I have a friend with a 9 yo

autistic child, I had some information but very little. Any help is

appreciated.

~karyn

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  • 3 weeks later...

Lori,

It is an amino acid which is used by the body to transport long chain

fatty acids to the mitochondria in your cells, where they are burned

for energy

On Sep 14, 2004, at 5:19 PM, Lori Getz wrote:

> What exactly is Carnitine?

>

> Lori Getz

>

>

>

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  • 6 months later...
Guest guest

i'm new, but i once had a doc who recommended carnaware- i don't know why- but i

just

saw that autismcoach.com carries carnaware and talks about its benefits. i'm

interested to

hear what others have to say

>

> Anyone use/have anything to share about this supplement and who stocks

> it.

> Thanks

> Aileen

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We use it. I've bought a few different brands now. NOW brand is quite

reasonable at my healthfood store, and Thorne has one also (I buy from

www.illnessisoptional.com ). There is also a prescription form of it

called Carnitor. We use it to help with energy level, and also another

form, called Acetyl-carnitine is supposed to be similar, but helpful with

the brain. We're using some of both -- can't really tell if it's helping,

but it seemed like a really good thing the first few days when we started

it. It's not that expensive, and seems to be quite safe, from my

reading. I'll know more when I stop it for a week, to see what changes then.

Terri

At 03:14 PM 3/29/2005, you wrote:

>Anyone use/have anything to share about this supplement and who stocks

>it.

>Thanks

>Aileen

>

>

>

>

>

>

>

>

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I give one of my sons Acetyl-L-Carnitine from Klaire Labs. I don't

know if I see anything. I added this along with co-q10 because I

heard it helps with mito. problems.

>

> Anyone use/have anything to share about this supplement and who

stocks

> it.

> Thanks

> Aileen

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Guest guest

Carnaware is carnosine , not carnitine....two entirely different things.

On Mar 29, 2005, at 3:25 PM, catriella1 wrote:

>

>

>

> i'm new, but i once had a doc who recommended carnaware- i don't know

> why- but i just

> saw that autismcoach.com carries carnaware and talks about its

> benefits. i'm interested to

> hear what others have to say

>

>>

>> Anyone use/have anything to share about this supplement and who stocks

>> it.

>> Thanks

>> Aileen

>

>

>

>

>

>

>

>

>

>

>

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Guest guest

What is mito? Carnitine helps fatty acid oxidation disorders. I was

wondering if any one had usedit and saw improvement in muscle tone.

Aileen

> >

> > Anyone use/have anything to share about this supplement and who

> stocks

> > it.

> > Thanks

> > Aileen

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Guest guest

Haven't used it as i'm reluctant to spend money on things without knowing

they are needed.

My son 'appeared' to have low muscle tone before we put him on the enzymes.

After 2-3 months on them, his energy level increased and the problem

disappeared. Had him assessed and the therapist told me he definitely

didn't have low muscle tone, perhaps some difficulty focusing only.

AJ

Re: Carnitine

What is mito? Carnitine helps fatty acid oxidation disorders. I was

wondering if any one had usedit and saw improvement in muscle tone.

Aileen

> >

> > Anyone use/have anything to share about this supplement and who

> stocks

> > it.

> > Thanks

> > Aileen

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Guest guest

Aileen,

Fatty acid oxidation occurs in the mitochondria of cells, hence " mito " .

My daughter takes acetyl-l-carnitine, which crosses the BBB and is

useful for brain disorders, but she does not take l-carnitine, which I

have indeed heard can be useful for muscle tone issues.

On Mar 30, 2005, at 11:41 AM, stepbystep67 wrote:

>

>

> What is mito? Carnitine helps fatty acid oxidation disorders. I was

> wondering if any one had usedit and saw improvement in muscle tone.

> Aileen

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Guest guest

>

> Anyone use/have anything to share about this supplement and who stocks

> it.

It can be helpful for low muscle tone.

It is part of the mito cocktail for kids with mito issues.

It also helps certain kids tolerate EFAs.

Dana

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my son has taken it since he has been 2 years old he is now 6 years old. It

helps him with his energy level because he has such low muscle tone he tires

fast.. We tired to take him off to see if it made a difference and it did a huge

difference..

-------------- Original message --------------

>

> Anyone use/have anything to share about this supplement and who stocks

> it.

It can be helpful for low muscle tone.

It is part of the mito cocktail for kids with mito issues.

It also helps certain kids tolerate EFAs.

Dana

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Guest guest

>

>

> i'm new, but i once had a doc who recommended carnaware-

This is carnosine [not carnitine] plus zinc. It helps some kids with

language and behaviors.

I used it [carnosine plus zinc, not Carnaware] for about 6 months for

my son.

Dana

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  • 1 year later...
Guest guest

We had Madison's blood tested to see if she was low in carnitine and she was

not. I was quite suprised becasue her tone is very low, infact the

developmentalist said she was the lowest tonedbaby she ever saw (at 3

months).Would anyone recommend giving her the carnitine?

I just don't want to keep adding more stuff as I don't know anything about

interactions.

Sharon

dianaextein <dianaextein@...> wrote:

I want to thank whoever posted about the interaction between carnitine

and EFAs. I searched

the archives but couldn't find it. Ever since I read that I started giving them

at different times

of the day. What a difference! I've never heard so much talking out of my son.

You never

know if it's just a coincidence but I've had a lot of " coincidences " when I've

tweaked

something. I just wanted to know if anyone knows how far or close I can space

the

supplements so that they don't interact. Anyone?

---------------------------------

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  • 5 months later...

/message/64370

posted this article about Creatine Synthesis Disorders

/message/61959

Article: natural sources of CARNITINE

/message/61196

Re: Carnitine Deficiency

/message/51003

carnitine is so vital that the impact on heart and key functions of

fatty metabolism etc may not be obviously clinically measurable by

just watching your child - ie in changes in speech or coordination.

My son doesn't have any obvious low tone, and his levels were

slightly low. I believe for him it has to do with the role between

EFAs and carnitine.

Here is what I pieced together:

http://www.dyspraxiafoundation.org.uk/professionals/rs_ajr.php

The predisposition to dyspraxia and related conditions may involve

mild constitutional inefficiencies of fatty acid metabolism that

increase the usual dietary requirements for HUFA. These could include

(a) poor EFA-HUFA conversion, (B) difficulties in incorporating HUFA

into brain cell membranes and/or © unusually high rates of HUFA

breakdown and loss, although there are other possible mechanisms.

Carnitine deficiency

wrote: " In addition to impacting tone (potentially)...it is a

very important component of normal fatty acid metabolism on the

mitochondria level - without which energy level will be low, and

there are other consequences...particularly to heart health, not to

mention neurodevelopment! "

Hope this helps some,

Tina

> >

> > >I understand where you're coming from. The speech related topics

are

> > >few and far between. I hesitated a couple of days ago to refer a

mom

> > >to the group because she would probably feel like she is in the

wrong

> > >place. I read very few posts anymore.

> > >

> > >

> > >

> > >

>

>

>

>

>

>

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The article I posted was on creatine, not carnitine. Is that what you

meant?

> > >

> > > >I understand where you're coming from. The speech related topics

> are

> > > >few and far between. I hesitated a couple of days ago to refer a

> mom

> > > >to the group because she would probably feel like she is in the

> wrong

> > > >place. I read very few posts anymore.

> > > >

> > > >

> > > >

> > > >

> >

> >

> >

> >

> >

> >

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