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Sue...

As far as I know goldenseal is a good herb to fight bacteria...should be

used short term, lowers blood sugar( watch out if you are

diabetic/hypoglycemic)...it does have the ability to neutralize certain

chemical compounds, so it may affect certain antibiotics...but haven't seen

any material on it. I have used it routinely in the office and have seen

only positive results when used properly.

Take care...Byron

[Lyme-aid] Goldenseal

>From: sueted@...

>

>> From: Kiana

>> I believe that the toxins are the BIG problem. I have found that

>> Goldenseal works wonders for the inflammation caused by the little

bugger's

>> toxins. I am doing a little experiment with the Goldenseal. Every time

I

>> take it -- not all the time -- I notice the next day that I feel a lot

>> stronger and better during my Herx. Yes, I just keep on Herxing and

>> Herxing, over and over again.

>>

>> I still haven't decided whether my flushing was Herx or a too fast with

the

>> Rocephin incident. But I know today that I didn't have the problem

because

>> I took Goldenseal last night. I took it tonight again so I will see what

>> happens tomorrow.

>

> I was warned by a dr (back in 1995) to avoid Goldenseal

>while on abx as it interfered with the abx. The dr used both

>conventional & alternate medicine in his practice. Unfortunately

>he is now deceased. Maybe Byron can shed some light on this issue?

>

> Sue H

>

>---------------------------

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In a message dated 7/16/99 9:21:30 AM Eastern Daylight Time,

sueted@... writes:

<< I was warned by a dr (back in 1995) to avoid Goldenseal

while on abx as it interfered with the abx. The dr used both

conventional & alternate medicine in his practice >>

funny my Dr. who is very into alternative medicine whom gave me IV Zith

reccomended goldenseal and echinacea..I have never seen anything going

against its' use with antibiotics...Bernadette

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I take Goldenseal whenever I feel like something viral is coming on,,,and it

always knocks it right out. Usually I feel alot better, and don't feel like I

am lacking the benefit of my abx. It has both antiviral, and antibacterial

properties,,,so even if it does interfere with the abx properties, it seems

to provide the same qualities itself. But one must be very careful with using

goldenseal. It cannot be taken in large quantities, or even very frequent

quantities. It can cause a host of other problems, and also lose it's ability

to remain effective. The same is not true for Echinacea, however.

Marci ( who has risen from the boxes)

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> funny my Dr. who is very into alternative medicine whom gave me IV Zith

> reccomended goldenseal and echinacea..I have never seen anything going

> against its' use with antibiotics...Bernadette

Possibly new info has come to light since the dr is now

deceased or maybe alternative medicine has differing opinions about

some herbs?

Sue H

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  • 9 years later...

The Eclectic PhysicianMedicinal Herb Monographs

Goldenseal

Botanical Name Hydrastis canadensis

Hydrastis canadensis (Golden Seal)

The information on this page compiled by Beth Burch N.D. Index (click on the keywords)

IntroductionHydrastis has been traditionally used by Native Americans to treat conditions of the mucous membranes of the respiratory, digestive and urinary tracts and also disorders of the skin and eyes. Because the root has a bright yellow color, it was also widely used as a dye. The Eclectic physicians of the 19th century used Hydrastis extensively, for a side variety of problems including as an appetite and digestive stimulant, for mouth sores, chronic gastritis and gastric ulcer, liver and gallbladder complaints, diarrhea, hemorrhoids, fissured anus, pharyngitis, nasal catarrh, conjunctivitis, otitis media and externa, muscle soreness, uterine hemorrhage, acne and eczema. King’s Dispensatory states it is specifically indicated in any chronic catarrhal state of the mucous membranes of the respiratory and digestive systems. Naturopathic physicians have long used it as a part of ’s Formula (also contains echinacea, slippery elm and other herbs) in the treatment of ulcerative conditions of the digestive tract. The success of ’s formula in the treatment of duodenal ulcer may be due to the antimicrobial effects of berberine in the Hydrastis which may act against Helicobacter pylori. Modern studies with berberine show it to be very effective in the treatment of diarrheal illness, especially those caused by bowel toxin producing bacteria. Topical use of berberine has also been shown to be effective in treating eye infections caused by Chlamydia trachomatis.

Description

Hydrastis is a member of the Ranunculaceae family, indigenous to the eastern US and Canada. It prefers undisturbed woodlands. It is a perennial herb with a knotty, creeping bright yellow root or rhizome. It has two alternate, palmate, large and lobed leaves with small white flowers. The official part is the root or rhizome.

Constituents

Isoquinoline alkaloids-hydrastine, berberine, canadine, hydrastinine

Resins

Fatty acids

Volatile oils

Action/Effects

Berberine-

Antibiotic- broad spectrum, antimicrobial against bacteria, protozoa & fungi (1)

Antiinfective- inhibits the adhesion of Streptococci to host cells (1)

Immune modulation (7)

Cholerectic- stimulates the secretion of bile

Tonic & astringent

Bitter digestive stimulant

Hydrastine-

Hemostatic

Oxytocic- stimulates the contraction of uterine smooth muscle

Conditions used for

Inflamed mucous membranes with excessive mucous production

Gastrointestinal infections with diarrhea (2,3,4)

Respiratory tract infections (1,8)

Urinary Tract Infections (5)

Infections of the eyes (6)

Enhances immune function (7)

Dosage

Because of goldenseal’s very bitter taste, many people find encapsulated or glycerin preparations easiest to take. The exception would be if taking Hydrastis as bitter digestive stimulant, then it would be preferable to use the liquid extract form.

Dried root- 500mg to 2 grams three times a day

Liquid extract- 1/2-1 teaspoon three times a day

Glycerin- 1/2-1 teaspoon three times a day

Children’s dosage- Multiply adult dosage times the child’s weight, then divide by 150.

Side Effects

Depletes B vitamins- if using Hydrastis in high doses or long term, supplement B vitamins

Possible disruption of normal bowel flora if used long term- supplement with Lactobacillus

Contraindications

Pregnancy

Infants with G6PD deficiency

Interactions with medications

Use in pregnancy & lactation

Should not be used in pregnancy until after 37 weeks due to uterine stimulant effects.

Nursing mothers with infants who have G6PD deficiency should not use Hydrastis

References

1. Sun D et al, Berberine sulfate blocks adherence of Streptococcus pyogenes to epithelial cells, fibronectin and hexadecane, Antimicrob Agents Chemother 1988;32(9):1370-4 2. Rabbani GH, Mechanism & treatment of diarrhea due to Vibrio cholerae and E. coli: roles of drugs and prostaglandins, Dan Med Bull 1996;43(2):173-85 3. Zhang MF et al, Antidiarrheal and anti-inflammatory effects of berberine, Chung Kuo Yao Li Hsueh Pao 1989;10(2):174-6 4. Rabbani GH et al, Randomized controlled trial of berberine sulfate therapy for diarrhea due to enterotoxigenic E. coli and Vibrio cholerae, J Infect Dis 1987;155(5):979-84 5. Sun D et al, Influence of berberine sulfate on synthesis and expression of Pap fimbrial adhesin in uropathogenic E. coli, Antimicrob Agents Chemother 1988;32(8):1274-7 6. Khosla PK et al, Berberine, a potential drug for trachoma, Rev Int Trach Pathol Ocul Trop Subtrop Sante Publique 1992;69:147-65 7. Rehman J, et al, Increased production of antigen-specific immunoglobulins G & M following in vivo treatment with the medicinal plants Echinacea angustifolia and Hydrastis canadensis, Immunol Lett, 1999;68(2-3):391-5 8. Gentry EJ et al, Antitubercular natural products: berberine from the roots of commercial Hydrastis canadensis powder, J Nat Prod 1998;61(10):1187-93

* The information presented in this web site is intended to inform and educate. It is not intended replace a qualified medical practitioner to diagnose or treat medical conditions.

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