Guest guest Posted July 5, 2010 Report Share Posted July 5, 2010 post on the silver list and we all respect him immensely. Perhaps this will be of value to you shha… From: blacksalveandpetswithcancer [mailto:blacksalveandpetswithcancer ] On Behalf Of rose Sent: Sunday, May 16, 2010 12:43 PM BS Subject: [blacksalveandpetswithcancer] Natural Chelation CS>Natural Chelation Bradley Thu, 17 Dec 2009 23:07:55 -0800 I believe some list members may find a significant portion of this material to be of measurable value....in their personal researches. The areas I believe to be most significant, are those dealing with the combinations of these naturally-occurring substances---for effective chelation, and avoiding fulminating Jarisch/Herxheimer's reactions. Combinations of ALA, Cilantro, and Chlorella yielded the most pronounced results....for us. Interestingly, fresh wheatgrass juice (extracted via slow-speed, gear-driven juicers), yielded favorable results almost 70% as pronounced as did the chlorella fraction. It is Dr. Greenburg's work....that we have followed most closely. Sincerely, Bradley. http://web.mac.com/medicalveritas/iWeb/Sanctuary%20Cancer%20Clinic/Natural%20Chelation.html The three most effective, safe and natural substances, when combined, create what I call the golden triangle of natural chelation. Alpha-lipoic acid (ALA), cilantro, and chlorella (which is not a chelator when used by itself), when used together and supported with strong mineral therapy, provide the ultimate in safe chelation for a broad array of heavy metals. It was the genius of Dr. Allan Greenburg who brought these three agents together for the first time and tested extensively to prove their effectiveness and safety. Alpha-lipoic acid: According to and Cherian,[10] an ideal heavy metal chelator should be able to enter the cell easily, chelate the heavy metal from its complex with metallothionein or other proteins, and increase the excretion of the metal without its redistribution to other organs or tissues. According to Dr. Lyn “ALA satisfies at least two of the above criteria; i.e., absorption into the intracellular environment and complexing metals previously bound to other sulfhydryl proteins. ALA when found unbound in the circulation, is able to trap circulating heavy metals, thus preventing cellular damage caused by metal toxicity. The fact that free ALA crosses the blood brain barrier is significant because the brain readily accumulates lead and mercury, where these metals are stored intracellularly in glial tissue.” ALA scavenges hydroxyl radicals, singlet oxygen and hypochlorous acid, can remove heavy metals by chelation and regenerates other antioxidants like glutathione, vitamin C, ubiquinol (coenzyme Q10) and indirectly, and vitamin E - as such it is an ideal chelator. A very recent study of children living in the area affected by the Chernobyl disaster also showed that ALA prevents radiation damage.[11] Alpha-lipoic acid and its cousin DHLA have justly been referred to as the " universal antioxidants " . They are active in both cell fluids and membranes, they have no serious side effects, are non-carcinogenic and do not interfere with fetus development. goes on to say, “ALA has been shown to increase both intra-and extracellular levels of glutathione in cell cultures, human erythrocytes, glial cells, and peripheral blood lymphocytes. Levels of intracellular glutathione have been shown to increase by 16 percent in T-cell cultures at concentrations of 10- 100 ìM (concentrations achievable with oral and intravenous supplementation of ALA). Increases in glutathione levels seen with ALA administration are not only from the reduction of oxidized glutathione (one of the functions of ALA) but also from the synthesis of glutathione.” Cilantro: Mobilizes toxic metals from the central nervous system and other tissues. A researcher named Dr. Yoshiaki Omura, using bioenergetic measures, discovered that some patients excreted more toxic metals after consuming a Chinese soup containing cilantro. Cilantro is the leafy part of a common herb whose seed, coriander, is a familiar culinary spice. Its active component is a mercaptan that can penetrate the blood brain barrier. Dr. Hall Cutler says that Omura is right that cilantro contains some active principle that effectively binds (and releases) mercury and crosses the blood brain barrier but says that the pharmacology or kinetics of cilantro’s active principle remains unknown. Dr. Hall has deterred people from using it for he has maintained that nobody has any clue how to use cilantro. This issue has been resolved by Drs. Greenburg and Georgiou and several others who use cilantro safely and effectively. Cilantro stimulates the body's release of mercury and other heavy metals from the brain and CNS into other tissue. Cilantro’s postulated mechanism of action is to act as a reducing agent changing the charge on the intracellular mercury to a neutral state allowing mercury to diffuse down its concentration gradient into connective tissue. Cilantro has a health-supporting reputation that is high on the list of the healing spices. Cilantro has been well-researched and has been found to have many benefits including blood sugar lowering properties,[12] anti-inflammatory properties – contains flavonoids include quercitin, kaempferol, rhamnetin, and epigenin, free radical scavenger and prevents lipid peroxidation properties,[13] and is seen as antimicrobial due to being rich in volatile oils such as carvone, geraniol, limonene, borneol, camphor, elemol, and linalool. Research by Mexican and US researchers has isolated the compound dodecanal – which laboratory tests showed is twice as effective as the antibiotic gentamicin at killing Salmonella.[14] Chlorella: Chlorella plays a particularly crucial role in systemic mercury elimination because the majority of mercury is rid through stool. Once the mercury burden is lowered from the intestines, mercury from other body tissues will more readily migrate into the intestines -- where chlorella will effectively remove it. It is the fibrous material in Chlorella that has been shown to bind with heavy metals and pesticides like PCBs that can accumulate in our bodies. Chlorella traps toxic metals in the GI tract and acts as an ion exchange resin. Chlorella is a species of unicellular fresh water algae that has been shown to possess detoxifying properties enabling it to assist or support the human detoxification system. Chlorella algae contain phytochemicals that support detoxification while the cell walls function as an ion exchange resin to absorb and retain toxic metals which can then be excreted. Chlorella is a food-like all purpose mild detoxifier (not chelator) of heavy metals. The detoxification capability of Chlorella is due to its unique cell wall and the material associated with it. The cell walls of Chlorella have been shown to have three layers of which the thicker middle layer contains cellulose microfibrils. Atkinson et al found a 14nm thick trilaminar layer outside the cell wall proper which was extremely resistant to breakage and thought to be composed of a polymerised carotene like material. Laboratory studies showed that there were two active absorbing substances - sporopollenin (a naturally occurring carotene like polymer which is resistant to degradation) and the algae cell walls. The fibrous material augments healthy digestion and overall digestive track health. Chlorella's cleansing action on the bowel and other elimination channels, as well as its protection of the liver, helps keep the blood clean. Clean blood assures that metabolic wastes are efficiently carried away from the tissues. Chlorella gets its name from the high amount of chlorophyll it possesses. Chlorella contains more Chlorophyll per gram than any other plant. Chlorella can speed up the rate of cleansing of the bowel, bloodstream and liver, by supplying plenty of chlorophyll. Chlorella and Spirulina are used as nutrient-dense foods and sources of fine chemicals in their most natural forms. They have significant amounts of lipid, protein, chlorophyll, carotenoids, vitamins, minerals, and unique pigments. They may also have potent probiotic compounds that enhance health. (You will find three chapters in Survival Medicine for the 21st Century devoted to Spirulina as a pure medicine.) Both have extensive scientific research[15] that all indicate their value for a wide range of medical situations. There are many approaches, substances, companies and doctors offering detoxification and chelation products. The great problem is finding science and in-depth studies to back up the many claims being made.[16] There is only one product named Chelorex on the market that uses the golden triangle of chlorella, cilantro and ALA and it happens to be one of the most tested natural chelation products on the market. Science Formulas has done hair, fecal and urine tests on 151 subjects and the results are impressive.[17] It fulfills the ideal of promoting excretion via multiple pathways in the body. There are several natural chelation products that use only the cilantro and chlorella to extremely positive effect supporting the basic premises being put forth here. The addition of ALA though brings in the leading work of Dr. Hall Cutler, who is one of the worlds leading experts on mercury detoxification. His extensive and successful use of ALA has won him a large devoted audience. In a large metal foundry in Russia Dr. Georgiou tested extensively many natural substances for their efficacy in removing heavy metals from the workers there and found chlorella and cilantro so effective - when used “together” - that he introduced Heavy Metal Detox (HMD) in 2005.[18] But the issues are not straight or clear cut as Dr. Georgiou explains, “During the three years that I have been researching the efficacy of certain natural substances for their heavy metal chelating effects, I have stumbled across a few surprises. For example, the literature was full of testimonials on how Chlorella and Cilantro are excellent chelators of heavy metals, so we tested both of these in carefully designed, double-blind, placebo controlled trials. Let's take Chlorella vulgaris as an example - when we tested this alone in pre-post provocation urine and feces test using 3,000 mg daily we found no difference between the pre and post tests. In other words, Chlorella by itself was not eliminating any metals that could be detected by an ICP-MS at parts per billion levels of measurement.” Georgiou continues saying, “When we looked at Cilantro we were even more surprised as there was a percentage decrease in the post-test compared to baseline. What this means was that the Cilantro not only was not eliminating metals but it was actually absorbing more metals than baseline levels. It is very probable that Cilantro, which is known as an intracellular chelator, takes metals from the interior of the cell and brings them out into the mesenchyme or extracellular space. As there is nothing to mop them up here, as the osmotic gradient increases, then you get a rush of metals from the extracellular environment into the intracellular environment. Personally, I have seen patients who were given only Cilantro by other practitioners get worse while on this protocol. Based upon the extensive double-blind placebo controlled trials that I have run with 350 people, I would strictly avoid using Cilantro by itself with no other backup.” This experience of Dr. Georgiou mirrors the warnings of Dr. Cutler about using cilantro alone or indiscriminately. Dr. Georgiou, after 3 years of research settled on a different golden triangle of natural chelation using Chlorella Growth Factor, Cilantro leaf tincture and Homeopathic energized cell-decimated chlorella vulgaris. Dr. Greenburg choice of ALA plus the addition into his formula of selenium, magnesium, zinc, vitamin C, E, MSM (Methysulfonylmethane), NAC (N-Acetyl-L-Cysteine), L-Glutamine and Taurine turns Chelorex into a complete nutritionally driven chelation prescription effective for and tested for the removal of 16 toxic metals. Much needs to be said about all of these other substances in Chelorex and we will spend some chapters on basic principles like the promotion of glutathione. A major point about successful chelation, especially of mercury, is seen in the example of the importance of selenium. The detoxifying effect of selenium on mercury toxicity is due to a formation of a biologically inactive complex containing the elements in an equimolar ratio. The complex is unable to pass biological barriers, placenta and choroid plexus and is stored in the liver and the spleen, even in the brain in a non toxic form. Mercury binds with selenium and selenium is needed for glutathione production in the cells. Mercury-selenium-glutathione interactions are crucial to anyone who wants to understand the consequences of mercury exposure and how to combat or detoxify from its poisonous effects. Sufficient magnesium levels lead to safer detoxification and chelation. In fact, it makes chelation possible. Mg-ATP provides the crucial energy to remove each toxicant.[19] Both Chelorex and HMD may not be as " powerful " as synthetic chelators such as DMSA, DMPS, EDTA etc., in the sense they do not eliminate the more narrow band of metals these synthetic chelators were designed to remove as quickly as these others when applied intravenously, but neither Chelorex or HMD have the side effects of these synthetic compounds. The main advantage of natural chelators over the synthetic ones is that they do not strip the body of essential minerals, which is common with synthetic chelators. And with the kinds of oral minerals that most doctors use today, which are not in forms that are easily absorbed by the body, this demineralization is critical. (The natural chelation protocols that are suggested in this book include raising magnesium levels with Transdermal Magnesium Therapy using magnesium chloride and concentrated sea mineral formulas to supplement orally a broad range of healing minerals.) NAC (N-Acetyl Cysteine- oral) gives so much value for the money that the need for glutathione can be met for days with this oral product. NAC (N-acetyl-Cysteine) is proven more effective than IV glutathione for acute liver toxicity Dr. Garry Gordon Synthetic chelators, especially DMSA and DMPS are actually quite toxic and one can hardly imagine using them for years. And as Dr. Jaquelyn McCandless reminds us, “Oral agents especially DMSA can encourage yeast overgrowth.” When chelating people with a heavy metal burden, particularly when they are young children or very elderly, or have any chronic disease, it is best to mobilize and eliminate the metals gently, slower than faster, so that the body can reabsorb less and avoid flooding the body with toxic metals that cause further oxidative stress due to their free radical activity. Dr. Ray, an oriental medical doctor speaks elegantly about avoiding the healing crisis that synthetic chelators so often bring. He has a product similar to HMD called NDF and NDF plus which are also based on chlorella and cilantro. MSM aids in detoxifying metals by contributing sulfur to methionine and cysteine.[20] Chelorex stands out in several powerful ways the first being the broad array of metals it will eliminate including uranium. We find this in the HMD product as well. Chelorex though contains ingredients that stimulate the human body’s natural immune defenses including its own innate ability to removal heavy metals.[21] And most importantly it gives a solid baseline of minerals that are absolutely essential for both short term and long term detoxification and chelation of toxic substances. The formula gives an important boost to the critical minerals supporting the use of a broad based sea mineral concentrate supplement, which is the best way to get ones minerals besides from foods. The individual elements found in HMD and Chelorex are all natural substances, which apart from their chelating properties have many other health benefits. Dr. Georgiou and the Russian government invested $1 million dollars in a double-blind, placebo controlled trial with 350 people that has shown its ability to safely chelate a variety of metals with natural substances that when combined work as effectively as synthetic chelators. Natural chelation is safe, non-invasive, affordable and available without prescription as it is considered food supplement. Dr. Alan Greenburg invested a small fortune also and closely studied 151 people using hair, fecal and urine tests. Together these doctors have proven conclusively the power and safety of natural chelation. The bottom line is that we want to get the heavy metals out and do that with the security that extensive studies and tests prove. In reality there is a tremendous amount of antidotal evidence with a host of chelation products and substances on the market but very little hard proof. It is far easier to make claims then to prove through heavy investments in studies. References & Notes: [1] According to tests done in the US and Japan perfluorinated chemicals (PFCs) have crept into the blood of almost every living creature in the northern hemisphere.[1] The US Environmental Protection Agency has begun an investigation to determine how a Teflon chemical has found its way into the blood of virtually every American, and polluted drinking water supplies. Perfluorooctanoic acid, a key ingredient in the making of Teflon non-stick coating for cookware can cause testicular, breast, liver and prostate cancers, as well as birth defects.[1] And in 2004 the U.S. Food and Drug Administration has found perchlorate contamination in nearly all of the more than 200 samples of lettuce and milk it collected and tested nationwide. The federal government has not yet established a standard for the perchlorate, but the Environmental Protection Agency has adopted a provisional recommendation that contamination in drinking water not exceed a range of 4 to 18 parts per billion. Perchlorate, a chemical used in rocket fuel, munitions and fireworks, can affect thyroid gland functions and lead to developmental difficulties in children. The FDA found perchlorate in 217 of 232 samples of milk and lettuce in 15 states. In 104 samples of milk, the average concentration was 5.76 parts per billion. In 128 samples of lettuce, the average concentration was 10.49 parts per billion. [2] " Most adults in the Netherlands are exposed to approximately 2 picogrammes of toxic equivalents of dioxin-like substances per kilogramme of body weight per day. In general, it may be stated that in excess of 90% of human exposure to PCDDs, PCDFs and dioxin-like PCBs derives from the consumption of animal fats, of which 50% are contained in milk and milk products. Infants are exposed to these substances before birth as well as through the maternal milk,” reported the Health Council of the Netherlands. http://www.borstvoeding.com/abon/bf_toxins.html [3] The Atlantis Mobile Laboratory, just tested in Bermuda, reported that 50 out of 70 newborns surveyed had dangerously high levels of mercury. Another study led by Mount Sinai School of Medicine in New York, through blood sampling, “found an average of 91 industrial compounds, pollutants, and other chemicals in the blood and urine of nine volunteers. The people tested did not work with chemicals on the job or live near an industrial facility. The body burden of a total of 167 chemicals found in the volunteers, showed 76, which cause cancer in humans or animals, 94, which are toxic to the brain and nervous system, and 79 that cause birth defects or abnormal development. The dangers of exposure to these chemicals in combination have never been studied. Body Burden. National Report on Human Exposure to Environmental Chemicals. http://www.oztoxics.org/cmwg/body%20burden/international.html [4] Heavy metal poisoning has become an increasingly major health problem, especially since the industrial revolution. Heavy metals are in the water we drink, the foods we eat, the air we breathe, our daily household cleaners, our cookware and our other daily tools. A heavy metal has a density at least 5 times that of water and cannot be metabolized by the body, therefore accumulating in the body. Heavy metal toxicity can cause our mental functions, energy, nervous system, kidneys, lungs and other organ functions to decline. [5] “Data from the CDC tells us that children are carrying around more phthalates and certain pesticides in their bodies than adults and that woman have more mercury and some other toxic chemicals in their bodies than men. This is very disturbing because children and babies in utero have some of the highest risks of adverse health impacts, " said Charlotte Brody, RN, executive director of Health Care Without Harm. [6] The World Wildlife Fund (WWF) visited 13 locations in England, Northern Ireland, Scotland and Wales in the summer of 2003 and took blood samples from 155 volunteers. Lancaster University analyzed the samples for 78 chemicals. 12 organochlorine pesticides (including DDT and lindane), 45 PCB congeners and 21 polybrominated diphenyl ethers (PBDE) flame retardants, including those found in the commercially traded penta-, octa- and deca-BDEs. Their FINDINGS:[6] • Every person tested is contaminated by a cocktail of known highly toxic chemicals which were banned from use in the UK during the 1970s and which continue to pose unknown health risks. • We found 70 (90 per cent) of the 78 chemicals we looked for in the survey. The highest number of chemicals found in any one person was 49, nearly two thirds (63 per cent) of the chemicals looked for. • Every person is contaminated by chemicals from each group: organochlorine pesticides, PCBs and PBDEs (flame retardants). • The highest concentration of any chemical found was 2,557 ng/g (ng/g. parts per billion) of the DDT metabolite pp.-DDE. The use of DDT was banned in the UK more than 20 years ago. • The most frequently detected chemicals were PCB congeners 99 and 118 and the DDT metabolite pp.-DDE, which were detected in all but one of the 155 volunteers. • Ten chemicals were found in more than 95 per cent of volunteers [7] http://www.gordonresearch.com/answers/chlorella_and_cilantro.html [8] The earliest types of chelation involved synthetic agents such as BAL, penicillamin e and EDTA administered intravenously for acute toxic metal poisoning. Subsequently, DMSA and DMPS were utilized, first intravenously and later orally and now even transdermally. Chelation therapy provides a relatively safe, effective, and inexpensive alternative to the drugs and surgery often used for circulatory disorders such as coronary heart disease, carotid (neck artery) stenosi (blockage), and leg artery stenosis (blockage).[8] Chelation is a process by which toxic substances in the body, particularly heavy metals can be excreted safely. However, numerous negative side effects are associated with each of these chelators (with the exception of EDTA which is ‘relatively’ safe[8]) including allergic reactions involving the skin and mucous membranes (itching, exanthema or rash), as well as occasional cases of s- Syndrome or erythema exudative multiforme.(11). Other side effects include nausea, headache, muscle aching, changes in taste, severe malaise, dizziness, numbness, insomnia, diarrhea, weight loss, extreme fatigue, leg cramps, cardiac arrhythmia, liver and kidney damage, abdominal pain, anxiety, severe restlessness, mental changes, tremors, inability to concentrate, poor memory, impaired equilibrium, chemical sensitivities and tinnitus. (12). Studies have shown up to 30% of patients have severe negative side effects as a result of these synthetic chelating agents, which may develop after a single dose. For warnings against DMPS all one has to do is go to the DMPS Backfire website. [9] R. A. Goyer, M. G. Cherian, M. M. , and J. R. Reigart. Role of Chelating Agents for Prrevention, Intervention, and Treatment of Exposures to Toxic Metals. Environmental Health Perspectives Volume 103, Number 11, November 1995 [10] MM, Cherian MG. The search for chelate antagonists for chronic cadmium intoxication. Toxicology 1990;62:1-25. [11] Korkina, L.G., et al. Antioxidant therapy in children affected by irradiation from the Chernobyl nuclear accident. Biochem. Soc. Trans., Vol. 21, 1993, p. 314S [12] Gray AM, Flatt PR. Insulin-releasing and insulin-like activity of the traditional anti- diabetic plant Coriandrum sativum (coriander). Br J Nutr 1999 Mar;81(3):203-9. [13] Chithra V, Leelamma S. Coriandrum sativum changes the levels of lipid peroxides and activity of antioxidant enzymes in experimental animals. Indian J Biochem Biophys 1999 Feb;36(1):59-61. [14] Delaquis PJ, Stanich K, Girard B et al. Antimicrobial activity of individual and mixed fractions of dill, cilantro, coriander and eucalyptus essential oils. Int J Food Microbiol. 2002 Mar 25;74(1-2):101-9. [15] http://www.mercola.com/chlorella/research.htm [16] In the area of chelation we have many companies making claims. For example a product released by Dr. Eliaz of modified citrus pectin and dietary alginate claims, " Not only that, Pectasol® is the only chelator of its kind that’s been shown to eliminate toxic heavy metals and other dangerous substances on humans. A recent pilot clinical trial – in which patients were tested for 20 different toxic elements and minerals – showed dramatic results. " The data of the (Pre clinical results) found at http://dreliaz.com/abstracts_detail.php?result_set=1 & ingred=30 & abs=939 shows increased urinary excretion over 6 days of 3 metals (arsenic, mercury & cadmium) not 20 as advertised and does it with a small group over a short period of time. Comparing this study to Science Formulas’ Chelorex 4yr study or to Dr. Georgiou’s studies in Russia is just not possible. There are many products available and the choices are bewildering. Words are easily said and written but when it comes to removing heavy metals it is very important to know what a product can do. [17] [18] http://mercuryexposure.org/index.php?article_id=648 [19] Magnesium ions constitute the physiologically active magnesium in the body; they are not attached to other substances and are free to join in biochemical body processes.5 This is one basic reason magnesium helps to detoxify toxic chemicals and helps eliminate heavy metals from the body. Another reason would be the part it plays in glutathione production but undoubtedly, as Dr. Haley indicates, the Mg-ATP provides the crucial energy to remove each toxicant. A magnesium ion is an atom that is missing two electrons, which makes it search to attach to something that will replace its missing electrons so it is actively and directly involved in diminishing heavy metal toxicity. Magnesium appears to be a competitive inhibitor of lead and cadmium. An increased level of magnesium has been shown to eliminate lead and cadmium through the urine and has also been reported to reduce the toxic effects of aluminum. [20] MSM (methylsulfonylmethane): Enhances permeability of cell membranes and is believed to enhance detoxification by increasing the permeability of cell walls. MSM is a naturally occurring sulfur containing molecule found in fruits, vegetables, seafood and meat. It is present in the body and humans excrete from 4-11 mg. daily in urine. Research suggests that it is required for the body to preserve normal function and structure. Food processing destroys the MSM normally present in food. [21] Cysteine and cystine are closely related. One cystine molecule is composed of two bonded cysteine molecules and each can convert to the other as required. Both amino acids contain sulfur (via free sulfhydryl groups) which makes them powerful antioxidants. The acetylated form of cysteine is N-acetylcysteine (NAC) and contains a bonded acetyl group. In this form, NAC is more easily absorbed, more stable, and safer to use than cysteine on its own, which can be neurotoxic in very high doses. NAC is effective at promoting glutathione synthesis. This amino acid " combo " incorporates cysteine, glutamic acid, and glycine and has powerful antioxidant and immune stimulating properties. Some studies have shown that supplementing with NAC yields higher glutathione levels than supplementing with cysteine or glutathione directly. Cysteine is found in alpha-keratin, the main protein of fingernails, toenails, skin, and hair. Quote Link to comment Share on other sites More sharing options...
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