Oral Glutatoines boost my son's speech yet no adversed reactions as MB12 shots brought to my son

[Guest guest]

Hi, Sue,

After I studies your several emails regarding Glutathione's functions of detoxification, reducing inflammation, boost immun, etc... I went to our local health food store and bought oral glutathione, I had my son try it, per the instruction, 50mg per day for adult, so I gave my son half of the amount per day, it has been 3 days now, and he has been displaying extraordinarily calm, and his language obviously is getting clear and clear everyday, and he started to use more complex sentances and content is getting more and more complicated... my husband and i are very excited to share the good news with you and the rest of the group. We are still using oral, not quite sure it 25mg per day for my son weighs about 70lbs is enough, we have not used the patches yet, just in the trial period by oral.. and glutathione alreayd deliver the result. Something about glutathione that i prefer overl MB12 shots is Glutathione does bring the same result and progress in

language improvement, but, it does not cause hyperactivity and stimming as much as MB12 shots gave my son, on the contrary, Glutatione calm my son and reduce anxiety level almost 200%. It has only been 3 days. No shots, no patches, only by oral and it shows results.Another thing that I have noticed, glutatoine helps me and husband sleep better, and I can see my son's calmness and clear speech come from reduction of his brain inflammation. ( Everytime we gave my son motrin, he reacts like this, calm and well spoken.)

Now, I am seriouly thinking about trying the other stuff you have mentioned---L Carnosine patches, that repairs the deep frontal part of the brain (entorhinal

cortex) cortex in the brain and improve language, social awareness, and calmness.

However, how do I order them? It seems i have to become their members or i need some kind of distributor ID? Can you adivse me?

The reason why I like to try the patches of Carnosine is because my son is currently taking numeric of supp and I would like to him to take a break from swollowing pills every morning, wearing patches may be a good idea.

Sincerely, Rei Founder/Senior Loan Officer

TX State Mortgage Broker License #75036 TX State Loan Officer License #65838 Miles Funding LLC

Rethink Vaccines. Reverse Autism.

Subject: B... CARNOSINE for Spectrum disorders and Seizures,etc.To: milesfunding@...Date: Thursday, July 3, 2008, 2:05 PM

Here's how Carnosine helps ASD..

Hi from Sue,

While Carnosine is most known for it's antiglycation.."turning old cells into new cells"

associated with anti-aging benefits... it has numerous neurological benefits as

Dr. Chez found for children with ASD in his double blind studies summarized below.

Note the benefits for seizures as well.

I find that the YAGE LW Carnosine patch helps me with my memory, focus, getting things done

and motivation...not to mention it's wonderful rejuvenation of cells due to getting

rid of metabolic wastes !...

I also have a study showing it killed all 7 types of cancer found in a Petri dish.

so we use it for our dog's cancer recovery along with the GSH patch.

Hope this helps,

Sue

See below for summaries on studies..

L - C A R N O S I N EWhat is Carnosine?

The naturally-occurring amino acid is found within the human body, a by-product of

proteins digested within the body. The deep frontal part of the brain (entorhinal

cortex) is believed to be a site where carnosine tends to accumulate. It may

interact with zinc in that area, as well as having effects on GABA, a brain

neurotransmitter, which by a complex chemical reaction forms homo-carnosine.What Studies Have Been Done with Carnosine?Rat and animal studies have been done with carnosine looking at "neuroprotection."

These investigations aimed to examine protective action since carnosine may be

protective of muscle and nervefunction. There have been no studies that have shown

any evidence of toxicity or teratogenicity in animals where carnosine has been

studied. Few scientifically-validated human studies have been conducted, however,

and most of the information one finds about carnosine's claims are of the quality

found on the internet. Claims have been made for generic carnosine/carnosine

formulations aiding in combating a range of maladies from Alzheimer's to body

building.Why Carnosine, then?Recent MRI studies by Petroff and colleagues (2001) examining levels of brain

chemistry showed a relationship between homo-carnosine and GABA in temporal

lobe and generalized myoclonic epilepsies. These authors described homo-carnosine

levels that may correlate with seizure control even when GABA response is defective

in human studies. Dr. Chez was intrigued by the results of this study, and thus began

a study in June, 2001 that aimed to test if supplementing carnosine orally could

enhance seizure protection in children who were already on anticonvulsants and who

had recurrent seizures despite being on standard drug therapy. He hypothesized that

the addition of carnosine could decrease seizure frequency and so began an

open-label study of carnosine which he acquired via an industrial chemical company.The Open-Label StudyA total of 75 children, who had "failed" multiple antiepilepticmedications in an effort

to stop their seizures (including steroids and the Ketogenic diet) with histories of

partial or generalized epilepsy entered the open-label study. The majority had

fronto-temporal lobe seizures, or generalized epilepsy. Approximately 25% had EEGs to

directly compare before and after starting the carnosine. Many patients had

reductions in seizure frequency, but without EEG correlation. Two sisters with

hypsarrythmia/Lennox-Gastaut variant both showed dramatic improvements

in EEG amplitude, spike frequency, and background activity. In three other patients with

primary or secondary generalized spike and wave patterns or Lennox-Gastaut type

patterns, EEG amplitude and spike frequency improved with carnosine in dosages

of 800-2,000 mg. per day. Dosage was titrated upward depending upon bodyweight.

No side effects were reported.Unexpectedly, parental diaries showed a pattern of

comments related to gains in cognitive domains including language, alertness,

energy levels, and even gross motor ability. Dr. Chez was motivated by such reports

in addition to comments from other professionals that worked simultaneously with

the children (e.g., speech therapists) who, unaware that children were on the new

supplement, spontaneously stated that individual children were showing incremental

gains not previously seen. Expressive language was described as more fluent, eye

contact more frequent, and interest in the environment was more prominent.

Dr. Chez thought that this supplement could be of benefit to children with autism or

PDD and so began to give it to children with such diagnoses in an open-label trial.

Indeed, parents reported benefits in their children after as few as 2 weeks, in the

areas of socialization, expressive language, alertness level, energy level, adaptation

to change, and curiously, gross motor planning.The Double-Blind StudyBecause of the remarkable cognitive improvements in language, speech production

and school performance as well as social alertness, Dr. Chez felt it important to

study the effect of the supplement in children with Autistic Spectrum Disorders.

Children were included in this study if they had histories of abnormal EEG, and

had previously responded to cognitive-enhancing dementia medications (as part of a

controlled study at the office) or to anti-convulsants. A double-blind placebo

controlled study with carnosine was begun. Children were randomly placed on either

active carnosine or placebo. Expressive and receptive language measures, two

autism rating scales, and parent rating analog scales were administered at the start

and completion of the study. Results of this study indicated clinically meaningful

changes in many aspects of autistic features, and also showed that the carnosine

supplement improved children's expressive and receptive language significantly. This

is the only dietary supplement to date studied in a double-blind fashion in autism.Who Benefits and What are the Side Effects?The majority of children with either epilepsy or autism treated in open label studies

by Dr. Chez benefited from carnosine supplementation. Dr.Chez estimates that

approximately 10% of children who have been on the carnosine supplement have

had reports of no improvement. A very small percentage (less than 5% of children

with epilepsy or autistic spectrum disorders) have shown increased physicalhyperactivity or verbal hyperactivity, but we are unable to ascertain if these reports

are directly related to the carnosine supplement. No sleep disturbances were

reported as a result of carnosine therapy even in dosages up to 3,000 mg. a day.

No abdominal side effects, skin rashes, or any changes in anticonvulsant blood

levels, liver functions or hematological studies. No patients had any urinary changes

or bowel habit changes from the carnosine.Many children on the autistic spectrumwere reported to increase their range of food choices with an improved range ofappetite.Responses have been seen in generalized epilepsies, focal seizure

disorders, autism, PDD, and head injury to date. Because of its effect on entorhinal

cortex, improvements in Alzheimer's disease or other frontal lobe encephalopathy may

be possible. Any syndrome that involves apraxia or expressive language delay maybenefit from this. Concurrent studies are currently being run or planned in areas ofattention disorder, Tourette's syndrome, and various learning disability syndromes of

the nonverbal type.