A Good Article About EN with reference to Immune cell clusters and symptoms

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Click Here for the EN Article Symptoms

The symptoms of erythema nodosum include:The skin on the shins is most commonly affected.Other areas that may be affected include the ankles, calves, thighs, buttocks and arms.Raised, red, hard, hot and painful lumps appear on the skin.The lumps can be from 1cm to 20cm wide.Up to 50 lumps may develop in the affected area.Leg swelling.Fever and general malaise.Around half of all cases are associated with joint pains, particularly the knees.Conjunctivitis sometimes develops.The lumps turn from bright cherry red to purple over a few days.The purple lumps become brownish-yellow and flat over a few weeks.The lumps tend to recur if the person doesn't have sufficient rest.Pockets of immune cells

The skin consists of three main layers: the epidermis, the dermis and

the subcutaneous layer. The subcutaneous layer is the deepest, and

provides support and structure for the overlying dermis and epidermis.

Erythema nodosum is an immunological response. The characteristic lumps

are collections of immune cells clustered in pockets within the

subcutaneous layer. In some cases, the dermis (middle layer of the

skin) may also be affected.

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thanks for this article. I was looking for a good article for Tom to reqad about this disease. Sharon Strecker wrote: Click Here for the EN Article SymptomsThe symptoms of erythema nodosum include: The skin on the shins is most commonly affected. Other areas that may be affected include the ankles, calves, thighs, buttocks and arms. Raised, red, hard, hot and painful lumps appear on the skin. The lumps can be from 1cm to 20cm wide. Up to 50 lumps may develop in the affected area. Leg swelling. Fever and general malaise. Around half of all cases are associated with joint pains, particularly the knees. Conjunctivitis sometimes develops. The lumps turn from bright cherry red to purple over a few days. The purple lumps become brownish-yellow and flat over a few weeks. The lumps tend to recur if the person doesn't have sufficient rest.Pockets of immune cellsThe skin consists of three main layers: the epidermis, the dermis and the subcutaneous layer. The subcutaneous layer is the deepest, and provides support and structure for the overlying dermis and epidermis. Erythema nodosum is an immunological response. The characteristic lumps are collections of immune cells clustered in pockets within the subcutaneous layer. In some cases, the dermis (middle layer of the skin) may also be affected.