Anxieties / Thyroid problems/ LOD may help

[Guest guest]

Hi From Sue,

Also keep in mind...the thyroid is a place oxalates

are known to collect in addition to the kidney and since it appears that thyroid function

can be compromised by oxalates,

a LOW oxalate diet may help anxieties as well.....

http://www.lowoxalate.info/research.htmlAm J Clin Pathol. 1987 Apr;87(4):443-54.Calcium oxalate crystals in the thyroid. Their identification, prevalence,origin, and possible significance.Reid JD, Choi CH, Oldroyd NO.Calcium oxalate crystals are not encountered in normal animal tissues, exceptfor the human thyroid, where they were found in 79 of 100 routine consecutiveautopsies. They appear during childhood, and numbers of crystals increase withage. In diffuse hyperplasia, prevalence was higher, but crystals were fewer thanexpected. In adenomas and carcinomas, crystals were decreased except for threecases with a striking focal increase. None was found in 22 adult primatethyroids. After Clorox digestion of human thyroids, calcium oxalate dihydratewas identified by x-ray diffraction and infrared spectroscopy. Origin, tissueand species localization are discussed in relation to ascorbate metabolism,thyroperoxidase, and calcitonin. Possible metabolic roles are suggested. Calciumoxalate crystals injected in animals and humans initiate a foreign body reactionwith giant cells. In Hashimoto's thyroiditis, crystals disappear butoccasionally remain with giant cell reaction. In subacute thyroiditis,granulomas are related more to colloid than to crystals.PMID: 2435146 [PubMed - indexed for MEDLINE]Am J Surg Pathol. 1993 Jul;17(7):698-705.Birefringent (calcium oxalate) crystals in thyroid diseases. Aclinicopathological study with possible implications for differential diagnosis.Katoh R, Kawaoi A, Muramatsu A, Hemmi A, Suzuki K.Department of Pathology, Yamanashi Medical University, Tamaho-cho, Japan.To elucidate the nature and significance of calcium oxalate crystals in thepathologic thyroid, we used polarized light microscopy to review 357 thyroidlesions. Under polarized light, calcium oxalate crystals had brilliantbirefringence, and they were invariably identified within the colloid offollicles. The highest prevalence of crystals (87.9%) was in nodular goiters;they were also found in 60.0% of follicular adenomas and 33.3% of follicularcarcinomas. The prevalence of crystals in papillary carcinomas was very low(5.4%). Therefore, the overall prevalence was 69.4% in benign nodules and 7.6%in malignant nodules. A heavy deposit of crystals was seen only in benignnodules except for one case of follicular carcinoma. Graves' disease, focalthyroiditis, and subacute thyroiditis showed low prevalence: 25.0, 46.9, and40.0%, respectively. In cases of toxic nodules, the crystals were sparselyidentified within nodules, but abundantly observed in surrounding inactivetissues. Immunohistochemistry for thyroid hormones confirmed that the crystalstended to appear in inactive follicles. On tissue x-ray film, the crystalsappeared as microcalcifications. As a result of these findings, we suggest thatexaminations of crystals are likely to be useful in the differential diagnosisof thyroid diseases and in possible estimations of the functional state oflesions.PMID: 8317610 [PubMed - indexed for MEDLINE]J Pediatr. 2000 Feb;136(2):255-7.[] LinksHypothyroidism in primary hyperoxaluria type 1.Frishberg Y, Feinstein S, Rinat C, Drukker A.Division of Pediatric Nephrology, Shaare Zedek Medical Center and Hebrew University, Haddasah Medical School, Jerusalem, Israel.We describe 4 patients, aged 3 months to 23 years, with end-stage renal disease and severe, symptomatic hypothyroidism. All 4 had primary hyperoxaluria type 1 (PH1) with diffuse tissue (kidneys, skeleton, eyes, heart) calcium-oxalate deposition, a condition known as oxalosis. The hypothyroidism responded to thyroid hormone replacement therapy. Clinical hypothyroidism within the framework of PH1/oxalosis was probably caused by thyroid tissue damage from an abundance of calcium oxalate. We recommend that thyroid function be monitored in patients with PH1 and oxalosis.PMID: 10657836 [PubMed - indexed for MEDLINE]