Valtrex as an adenosine modulator

July 3, 2008

Hi

I am an adult with CFS and I'm fairly new to this list.

I'm following the DAN/Yasko protocols since I am convinced by the

work of Rich Van Konynenburg that I have glutathione depletion

secondary to a methylation block & I think the protocols address the

root causes of my illness.

OK, so that's my introduction. Here's my question.

I'm on Valtrex for high IGG EBV titers.

But most of my reaction to Valtrex is above the neck.. that is to say

cognitively. It's like someone turned the dimmer on the light switch

up a bit.

I've been on transfer factor before for EBV and the response was

quite different...fatigue.. lethargy etc. In other words, the kind of

symptoms you might associate with an immune reaction.

I've read Stan's thoughts on Valtrex as an adenosine modulator on the

TACA page & I've looked at archived posts on the subject on this site.

I've also read Deth's book " The Molecular Origins of Human

Attetion - The Dopamine/Folate Connection " where he talks about

elevated levels of adenosine in autism and other conditions.

He also talks about elevated levels of adenosine inhibiting dopamine-

stimulated phospholipid methylation .. a mechanism which is critical

for attention..and attention-based learning.

So what I'm wondering is:

Do DAN! doctors track this action of Valtrex?

Are they running tests looking @ how Valtrex impacts adenosine levels?

A lab called Vitamin Diagnostics in NJ certainly measures plasma

adenosine.. maybe others do too.

Is it dangerous to monkey around with this mechanism.. given that

adenosine levels are supposed to fluctuate on a 24-hr cycle?

Also, FWIW, I noticed that my pupils got fixed and dilated on Valtrex

like I was on speed, and I was a bit of an energiser bunny, but focus

was not improved.

Maybe I was taking too much Valtrex. I started at 3grams a day and

halved it since then.

And of course, I am kind of assuming the same thing is going on in

Chronic Fatigue Syndrome as autism...A big if...

Anyhow, any feedback appreciated.

Cheers

L.

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