Cutaneous Reactions to Antibacterial Agents

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Cutaneous Reactions to Antibacterial AgentsClick above to read the entire article and view many "rashes" that might be confused with EN.Drug-Induced Erythema NodosumErythema nodosum is a cutaneous reaction pattern. It is characterized by tender, subcutaneous, erythematous nodules usually located on the anterior surface of the legs and occasionally elsewhere (Figure 8). Histologic examination of a wedge-biopsy specimen of a suspected lesion reveals a septal panniculitis. Erythema nodosum caused by drugs is not distinguishable from that due to other factors. Erythema nodosum usually regresses spontaneously in a few weeks.Figure 8. Tender erythematous nodules on the knees and anterior surface of the legs. Treatments include bed rest or elastic bandages and a nonsteroidal anti-inflammatory agent. For persisting lesions, saturated solution of potassium iodide 400-900 mg daily may be helpful.[25] See Table for antibacterial drugs causing erythema nodosum.Table. You can help Erythema Nodosum Research. Just go to www.goodsearch.com and under the I'm Supporting section enter Erythema Nodosum Research Fund. Every time you use Goodsearch to search, a penny will be donated to EN Research. So sign up today, and be sure to tell your friends, family and co-workers. Let's find a cure for Erythema Nodosum!

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