This Is Why Hypos Get Colder Easier

[Guest guest]

Or maybe even hotter at times, depending on environment and rapid changes? It's because we all take one set amount of hormone, trying to imitate the original feedback loop, and it just isn't the same, but is the best we can do at this time in history. The thyroid gland itself used to respond to these tiny microscopic ebbs and flows, but just won't do that any more, when it has to be taken out of the picture and substituted with manmade thyroid hormones.

http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=endocrin & part=A290#A290

From: Endocrinology---An Integrated Approach----S.S. Nussey and S.A. Whitehead

"This regulatory loop is affected by internal and external factors that alter the rate at which TSH is secreted. It is secreted in a pulsatile fashion with a diurnal variation, peaking around midnight. Environmental temperature may stimulate or inhibit the release of TSH by adjusting TRH secretion. Thus, after 24 h exposure to a cold environment, the plasma concentrations of thyroid hormones increase with a consequent rise in basal metabolic rate and an increase in the endogenous production of body heat. This effect is more marked in rats than humans."

Note that there is a whole lot more on these pages concerning all of this, but this was just a short exerpt from it.

S. (Lilacs)