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On Mon, 2 Dec 2002 19:03:30 -0500 (Eastern Standard Time), Sharon

wrote:

>I am currently reading with great interest the informationÿ on Midecol CF.ÿ

I just uploaded some two additional files on Midecol CF into the

Preservative Info folder.

Midecol CF Patent - Intro and Claims.pdf

Midecol CF - Information and Literature Summary.pdf

Maurice

--------------------------------------------------------

Maurice O. Hevey

Convergent Cosmetics, Inc.

http://www.ConvergentCosmetics.com

-------------------------------------------------------

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So is it to early to have a decision rendered on Midecol CF? The research

and everything else is very promising - from my very layman's eyes.

Yoki

I cried unto the Lord with my voice,and he heard me out of his holy hill.

Selah

Midecol CF

On Mon, 2 Dec 2002 19:03:30 -0500 (Eastern Standard Time), Sharon

wrote:

>I am currently reading with great interest the informationÿ on Midecol CF.ÿ

I just uploaded some two additional files on Midecol CF into the

Preservative Info folder.

Midecol CF Patent - Intro and Claims.pdf

Midecol CF - Information and Literature Summary.pdf

Maurice

--------------------------------------------------------

Maurice O. Hevey

Convergent Cosmetics, Inc.

http://www.ConvergentCosmetics.com

-------------------------------------------------------

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my really quick skimming of the info provided would lead me to

say " no " . There were several instances where the degree of

preservation didn't meet established parameters, most noticeably in

cosmetic cream. Whether the BP parameters are relevant or not, I

can't say...

There was also no mention that I could see of the pH range in which

it was stable, although there was mention that the fatty acids would

saponify in an alkaline base (which, frankly, could really mess up a

product's consistency). Also nothing I saw on temperature stability,

although I could have missed that.

Admittedly, I read through it very quickly, but didn't see anything

on whether or not it had been descented. Neem oil REEKS, and if

they're recommending a 1% add rate of this stuff, it had better not

have a characteristically neemy odour!

My other serious concern would be with the fact that this IS

a 'natural' product and therefore the efficacy of the product would

vary from batch to batch (this is mentioned just before the

literature citations). This to me means that the variation in

efficacy could vary dramatically from batch to batch, which would be

a very serious concern to me.

I think I'll stick with Germaben II & Phenonip! *grin*

Jules, who really is going to go back to the books for another hour

or so...

> So is it to early to have a decision rendered on Midecol CF? The

research

> and everything else is very promising - from my very layman's eyes.

> Yoki

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Aside from the fact that neem stinks - I will have to take your word for it -

isn't it true that when using a natural preservative that you may not

necessarily use that standard ratios of .2% - 1%. Remember, the synthetics you

have to because they were engineered that way so as not to damage the product

nor the person. Let's face it, in too large of an amount all of the synthetics

would kill us or make us so sick that we would wish that we were dead.

If we say that for example the ratio for natural preservatives is around 5%,

would not that then begin to offer some protection? when you get a chance to

really look at the info, it says that at 1% it began to provide the treatment

that was necessary in most of the products it was tested. So at probably a

higher rate, then it would be doing comparable to the synthetics. Now the fact

that neem stinks, I am sure that they could deodorize it; much like they do for

cocoa butter.

I will defer to your judgement as to the pH of the product. I would not even

began to hazard a guess at that. But let us say that all other variables were in

place, would not upping the percentage of the natural preservative do the job

sufficiently?

Just a thought?

Yoki

I cried unto the Lord with my voice,and he heard me out of his holy hill.

Selah

Re: Midecol CF

my really quick skimming of the info provided would lead me to

say " no " . There were several instances where the degree of

preservation didn't meet established parameters, most noticeably in

cosmetic cream. Whether the BP parameters are relevant or not, I

can't say...

There was also no mention that I could see of the pH range in which

it was stable, although there was mention that the fatty acids would

saponify in an alkaline base (which, frankly, could really mess up a

product's consistency). Also nothing I saw on temperature stability,

although I could have missed that.

Admittedly, I read through it very quickly, but didn't see anything

on whether or not it had been descented. Neem oil REEKS, and if

they're recommending a 1% add rate of this stuff, it had better not

have a characteristically neemy odour!

My other serious concern would be with the fact that this IS

a 'natural' product and therefore the efficacy of the product would

vary from batch to batch (this is mentioned just before the

literature citations). This to me means that the variation in

efficacy could vary dramatically from batch to batch, which would be

a very serious concern to me.

I think I'll stick with Germaben II & Phenonip! *grin*

Jules, who really is going to go back to the books for another hour

or so...

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> Aside from the fact that neem stinks - I will have to take your word for

it - isn't it true that when using a natural preservative that you may not

necessarily use that standard ratios of .2% - 1%.

Neem stinks to the High Heaven. Be careful about quoting standard ratios for

preservatives, it depends on the preservative and the formula.

>Remember, the synthetics you have to because they were engineered that way

so as not to damage the product nor the person. Let's face it, in too large

of an amount all of the synthetics would kill us or make us so sick that we

would wish that we were dead.

Preservatives are designed to kill micro organisms. Logic would seem to

dictate that if used in large enough amounts that they would kill or injure

larger species. Just because a preservative is " natural " is no indication

that it would act any differently than a synthetic preservative. I would

have thought that most people on this list would know that natural does not

necessarily mean safe. If you look at allergies, it looks like people are

allergic to the natural more than the synthetic. With the increased use of

essential oils, more and more people are becoming sensitized to those oils.

Recently, I have read about problems in Australia with Tea Tree oil, this is

an oil that many in the US were using neat, and probably still are.

I would like to see a natural preservative, but I wouldn't count on it being

the Holy Grail. It would need to be effective in cosmetics, easy to

incorporate, and not stink. Even then I would want to see a track record

before I ever used it. Some people thought Myavert C was the answer until

one of the larger natural companies had to recall their products because it

failed. Right now you can make a product that is over 99% natural without

taking unnecessary risk. If you consider the parabens natural (which

technically you could because they come from the earth) you could make some

products that are 100% natural.

Pat.

Peace, Joy, Serenity

House of Scents tm. Body Oils, Fragrance Oils, Incense, Candles, Soap, Etc.

pat@...

http://www.houseofscents.com/

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<. I would

have thought that most people on this list would know that natural does not

necessarily mean safe.>

Pat -

Did not mean to insult the " list " with my obviously sophomoric question. But

that is MY belief. I do not doubt that natural products can be just as lethal as

the synthetics that are produced. I have seen that more than enough times to

know, however, if given a choice, I would much rather use the natural than the

synthetic. I won't have to worry about an 'unknown' side effect that will never

be known until we human guinea pigs let the companies know about it. I was

raised to use both the natural and synthetic for health care. I have an

asthmatic daughter that is too young for the rest of the asthma drugs and is

allergic - severely - to the preservative that they put in the proventil. So I

have turned to the natural to control her asthma. So yes I am well aware of the

dangers of all. But I still stand by my belief that if we do choose to use

natural, then maybe we need to just check the ratios that we are using. We live

in such an imperfect world. There is never an easy answer to anything.

Yoki

I cried unto the Lord with my voice,and he heard me out of his holy hill.

Selah

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Yoki, I must take exception to one thing that you've said...

> I won't have to worry about an 'unknown' side effect that will

never be known until we human guinea pigs let the companies know

about it.

Given how little information has been quanitified on the use

of 'natural' products, and their interactions with each other and

with other 'synthetic' meds, I don't know how you can say that you

won't have to worry about an 'unknown' side effect with a 'natural'

product.

For example - St. 's Wort has been used for years as a mild

antidepressant, right? Hundreds of years of safe use, no problemo,

right? Tell that to the pregnant women who didn't know that SJW

decreases the efficacy of birth control pills. Now THAT's a

depressing side effect!

Excluding the 'synthetics' all together, we still don't have

quantifiable information about interactions between 'naturals'. A

product that has been used 'safely' in China for 300 years may not

react well with a product that has been used 'safely' in South

America for 300 years. Until recent years these products would

virtually never have been used by the same person!

Personally, I think the pharmaceutical firms and the regulatory

agencies do an excellent job of preventing dangerous medications and

interactions from making their way to consumers. People love to

quote the Thalidomide example - but that was what, 30 years ago? I

can only think of a handful of cases that are even remotely similar,

thanks to clinical testing, computer modelling and responsible

prescription. The worst cases have been when a drug or drug

combination was prescribed improperly, like Fen-Phen.

However, in the last five years there have been a large number of

instances where we've learned that natural products can have serious

interactions with other pharmaceuticals...

I'm not knocking the use of natural products - I just think it's

inappropriate to choose them based on a perception of lack of side

effects when the evidence either suggests the opposite, or worse, a

total lack of evidence.

Jules/Vancouver BC (who has just about finished her study break...)

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> Aside from the fact that neem stinks - I will have to take your

word for it - isn't it true that when using a natural preservative

that you may not necessarily use that standard ratios of .2% - 1%.

True, it depends on the product being preserved and the likelihood

that it will become contaminated.

> If we say that for example the ratio for natural preservatives is

around 5%, would not that then begin to offer some protection? when

you get a chance to really look at the info, it says that at 1% it

began to provide the treatment that was necessary in most of the

products it was tested.

I don't quite understand what your first sentence says. I agree that

at 1% the product provided adequate protection in most of the

products tested - although I do think it very alarming that the one

cosmetic product tested did NOT meet criteria - which to me would all

but end this discussion. If it won't preserve cosmetic creams, why

consider it at all?

>So at probably a higher rate, then it would be doing comparable to

the synthetics.

Not necessarily. If a product doesn't have adequate preservative

action at 1%, it does not automatically follow that it would be

adequate at 2%. 2% of a product as a preservative is too high, IMO,

anyway.

>Now the fact that neem stinks, I am sure that they could deodorize

it; much like they do for cocoa butter.

I don't think so. The literature seemed to imply that the

preservative activity was as a result of many of the chemicals that

are considered 'aroma chemicals', like the terpenes. In other words,

take away the neem stink and you take away the active ingredient

> I will defer to your judgement as to the pH of the product. I would

not even began to hazard a guess at that. But let us say that all

other variables were in place, would not upping the percentage of the

natural preservative do the job sufficiently?

Like I said, probably not - the information provided is inadequate.

And again, one of my most serious concerns is that the product is not

standardized. One would have to have a cert for each batch and then

adjust their formulae each time in order to ensure adequate

preservative activity, which could result in totally unreliable

product quality.

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And again, one of my most serious concerns is that the product is not

standardized. One would have to have a cert for each batch and then

adjust their formulae each time in order to ensure adequate

preservative activity, which could result in totally unreliable

product quality.

Thank you very much. Then maybe it would be ok to continue to use a combo of the

two then. That may seem somewhat redundant, but if using a natural preservative,

then using a 'backup' is necessary according to research.

Yoki

I cried unto the Lord with my voice,and he heard me out of his holy hill.

Selah

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> Did not mean to insult the " list " with my obviously sophomoric question.

Yoki, I doubt very much that you insulted anyone on the list, so if I were

you I wouldn't worry about it. I believe that the majority of people on this

list-including myself-would prefer to use natural ingredients if we could

get the same results that we get with what we are currently using. We can't

just jump on the bandwagon to hail in a new product that has no track

record. Watch it, yes, and hope it works, yes. I doubt that there are many

of us on the list that are big enough producers to be able to afford

challenge testing for all our products. Because of this we need to be extra

careful in the choice of preservatives that we use, and only use those that

are tried and true with a track record. For me to use Midicol I would need

to see it used by a major manufacturer for two years without problems.

Pat.

Peace, Joy, Serenity

House of Scents tm. Body Oils, Fragrance Oils, Incense, Candles, Soap, Etc.

pat@...

http://www.houseofscents.com/

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which begs the question - why use the 'natural' and unproved

preservative at all, if you're going to use a backup synthetic

anyway? Is being 99.5% " natural " that much more important than being

99% " natural " ? Especially when being 99.5% natural may still result

in product contamination?

I'm with Pat - I'd want to see it in major use for a minimum of 2

years before trying it myself, plus I'd want to see more substantive

test data.

Jules

> Thank you very much. Then maybe it would be ok to continue to use a

combo of the two then. That may seem somewhat redundant, but if using

a natural preservative, then using a 'backup' is necessary according

to research.

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It is all a matter of choice. I know because I have lived it. Almost lost a

daughter to the wonderful synthetics that the doctors were touting so much. Had

I followed my mind, I would not have had to go through that. I grew up using

herbs and bushes alongside western medicine. I guess it is what you know. You

can only speak from what you have lived. There will be those who will forever

sing the praises of western medicine and there will be those who will sing the

praises of 'alternative' medicine. I walk the line in between, but lean more

towards herbs and bushes.

Now back to soaping and the other good stuff :-)

Yoki

I cried unto the Lord with my voice,and he heard me out of his holy hill.

Selah

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