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Re: Labs from Endo

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That 262 # appears to be an xtra test he did, namely the FREE amt of T3 in

your blood---at least that's what seems logical on this # to me. You have

very high antibodies on that one substance used to create thyroid hormone

(TPO), obviously, but I don't think that he should have ruled out Grave's

Disease yet, at least not this soon, as it seems to me that you should not

have any of the TSI at all. I say this because the fact that you have a " 1 "

instead of a " 0 " could possibly mean something here that may be part of the

" tidal wave " back and forth. I'm hoping that he keeps a close eye on your

thyroid hormones, once he implements the Tapazole, so that you don't go too

low here. Hashi's has a big tendency to do the skitz swings.

Labs from Endo

>I don't know for sure what I need to post but will start with the

> basics done on 3/13:

>

> T3 Total: 305.3 - ref: 80-200 (On 02/21 MD did test showing it was 262

> with a ref of 60-181ng/DL)

> T4 Free: 2.87 - ref: 0.93-1.70

> TSH: 0.005 - ref: 0.27-4.20

> Endo note says okay to start Tapazole 10mg - Ablation would be best

> Thyroperoxidase AB: >1000 - ref: <35 Endo has note on this sheet TSI

> (P) hashimoto

>

> Thyroid Stim lg <1.0 - ref: 0.0-1.3 Endo note says No graves

>

> What else do you need to know?

> Aundrea

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Hi Aundrea,

The TSI test is a stimulation test, not an antibody count. What it

tells us is how much a gland will be stimulated to make T4 & T3 by

stimulating TRab antibodies.

Your test shows that your TSI antibody level is not high enough to

cause hypERthyroidism.

Thyroid Stim lg <1.0 - ref: 0.0-1.3

So your doctor is right --- you have hypERthyroidism from another cause

other than Graves disease.

Did you say you had a sore throat lately? Sometimes a thyroid can be

inflammed due to a virus, causing a large release of thyroid hormone,

and that condition can't be treated with ATDs. Hashimotos rarely comes

with pain.

Since you are very hypERthyroid with almost no stimulating antibodies,

I'm wondering if you have something like Silent thyroiditis (no pain)

or Subacute thyroiditis (with pain) which can also be accompanied by

TPOab and TGab.

See if either of these might fit your situation:

Silent thyroiditis is inflammation of the thyroid gland that involves

alternating hyperthyroidism and hypothyroidism followed by recovery.

Causes: The cause of this type of thyroiditis is unknown. The disease

affects women more often than men and usually develops in people

between age 13 and 80. Also known as: Lymphocytic thyroiditis; Subacute

lymphocytic thyroiditis; Painless thyroiditis

Subacute thyroiditis: involves inflammation of the thyroid gland that

usually follows an upper respiratory infection and then subsides.

The most prominent feature of subacute thyroiditis is gradual or sudden

onset of pain in the region of the thyroid gland. Painful enlargement

of the thyroid gland may persist for weeks or months. The condition is

sometimes associated with fever. Hoarseness or difficulty swallowing

may also develop. Symptoms of thyroid hormone excess (hyperthyroidism)

such as nervousness, rapid heart rate, and heat intolerance may be

present early in the disease. Later, symptoms of too little thyroid

hormone (hypothyroidism) such as fatigue, constipation, or cold

intolerance may occur. Eventually, thyroid gland function returns to

normal.

Symptoms

The initial symptoms are those of hyperthyroidism (overactivity of the

thyroid gland), and may last for 3 months or less. Later symptoms may

be more characteristic of an underactive thyroid (including fatigue,

cold intolerance) until the thyroid recovers.

Symptoms are usually mild, and *may* include:

Fatigue

Frequent bowel movements

Heat intolerance

Increased appetite

Increased sweating

Irritability

Muscle cramps

Menstrual irregularities

Nervousness, restlessness

Palpitations

Weakness

Weight loss

Treatment is based on symptoms. Beta-blockers relieve rapid heart rate

and excessive sweating. (ATDs do not help since the cause is from

excess hormone release, not production)

>

> I don't know for sure what I need to post but will start with the

> basics done on 3/13:

>

> T3 Total: 305.3 - ref: 80-200 (On 02/21 MD did test showing it was

262

> with a ref of 60-181ng/DL)

> T4 Free: 2.87 - ref: 0.93-1.70

> TSH: 0.005 - ref: 0.27-4.20

> Endo note says okay to start Tapazole 10mg - Ablation would be best

> Thyroperoxidase AB: >1000 - ref: <35 Endo has note on this sheet TSI

> (P) hashimoto

>

> Thyroid Stim lg <1.0 - ref: 0.0-1.3 Endo note says No graves

>

> What else do you need to know?

> Aundrea

>

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