Rheumatoid Arthritis May Improve After Helicobacter Pylori Eradication

[Guest guest]

Rheumatoid Arthritis May Improve After Helicobacter Pylori Eradication

08/29/2002

By

Eradication of Helicobacter pylori infection appears to reduce the severity

of rheumatoid arthritis.

This suggests that H pylori infection plays a role in the pathogenesis of

rheumatoid arthritis.

An infectious agent has been previously postulated as a triggering agent for

rheumatoid arthritis, explain investigators from the Università di Genova in

Genoa, Italy. The investigators set out to examine the possible role of H

pylori.

Fifty-eight adult rheumatoid arthritis patients with dyspeptic symptoms were

included in the study. Twenty-eight of these patients were positive for H

pylori infection while the rest were negative.

Infected patients were treated and clinical and laboratory parameters of

rheumatoid arthritis were assessed at baseline and every four months for two

years.

H pylori eradication was successful in all infected patients. These patients

showed significant improvement in all clinical indices of rheumatoid

arthritis while the patients that were originally H pylori-negative showed

little change over the two-year study period.

Also, the patients who underwent H pylori eradication achieved significantly

lower values for erythrocyte sedimentation rate, fibrinogen, a2-globulins

and antinuclear antibody compared with the H pylori-negative patients.

These results suggest a role for H pylori infection in the pathogenesis of

rheumatoid arthritis, and its eradication appears beneficial for infected

rheumatoid arthritis patients, the investigators conclude. They point out,

however, that controlled studies are still needed.

Aliment Pharmacol Ther 2002; 16(7): 1291-1299

[Guest guest]

Sign me up for that! Very interesting article. Thanks, a.

Carol

[ ] Rheumatoid Arthritis May Improve After Helicobacter

Pylori Eradication

Rheumatoid Arthritis May Improve After Helicobacter Pylori Eradication

08/29/2002

By

Eradication of Helicobacter pylori infection appears to reduce the severity

of rheumatoid arthritis.

This suggests that H pylori infection plays a role in the pathogenesis of

rheumatoid arthritis.

An infectious agent has been previously postulated as a triggering agent for

rheumatoid arthritis, explain investigators from the Università di Genova in

Genoa, Italy. The investigators set out to examine the possible role of H

pylori.

Fifty-eight adult rheumatoid arthritis patients with dyspeptic symptoms were

included in the study. Twenty-eight of these patients were positive for H

pylori infection while the rest were negative.

Infected patients were treated and clinical and laboratory parameters of

rheumatoid arthritis were assessed at baseline and every four months for two

years.

H pylori eradication was successful in all infected patients. These patients

showed significant improvement in all clinical indices of rheumatoid

arthritis while the patients that were originally H pylori-negative showed

little change over the two-year study period.

Also, the patients who underwent H pylori eradication achieved significantly

lower values for erythrocyte sedimentation rate, fibrinogen, a2-globulins

and antinuclear antibody compared with the H pylori-negative patients.

These results suggest a role for H pylori infection in the pathogenesis of

rheumatoid arthritis, and its eradication appears beneficial for infected

rheumatoid arthritis patients, the investigators conclude. They point out,

however, that controlled studies are still needed.

Aliment Pharmacol Ther 2002; 16(7): 1291-1299

[Guest guest]

Maybe this explains why the antibiotic protocol works on some people and

does nothing for others.

a

> Sign me up for that! Very interesting article. Thanks, a.

>

> Carol

>

>

> [ ] Rheumatoid Arthritis May Improve After Helicobacter

> Pylori Eradication

>

> Rheumatoid Arthritis May Improve After Helicobacter Pylori Eradication

>

> 08/29/2002

> By

>

>

> Eradication of Helicobacter pylori infection appears to reduce the severity

> of rheumatoid arthritis.

>

> This suggests that H pylori infection plays a role in the pathogenesis of

> rheumatoid arthritis.

>

> An infectious agent has been previously postulated as a triggering agent for

> rheumatoid arthritis, explain investigators from the Università di Genova in

> Genoa, Italy. The investigators set out to examine the possible role of H

> pylori.

>

> Fifty-eight adult rheumatoid arthritis patients with dyspeptic symptoms were

> included in the study. Twenty-eight of these patients were positive for H

> pylori infection while the rest were negative.

>

> Infected patients were treated and clinical and laboratory parameters of

> rheumatoid arthritis were assessed at baseline and every four months for two

> years.

>

> H pylori eradication was successful in all infected patients. These patients

> showed significant improvement in all clinical indices of rheumatoid

> arthritis while the patients that were originally H pylori-negative showed

> little change over the two-year study period.

>

> Also, the patients who underwent H pylori eradication achieved significantly

> lower values for erythrocyte sedimentation rate, fibrinogen, a2-globulins

> and antinuclear antibody compared with the H pylori-negative patients.

>

> These results suggest a role for H pylori infection in the pathogenesis of

> rheumatoid arthritis, and its eradication appears beneficial for infected

> rheumatoid arthritis patients, the investigators conclude. They point out,

> however, that controlled studies are still needed.

> Aliment Pharmacol Ther 2002; 16(7): 1291-1299

>

>

>

>

>