Re: Milnacipran

[Guest guest]

I've never heard of this drug before. Interesting. Has anyone tried

it?

dee

>

> Milnacipran relieves chronic pain and depression

> Milnacipran is the first in a new class of antidepressants known as

> Norepinephrine Serotonin Reuptake Inhibitors (or NSRI's). It has

> equal potency for inhibiting the reuptake of both serotonin and

> noradrenaline. Extensive studies provide clear-cut evidence of its

> efficacy in both severe and moderate depression in hospitalized and

> community settings.

>

> What makes Milnacipran different from the Selective Serotonin

> Reuptake Inhibitors (SSRIs) – drugs like Prozac® – and Selective

> Norepinephrine Reuptake Inhibitors (SNRIs) – drugs like Effexor –

is

> that Milnacipran affects two neurotransmitters, norepinephrine and

> serotonin, almost equally (a 3:1 norepinephrine to serotonin

> balance). In contrast a SNRI, tends to act much more on serotonin

> than norepinephrine, (Effexor has a 1:30 norepinephrine to

serotonin

> ratio).

>

[Guest guest]

Has anyone here tried this??? I am on Lyrica and after a year, I really

dont see any improvement at all and want to come off it to try

something else. I am on meds for depression, so if I try this med,

would my doc take me off my depression meds? I take lythium right now,

so I dont know if there would be a problem - Im sure my doc could find

that out though. I would love to try this drug, I am curious if anyone

here has any personal experiance with it. Or doeas anyone have

something else that they are taking that is working well?? Would this

med make my pain meds work better?

Blessings

Dr.

[Guest guest]

I was the same way, until we backed off the lyrica. then within a 10 day period

i was back to the before lyrica days.

so i got a little hint of ,it wasn't doing the best i thought it should have.

but backing off of it was worse. for me anyway

Diane    

[Guest guest]

, did you notice any difference in your mood while you were on

it? Also, can i ask where you imported it from? I'm in Australia.

Cheers,

D

> I imported Milnacipran (also called Ixel) maybe a year or so ago. I

> don't recall now how much I started with, from what I had read the

> proper dose can be extremely variable depending on what you're using

> it for. (Whether for fibro pain or for depression). Anyway, it

> worked wonders as far as knocking out my inflammation pain. But I

> did have early morning nausea, which is one of the common side-

> effects. The nausea is supposed to subside after awhile, and it may

> have, I didn't stick with it long enough to find out. It seemed to

> have a great " hangover " effect, my pain didn't return for a long

> time.

[Guest guest]

Hi-

I imported it from International Aging Systems,,,,,they're located in

the Channel Islands,,,,,I don't know if they can ship to Australia,

for some odd they can't ship to the UK or EU,,,,,,,

but you could check with them, they're really nice people, I've dealt

with them for years.

I didn't notice a change in mood, Not at the dose I was on, But

depression isn't a problem for me. Rarely, anyway, So, I really

can't say in that respect,

Cheeseville, WI

, did you notice any difference in your mood while you were on

it? Also, can i ask where you imported it from? I'm in Australia.

Cheers,

D