regulation of cardiac rhythm in patients with rheumatoid arthritis and multiple sclerosis

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Study nervous regulation of cardiac rhythm in patients with rheumatoid

arthritis and multiple sclerosis

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=1\

2469632 & dopt=Abstract

Ter Arkh 2002;74(10):48-52

AIM: To study nervous regulation of cardiac rhythm (CR) in patients with

rheumatoid arthritis (RA) and multiple sclerosis (MS).

MATERIAL AND METHODS:

Nervous regulation of cardiac rhythm was studied in 57 patients with RA

and MS vs 40 healthy subjects.

RESULTS:

It was found that nervous regulation of CR in RA and MS patients at rest

is characterized by imbalance of functions of the autonomic nervous

system with enhancement of ergotropic effects in patients with RA and

deficiency of trophotropic impacts in growing ergotropic component in

patients with MS.

Stress tests led to dysfunction of CR central regulation with disturbed

activity of the

subcortical nervous centers (SNC) and autonomic maintenance of the

processes, were

characterized in emotional stress by insufficient activity of SNC and

enhancement of

parasympathetic effects in RA patients, hyperactivation of SNC with

intensification of

sympathetic impacts in MS patients manifesting in destabilizing effect

of the sympathetic

nervous system in both groups of patients.

CONCLUSION:

The findings should be taken into consideration when vegetotropic drugs

are used in the

treatment of RA and MS patients.