Guest guest Posted July 24, 2008 Report Share Posted July 24, 2008 Hi , I'll try to decipher this report for you. If it was me I would heavily consider surgery. <<<Direct smear rt thyroid: adenoatous hyperplasia w/cystic degerneration and rare nuclear grooves. CELL BLock: Pigmented histocytes and banal follicular epithelium present, favor degenerative cyst/nodule. >>> This says to me that there is over abundance of tissue that is falling apart and the nucleus of these cells has abnormal rare grooves in them. <<<Direct smear comment: Because of the rare nuclear grooves and anisonucleosis present in direct smear findings, the possibility of papillary carcinoma cannot be entirely excluded.>>> Anisonucleosis means wide variation in cell size. Cancer cannot be excluded because there are abnormal cells with grooves and size varation. <<<Direct smear lft thyroid: Consistent w/adenomatous hyperplasia with rare Hurthle cells. CELL BLOCK: Hypocellular - non diagnostic. >>> Hurthle cells - enlarged epithelial cells often seen in Hashimoto's and/or thyroid cancer. They can't tell which. <<<Comment: The presence of rare Hurthle cells in direct smear may indicate Hurthle cell metaplasis, though the differential diagnosis also includes Hashimoto's thyroiditis.>>> Metaplasia - Cells that change in appearance from normal to abnormal for that particular tissue or organ. It could be Hashi's or it could be cancer. From EndocrineWeb.com http://www.endocrineweb.com/fna.html Follicular carcinoma and Hurthle cell carcinoma cannot be diagnosed by FNA biopsy. This is an important point. Since benign follicular adenomas cannot be differentiated from follicular cancer (~12% of all thyroid cancers) these patients often end up needing a formal surgical biopsy, which usually entails removal of the thyroid lobe which harbors the nodule. HTH, Bj > > I'm scheduled for a surgical consultation 08/12 and wondered if anyone > could explain any of the cytology report. The nurse would only say they > found atypical cells. Dr told me before the results came back he was > concerned about the looks of the nodules from U/S and did biopsy that > day in his office, and asked me if I understood why and I told him I > think you feel it could be cancer, he said yes. Here's the report > Direct smear rt thyroid: adenoatous hyperplasia w/cystic degerneration > and rare nuclear grooves. CELL BLock: Pigmented histocytes and banal > folicular epithelium present, favor degenerative cyst/nodule. Direct > smear comment: Because of the rare nuclear grooves and anisonucleosis > present in diret smear findings, the possibility of papillary carcinoma > cannot be entirely excluded. > Direct smear lft thyroid: Consistent w/adenomatous hyperplasia with > rare Hurthle cells. CELL BLOCK: Hypocellular - non diagnostic. > Comment: The presence of rare Hurthle cells in direct smear may > indicate Hurthle cell metaplasis, though the differential diagnosis > also includes Hashimoto's thyroiditis. > I'm trying to get my consultation moved up as soon as possible as I > want this taken out. Would this mean a partial or total > thyroidectomy? Anyone had anything similar. I take no meds btw. > I'd appreciate any input. > Thank you > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 26, 2008 Report Share Posted July 26, 2008 Thank you so much it was very helpful! > > > > I'm scheduled for a surgical consultation 08/12 and wondered if > anyone > > could explain any of the cytology report. The nurse would only say > they > > found atypical cells. Dr told me before the results came back he > was > > concerned about the looks of the nodules from U/S and did biopsy > that > > day in his office, and asked me if I understood why and I told him > I > > think you feel it could be cancer, he said yes. Here's the report > > Direct smear rt thyroid: adenoatous hyperplasia w/cystic > degerneration > > and rare nuclear grooves. CELL BLock: Pigmented histocytes and > banal > > folicular epithelium present, favor degenerative cyst/nodule. > Direct > > smear comment: Because of the rare nuclear grooves and > anisonucleosis > > present in diret smear findings, the possibility of papillary > carcinoma > > cannot be entirely excluded. > > Direct smear lft thyroid: Consistent w/adenomatous hyperplasia with > > rare Hurthle cells. CELL BLOCK: Hypocellular - non diagnostic. > > Comment: The presence of rare Hurthle cells in direct smear may > > indicate Hurthle cell metaplasis, though the differential diagnosis > > also includes Hashimoto's thyroiditis. > > I'm trying to get my consultation moved up as soon as possible as I > > want this taken out. Would this mean a partial or total > > thyroidectomy? Anyone had anything similar. I take no meds btw. > > I'd appreciate any input. > > Thank you > > > > > Quote Link to comment Share on other sites More sharing options...
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