Guest guest Posted January 23, 2008 Report Share Posted January 23, 2008 I'm confused, The " USAMRIID's MEDICAL MANAGEMENT OF BIOLOGICAL CASUALTIES HANDBOOK Fifth Edition published in August 2004 by the U.S. ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES FORT DETRICK FREDERICK, MARYLAND has this to say about heat disinfection of trichothecene mycotoxins, such as those in stachybotrys chartarum or " household mold " as Mr Havics puts it, reminiscent of " household pets " or the like.. " TOXIN CHARACTERISTICS The trichothecene mycotoxins are low-molecular-mass (250-500 daltons) nonvolatile compounds produced by filamentous fungi (molds) of the genera Fusarium, Myrotecium, Trichoderma, Stachybotrys and others. The structures of approximately 150 trichothecene derivatives have been described in the literature. These substances are relatively insoluble in water but are highly soluble in ethanol, methanol and propylene glycol. The trichothecenes are extremely stable to heat 97 and ultraviolet light inactivation. They retain their bioactivity even when autoclaved; heating to 1500o F for 30 minutes is required for inactivation. Hypochlorite solution alone does not effectively inactivate the toxins. Rather, adding 0.1M NAOH to a 1% hypochlorite solution, with 1 hour contact time is required. Soap and water effectively remove this oily toxin from exposed skin or other surfaces. MECHANISM OF TOXICITY The mycotoxins appear to have multiple mechanisms of action, many of which are poorly understood. Their most notable effect stems from their ability to rapidly inhibit protein and nucleic acid synthesis. Thus, they are markedly cytotoxic to rapidly dividing cells such as in the bone marrow, GI tract (mucosal epithelium), skin, and germ cells. Because this cytotoxic effect imitates the hematopoietic and lymphoid effects of radiation sickness, the mycotoxins are referred to as " radiomimetic agents. " The mycotoxins also alter cell membrane structure and function, inhibit mitochondrial respiration, and inactivate certain enzymes. " ..... There you have it.. Anyway, the point I guess that I am trying to make is that they are extremely durable substances according to the Army, who should know, and their dangers should NOT be trivialized. Lots of people are sick and the fact that other people who should know better are ignoring that and them and then trying to confuse the situation is really evil. Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.