PDF Article about MELD Liver Allocation

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This article discusses:

" The current paradigm; donor livers are allocated on the basis of

medical urgency. Thus, the onus(necessity)is on the transplant

community to refine the allocation system continuously so that livers

are targeted to patients who need them most. The current model for

end-stage liver disease (MELD)-based allocation system works well,

accurately predicting short-term mortality for the majority (83 to

87%) of waitlisted candidates. However, there are patients with liver

diseases whose survival is dependent upon factors other than the

severity of the liver disease and who may not manifest derangements in

their MELD parameters. Such patients may be underserved by current

MELD policies. This article reviews the development of MELD and the

MELD-based liver allocation system and addresses issues relevant to

whether this system may be improved. "

http://gidiv.ucsf.edu/LTsyllabus/Biggins.pdf

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MaC