Was: Controlled Drugs Dumped Unconrolled - now Pharm disposal risk

[Guest guest]

1.    Pharmaceuticals in wastewater and other water is not a new issue,

here or South America or Europe, but newly

being updated:

ML, Bowron JM. The fate of pharmaceutical chemicals

in the aquatic environment. J Pharm Pharmacol 1985;37(1):1–12.

Ternes T. Occurrence of drugs in German sewage treatment plants

and rivers. Water Res 1998;32:3245–60.

Seiler R, Zaugg S, J, Howcroft D. Caffeine and

pharmaceuticals as indicators of waste water contamination

in wells. Ground Water 1999;37:405–10.

Buser H-R, Poiger T, Muller M. Occurrence and

environmental

behavior of the chiral pharmaceutical drug ibuprofen in

surface waters and in wastewater. ES & T 1999;33:2529–35

Stumpf M, Ternes T, Wilken R, Rodrigues S, Baumann W. Polar

drug residues in sewage and natural waters in the state of Rio

de Janeiro, Brazil. Sci Total Environ 1999;225:135–41.

Kolpin D, Furlong E, Meyer M, Thurman E, Zaugg S, Barber L,

Buxton H. Pharmaceuticals, hormones, and other wastewater

contaminants in U.S.

streams, 1999–2000 — a national

reconnaissance. ES & T 2002;36:1202–11.

McArdell C, Molnar E, Suter M, Giger W. Occurrence and fate of

macrolide antibiotics in wastewater treatment plants and in

the Glatt Valley Watershed,

Switzerland.

ES & T

2003;37:5479–86.

Stackelberg P, Furlong E, Meyer M, Zaugg S, A,

Reissman D. Persistence of pharmaceutical compounds and

other organic wastewater contaminants in a conventional

drinking-water treatment plant. Sci Total Environ

2004;329:99–113

Palmer, Sources of pharmaceutical pollution in the New York

City Watershed, Sci Total Envon, 394, 90-102, 2008

2.    It has been suggested to not be a significant risk to humans:

Schwabb, Human pharmaceuticals in US surface waters, Reg Toxicol

Pharmacol, 42, 3, 296-312, 2005

(prepared by a lot of pharma folks* - some of whom I know personally

and have challenged a few things they state)

3.    However, there are clearly some potential ecological risks:

Matamoros,

Behaviour of pharmaceutical products and biodegradation in subsurface flow, Sci

Total Environ, 394, 171-176, 2008

Kostich, Risks to aquatic organisms posed by human pharmaceutical use,

Sci Total Environ, 389, 329-339, 2008 

[EPA folks]

Tony

*Bradley W. Schwab a, Eileen P. b, Janice M. Fiori c, J.

Mastrocco d,

M. Roden e, Cragin f, D. MeyerhoV c, J.

D’Aco g,¤,

D. a

a AMEC Earth and Environmental, 239 Littleton Road, Suite 1B, Westford,

MA 01886,

USA

b Bristol-Myers Squibb Company, P.O. Box 191, New Brunswick, NJ 08903,

USA

c Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN 46285, USA

d PWzer, 235 East 42nd

Street, New York, NY 10017, USA

e Schering-Plough, 1095 Avenue, Union, NJ 07083, USA

f Merck and Co., Two Merck Drive, Whitehouse

Station, NJ 08889,

USA

g Quantum Management Group, 1187 Main Avenue, Clifton, NJ 07011, USA

.......................................................................

" Tony " Havics, CHMM, CIH, PE

pH2, LLC

5250 E US 36, Suite 830

Avon, IN

46123

www.ph2llc.com

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90% of Risk Management is knowing where to place the decimal point...any

consultant can give you the other 10%(SM)

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