Guest guest Posted December 11, 2008 Report Share Posted December 11, 2008 I believe that some people develop a chemical hypersensitivity that involves the sensing of a specific chemical via a mechanism similar to an antigen-antibody complex but is, instead, a chemical-ligand complex sensed by neurons on the vanilloid receptor of the trigeminal nerve. http://www.sigmaaldrich.com/sigma/rbi-handbook/sg_ls_cs_rbibook_vanilloid.pdf Steve Temes Muller said that the way we perceive a stimulus depends on the nerve or sensory system that conveys it rather than the physical nature of the stimulus itself. In the case of irritating odors, we perceive them as irritating because they are transmitted via the trigeminal nerve, leading the brain to interpret the message as pain rather than as a smell. The researchers say their findings raise new questions about how irritating odors are detected. They say more research is needed to explore whether solitary chemosensory cells are programmed to recognize specific irritants, which receptors are involved, and what steps a solitary chemosensory cell uses to convert a chemical stimulus to a signal it relays to the trigeminal nerve. Quote Link to comment Share on other sites More sharing options...
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