Fwd: Re: [Salt-n-C] Asthma and salt

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This is an interesting article citing studies supporting salt's effectiveness in treating asthma. Apparently, exercise induced asthma is connected to dehydration of the lungs. This is something my youngest daughter deals with. I forwarded this to her and suggested she start using her salt pipe frequently. sorry for the poor text quality. I'm forwarding it from another group. pennyCarol wickstrom <surbilly@...> wrote: Salt-n-C From: Carol wickstrom <surbilly@...>Date: Fri, 2 Mar 2007 18:28:33 -0800 (PST)Subject: Re: [salt-n-C] Asthma and salt A young girl on LS was cured of her asthma with s/c.:)No more steriods...totally healed. --- jill1313 <jenbooks13hotmail> wrote:> This activity has expired.> CME in this activity indicates that it was developed> according to> ACCME guidelines and was certified for credit by an> accredited CME> provider. Medscape cannot attest to the timeliness> of expired CME> activities.> > June 17, 2005 — Increased dietary salt decreases> lung function and> diffusion capacity after exercise, according to the> results of a> randomized, double-blind trial published in the June> issue of Medicine> and Science

in Sports and Exercise.> > "Recent studies have supported a role for dietary> salt as a modifier> of the severity of exercise-induced asthma (EIA),"> write D.> Mickleborough, PhD, from Indiana University in> Bloomington, and> colleagues. "It has been suggested that transient> dehydration of the> airways activates inflammatory mediators such as> histamine,> neuropeptides, and the arachidonic acid metabolites,> leukotrienes> (LTs), and prostanoids from airway cells, resulting> in bronchial> smooth muscle contraction. Alternatively, it has> been suggested that> rapid rewarming of the airways following exercise> leads to reactive> hyperemia resulting in vascular engorgement and> perivascular edema,> which would further contribute to airway narrowing> caused by> bronchoconstriction."> >

In this crossover study, 24 patients entered the> study with their> normal salt diet (NSD) and were then given either a> low-salt diet> (LSD) or a high-salt diet (HSD) for two weeks, with> a one-week washout> period between diets. Pre- and postexercise> spirometry, pulmonary> diffusion capacity (DLCO) and its subdivisions, and> induced sputum> were obtained during the NSD and at the end of each> dietary period.> > Mean forced expiratory volume in 1 second (FEV1)> decreased by 7.9% ±> 2.8% with the LSD, 18.3% ± 4.0% with the NSD, and by> 27.4% ± 3.2% with> the HSD at 20 minutes after exercise. With the NSD> and HSD, DLCO and> its subdivisions decreased significantly (P < .05).> Compared with> baseline values, postexercise pulmonary capillary> blood volume> increased by 6.3 mL with the NSD and by 9.6 mL

with> the HSD (P < .05> for both comparisons), with no significant change> with the LSD.> > Compared with the LSD, the NSD and HSD were> associated with increased> exercise-induced sputum neutrophil and eosinophil> differential cell> counts and induced sputum supernatant concentration> of eosinophil> cationic protein, interleukin (IL)-1?, IL-8,> LTC4 through LTE4, LTB4,> and prostaglandin D2 (P < .05 for all comparisons).> > "Our findings indicate that dietary salt loading> enhances airway> inflammation following exercise in asthmatic> subjects, and that small> salt-dependent changes in vascular volume and> microvascular pressure> might have substantial effects on airway function> following exercise> in the face of mediator-induced increased vascular> permeability," the> authors

write.> > Med Sci Sports Exerc. 2005;37:904-917> > __________________________________________________________Need Mail bonding?Go to the Q & A for great tips from Answers users.http://answers./dir/?link=list & sid=396546091