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whey protein reduces blood pressure and inhibits ACE

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Whey protein reduces blood pressure and inhibits ACE so maybe it's

working like Benicar. Ha, ha, ha. Wouldn't that be a trip. How's this

for a couple of research summaries. All I can say is we are all

trying to figure out what the heck the elephant is in the dark. Maybe

we should call cfs " blind elephant disease. " a Carnes

http://www.vitaminlife.com/view_article-exec/article_id/805

Hydrolyzed whey proteins are said to reduce blood pressure according

to an article written by the Whey Protein Institute. This provides an

option for people with hypertension without the side effects that

drugs produce. A study was conducted at the University of Minnesota

in June 2004 where people with mild hypertension were asked to take

whey protein supplements for six weeks and make no other changes in

their exercise and eating habits. According to the study, " Treatment

resulted in a significant reduction in blood pressure levels by the

end of the first week of treatment. This effect was maintained

throughout the study. "

http://www.lef.org/magazine/mag2002/jan2002_abs_03.html

Eur J Clin Invest 2001 Feb;31(2):171-8

Lactokinins: whey protein-derived ACE inhibitory peptides.

Angiotensin-I-converting enzyme (ACE) has been classically associated

with the renin-angiotensin system which regulates peripheral blood

pressure. Peptides derived from the major whey proteins, i.e. alpha-

lactalbumin (alpha-la) and beta-lactoglobulin (beta-lg) in addition

to bovine serum albumin (BSA), inhibit ACE. Some of these inhibitory

peptides, i.e. alpha-lactorphin (alpha-la f(50-53)), beta-lactorphin

(beta-lg f(102-105)), beta-lactotensin (beta-lg f(146-149) and

albutensin A (BSA f(208-216)), have other bioactivities. The most

potent lactokinin reported to date, (beta-lg f(142-148)), has an ACE

IC50 of 42.6 mumol/l. While they do not have the inhibitory potency

of synthetic drugs commonly used in the treatment of hypertension,

these naturally occurring peptides may represent

nutraceutical/functional food ingredients for the

prevention/treatment of high blood pressure. Studies with gastric and

pancreatic proteinase digests of whey proteins indicate that enzyme

specificity rather than extent of hydrolysis dictates the ACE

inhibitory potency of whey hydrolysates.

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