Re: Chronic Fatigue/Gilberts Symdrome

[Guest guest]

Barb,

My husband has chronically elevated uncongugated bilirubin (about double top end of normal), we think he has Gilbert's Syndrome, but we haven't really looked into it properly (he also has Factor V Leiden which is a genetic coagulation mutation-I'm glad we did have kids ). Thanks for posting about this, it is prompting me to look into it again.

Is your brother ill or has he got symptoms?

Let me know if you find out things re drug metabolising mechanisms and Gilbert's Syndrome. I have been trying to get Jacques to stick to a low fat-low carb-low sugar diet with limited success! He loves eating and cooking.

Nelly

[infections] Chronic Fatigue/Gilberts Symdrome

http://www.gilbertssyndrome.com/ It was recently discovered (thru screening for something else) that my brother (age 55) has this hereditary condition. Apparently this genetic anomoly in the liver has only been known about 10 years... I'm not on the CFS list any more- sp maybe someone will cross post this- I don't ever remember Gilberts syndrome being discussed on that list - but reference is made in these articles about it. I'll have to research it further- since I have had on occassion mildly elevated bilirubin without elevated liver enzymes in association with some drug metabolism ( case # 1: my relationship damaging arguement with T. Marshall about whether I could metabolize Zith or not- specifically whether my reaction (and elevated bilirubin while on it) was a drug reaction or a herx.) This info adds more data in favor of drug metabolic reaction.Barb