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melarsoprol doses in West African trypanosomiasis

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in Health, Medicine and Natural Healing 07

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Wow, these doses are large in terms of As mass. The Angola protocol

described here delivers 30.2 mg As /day, twelve times (spread out over

a few weeks). That's 360 mg total.

[free text] http://www.smw.ch/dfe/set_archiv.asp?target=2002/05/smw-

09902

It's very interesting that certain drugs are effective against West

African trypanosomiasis only in its early stages. Why is that? Is there

maybe a physiological resistance that sets in once the bugs get bottled

up and (perhaps) slow their metabolism?

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