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IgM and ANA

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> Can anyone tell me the significance of being told that I seem to have a

> consistently elevated IgM (plus up-reg ANA)?

>

> Rosie

>

Well, ANA are anti-nuclear antibodies. This is used as one indication

of lupus, but it's not very specific. A fair number of healthy nromals

have high ANA, as do various sorts of sick people. So, it might be a

coincidence. I don't know about it in great detail, though... your

doctor probably knows a lot more than me. But, you can also read about

it on medical sites... I'd suggest looking for ones authored by

someone with a degree, like this one on ANA:

http://www.medicinenet.com/antinuclear_antibody/article.htm

....rather than some random site that no one is taking any

accountability for.

As for high IgM... I don't know anything about it really... but you

probably want to do a search using the term " hyperimmunoglobulinemia M. "

Bear in mind, there may be various different disease descriptions,

like " essential hyperIgM, " " hyperIgM with yada yada, " etc, which may

be very different in cause and nature.

As you may know... most of us here have various sorts of immune

diseases with fatigue, pain, etc... and happen to be responders to

antibacterial treatment, for reasons that are basically unclear.

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