Re: 342-132.pdf (application/pdf Object)

[Guest guest]

I've always been leery of flouride but strangely have never had to deal with it since every place I've lived has been strongly opposed to flouridation. Do you drink flouridated water now? If so, can you switch to bottled and see if you feel better? penny Windsor <rwindsor@...> wrote: Dear All I might be going ratty in my old age but I always felt better when I didn't drink fluoridated water. Maybe there is something

in it. Any comment , Rich? Rhttp://www.fluoride-journal.com/01-34-2/342-132.pdf

[Guest guest]

Hi, .

Sorry about my slow response to your post. I haven't been here

lately. (Too much action to follow on the methylation block

treatment. Over 50 people on it now, with glowing reports coming in

almost daily. If you want to check it out, join the ImmuneSupport CFS

discussion board.)

Thanks for posting this paper. I think it's very interesting. I don't

understand the biochemistry of fluoride detox for sure. However,

fluoride is most assuredly a toxin, and inorganic chemistry would

suggest that it would bind tightly to calcium or magnesium in the body

to form very insoluble minerals. I don't understand exactly how this

would end up using glutathione, but here's a possibility: I think the

phagocytes (neutrophils and perhaps also macrophages) would engulf

these mineral particles and attempt to break them down, which they

would not be able to do. However, the attempt would produce a

respiratory burst, with lots of reactive oxygen species produced.

Glutathione would be used in quenching these oxidizing species to

protect the body from them.

This is a similar mechanism to what occurs in at least some cases of

pulmonary fibrosis, in my opinion. The person inhales silicates or

some other material that can't be broken down in the body, and the

phagocytes try to break them down, but are not able to do so with the

chemical armamentarium they have. The resulting oxidative stress

damages the lungs, and ultimately the fibroblasts wall off the

particles, unfortunately in the interstitial space between the air sacs

and the capillaries, which cuts down the oxygen diffusion rate. My

mother-in-law died from that a couple of months ago.

Rich

>

> Dear All

> I might be going ratty in my old age but I always felt better when I

didn't drink fluoridated water. Maybe there is something in it. Any

comment , Rich?

> R

> http://www.fluoride-journal.com/01-34-2/342-132.pdf

>

[Guest guest]

Dear Rich

Thanks for the reply. This is something I may follow in greater detail (If I can get organised) :-)

I started on Betaine HCl, only thing available locally and feel much better, I'll see my duc shortly and redo my folate and B12 levels (previously 10 X over range). It might be instructive.

Regards

R

[infections] Re: 342-132.pdf (application/pdf Object)

Hi, .Sorry about my slow response to your post. I haven't been here lately. (Too much action to follow on the methylation block treatment. Over 50 people on it now, with glowing reports coming in almost daily. If you want to check it out, join the ImmuneSupport CFS discussion board.) Thanks for posting this paper. I think it's very interesting. I don't understand the biochemistry of fluoride detox for sure. However, fluoride is most assuredly a toxin, and inorganic chemistry would suggest that it would bind tightly to calcium or magnesium in the body to form very insoluble minerals. I don't understand exactly how this would end up using glutathione, but here's a possibility: I think the phagocytes (neutrophils and perhaps also macrophages) would engulf these mineral particles and attempt to break them down, which they would not be able to do. However, the attempt would produce a respiratory burst, with lots of reactive oxygen species produced. Glutathione would be used in quenching these oxidizing species to protect the body from them.This is a similar mechanism to what occurs in at least some cases of pulmonary fibrosis, in my opinion. The person inhales silicates or some other material that can't be broken down in the body, and the phagocytes try to break them down, but are not able to do so with the chemical armamentarium they have. The resulting oxidative stress damages the lungs, and ultimately the fibroblasts wall off the particles, unfortunately in the interstitial space between the air sacs and the capillaries, which cuts down the oxygen diffusion rate. My mother-in-law died from that a couple of months ago.Rich >> Dear All> I might be going ratty in my old age but I always felt better when I didn't drink fluoridated water. Maybe there is something in it. Any comment , Rich?> R> http://www.fluoride-journal.com/01-34-2/342-132.pdf>