Re: Question on Transfer Factor (Rich.. or anyone else)

[Guest guest]

OK Here's the reply I sent him....

Yah- hey have a website called 4Life Transfer factor..

Hmmmmmmmm I dunno.

Mac:

Look at the dosages of the products used to enhance the immune system

in the abstract below. Part of the reason I've never really

purchased a TF product is that it just seems such a complicated mix

of stuff.... Isn't Transfer Factor just a term anyway? Most of the

people I know who use what they call " TF " get the protein from Whey .

What exactly is your product? The website mentions Amino acids from

eggs and colostrum? Or is it more?

Thanks,

Barb Peck

Immunol Invest. 2002 May;31(2):137-53. Links

Increased tumor necrosis factor alpha (TNF-alpha) and natural killer

cell (NK) function using an integrative approach in late stage

cancers.

See D, Mason S, Roshan R.

Center for Advanced Medicine, Encinitias, California 92024, USA.

darrylsee@...

Natural products may increase cytotoxic activity of Natural Killer

Cells (NK) Tumor Necrosis Factor alpha (TNF-alpha) while decreasing

DNA damage in patients with late-stage cancer. Pilot studies have

suggested that a combination of Nutraceuticals can raise NK cell

function and TNF-alpha alpha activity and result in improved clinical

outcomes in patients with late stage cancer. The objective of the

study is to determine if Nutraceuticals can significantly raise NK

function and TNF levels in patients with late stage cancer. After

informed consent was obtained, 20 patients with stage IV, end-stage

cancer were evaluated (one bladder, five breast, two prostate, one

neuroblastoma, two non-small cell lung, three colon, 1 mesothelioma,

two lymphoma, one ovarian, one gastric, one osteosarcoma).

Transfer Factor Plus (TFP+, 3 tablets 3 times per day), IMUPlus (non

denatured milk whey protein, 40 gm/day); Intravenous (50 to 100

gm/day) and oral (1-2 gm/day) ascorbic acid; Agaricus Blazeii Murill

teas (10 gm/day); Immune Modulator Mix (a combination of vitamin,

minerals, antioxidants and immune-enhancing natural products);

nitrogenated soy extract (high levels of genistein and dadzein) and

Andrographis Paniculata (500 mg twice, daily) were used. Baseline NK

function by standard 4 h 51Cr release assay and TNF alpha and

receptor levels were measured by ELISA from resting and

phytohemagglutinin (PHA) stimulated adherent and non-adherent

Peripheral Blood Mononuclear Cell (PBMC). Total mercaptans and

glutathione in plasma were taken and compared to levels measured 6

months later.

Complete blood counts and chemistry panels were routinely monitored.

As of a mean of 6 months, 16/20 patients were still alive. The 16

survivors had significantly higher NK function than baseline (p < .01

for each) and TNF-alpha levels in all four cell populations studied

(p < .01 for each). Total mercaptans (p < .01) and TNF-alpha receptor

levels were significantly reduced (p < .01). It was also observed

that hemoglobin, hematocrit and glutathione levels were significantly

elevated. The only toxicity noted was occasional diarrhea and nausea.

The quality of life improved for all survivors by SF-36 form

evaluation.

An aggressive combination of immunoactive Nutraceuticals was

effective in significantly increasing NK function, other immune

parameters and hemoglobin from PBMC or plasma in patients with late

stage cancers. Nutraceutical combinations may be effective in late

stage cancers. Clinical outcomes evaluations are ongoing.

PMID: 12148949 [PubMed - indexed for MEDLINE]

>

> Anyone ever heard of Dr. Mac Barksdale?

>

> He's emailing me quite a bit of info on TF (for horses with

chronic

> Lyme- they can't take alot of abx)... but I can't get him to tell

me

> what exactly his product comes from (colostrum??)or what the

product

> is.. Cpmpany is called 4Life and toutes boosting the immune

system's

> Natural killer cells by 400%........ anybody hear of this guy? or

This

> company or product?

>

> Here's a quote:

> " Transfer Factor " is an array of Cytokines and Cytokine products.

> Cytokines are protein molecules produced by cells of the immune

system

> (such as T-cells and B-cells) for the communication of immune

signals.

> Cytokines are mostly secreted in a soluble form, though some

cytokines

> are known to exist attached on cell surface. Soluble cytokines

secreted

> from one cell will bind specifically to their respective receptor

> molecules on the cell surfaces of the target

> cells. END QUOTE...

>

> So what could be taken orally that would fit this bill????

> I'm trying to decide if he's legit?

>

> Barb

>