Re: Bugs vs. Immunity -- Tony

[Guest guest]

Been saving up $ to see this doc -- a naturopath who specializes in CFS -- for

more than

a year. She uses a variety of labs that specialize in different areas.

She ordered a CSDA (stool test) from Meridian Valley -- they actually grow the

bugs rather

than just looking for antigens. Found no parasites this time, but the

" non-candida yeast "

and higher levels of pseudomonas.

I had never heard of pseudomonas before, so was surprised as well. Pseudos can

be a

player in someone with CFS:

http://www.ncbi.nlm.nih.gov/sites/entrez?

db=pubmed & list_uids=17007934 & cmd=Retrieve & indexed=google

Thanks Tony -- and thanks for not screaming!

Dan

> > > > > >

> > > > > > Hi, all.

> > > > > >

> > > > > > I know that some folks here would prefer that I not post

> things

> > > > > about

> > > > > > the methylation cycle block treatment on this list, but

> please

> > > > > > forgive me for this one. I think it's a biggie, and I think

> > > > > > everybody here should hear about it.

> > > > > >

> > > > > > A woman on the ImmuneSuppport CFS discussion board who is

> on the

> > > > > > simplified treatment approach for lifting the methylation

> cycle

> > > > > block

> > > > > > just reported that she was able to stop

> > > > > > her use of desmopressin (which she had been using since last

> > > > > > September to control her heavy urine volume), and her urine

> volume

> > > > > > did not jump back up, as it formerly did when she stopped

> the

> > > > > > desmopressin. I think this agrees with Hall's report

> some

> > > > time

> > > > > > ago that restoring his glutathione level corrected his

> diabetes

> > > > > > insipidus, too. Here is the response I wrote to this woman.

> I took

> > > > > > her name off to protect her privacy, but she posted to a

> public

> > > > > > discussion board, and you can read her post there.

> > > > > >

> > > > > > Rich

> > > > > >

> > > > > >

> > > > > > Hi, _______.

> > > > > >

> > > > > > This is wonderful! It's wonderful both for you and for me

> and for

> > > > > the

> > > > > > whole CFS community, because it provides more observational

> > > > support

> > > > > > for the GD-MCB hypothesis.

> > > > > >

> > > > > > As you probably know (but I want to make sure other readers

> are

> > > > > aware

> > > > > > of it, too), part of this hypothesis says that the low

> production

> > > > of

> > > > > > antidiuretic hormone (also called arginine vasopressin) in

> CFS

> > > > > > results from low glutathione in the hypothalamus. This

> results in

> > > > a

> > > > > > (usually mild) case of diabetes insipidus, not to be

> confused with

> > > > > > diabetes mellitus, which involves high blood sugar and low

> > > > insulin.

> > > > > >

> > > > > > " Diabetes " means you have a lot of urine. " Mellitus " means

> your

> > > > > urine

> > > > > > tastes sweet, because it has elevated blood sugar or

> glucose in

> > > > > > it. " Insipidus " means that your urine tastes insipid, i.e.

> it

> > > > isn't

> > > > > > sweet. Not many people like to diagnose these by tasting

> the urine

> > > > > > these days, but it's much quicker than doing the lab tests!

> (:-)).

> > > > > >

> > > > > > Diabetes insipidus produces high urine volume and low total

> blood

> > > > > > volume, as well as constant thirst. This is the phenomenon

> in CFS

> > > > > > that Dr. Teitelbaum refers to as " Pee like a racehorse,

> drink

> > > > like a

> > > > > > fish. "

> > > > > >

> > > > > > The simplified treatment approach, among other things, is

> > > > designed

> > > > > to

> > > > > > allow glutathione levels to come up to normal. When this

> happens,

> > > > we

> > > > > > should expect that the diabetes insipidus will disappear,

> and you

> > > > > > have verified that it did in your case.

> > > > > >

> > > > > > I should make a small correction to what you wrote, in that

> while

> > > > > > this does involve the hypothalamus, it doesn't actually say

> that

> > > > the

> > > > > > HPA (hypothalamus-pituitary-adrenal) axis has been restored

> to

> > > > > normal

> > > > > > operation. I expect that that will occur as well, but the

> > > > > > disappearance of the diabetes insipidus does not prove

> that.

> > > > > Evidence

> > > > > > for improvement in the HPA axis would include things like

> blood

> > > > > > pressure coming up to normal, decrease in symptoms of

> > > > hypoglycemia,

> > > > > > cortisol and DHEA levels restored to normal, disappearance

> of

> > > > > > orthostatic problems such as problems with blood pressure

> or heart

> > > > > > rate when standing, better ability to cope with stress of

> all

> > > > sorts,

> > > > > > and other cortisol-related things. If you are observing

> those

> > > > things

> > > > > > as well, then I would agree that your HPA axis is doing

> better,

> > > > too.

> > > > > > I fully expect that to happen for you, too, if it hasn't

> already,

> > > > > > because the same basic mechanism in the biochemistry that

> restored

> > > > > > ADH should also restore ACTH, which I think will bring the

> HPA

> > > > axis

> > > > > > back to normal operation.

> > > > > >

> > > > > > At the biochemical level, I think this observation also

> supports

> > > > my

> > > > > > more fundamental suggestion that secretory proteins that

> contain

> > > > > > cysteine double bonds are not being made well in CFS

> because of

> > > > > > glutathione depletion in the cells in which they are made.

> If

> > > > this

> > > > > is

> > > > > > true, it also provides support for my hypotheses to explain

> low

> > > > > > levels of some of the other secretory proteins in CFS,

> including

> > > > > > human growth hormone, ACTH, oxytocin, perforin, and

> probably some

> > > > > > others as well. So this is big, from my point of view!

> > > > > >

> > > > > > Thank you so much for posting this, and keep on keeping on!

> > > > > >

> > > > > > Rich

> > > > > >

> > > > >

> > > >

> > >

> >

>

[Guest guest]

We talk about pseudomonas quite a bit here. It's one of my co-infections and very difficult to beat. The literature almost always says one anti-microbial agent (abx) is not enough. penny kdrbrill <kdrbrill@...> wrote: Been saving up $ to see this doc -- a naturopath who specializes in CFS -- for more than a year. She uses a variety of labs that specialize in different areas.She ordered a CSDA (stool test) from Meridian Valley -- they

actually grow the bugs rather than just looking for antigens. Found no parasites this time, but the "non-candida yeast" and higher levels of pseudomonas.I had never heard of pseudomonas before, so was surprised as well. Pseudos can be a player in someone with CFS:http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed & list_uids=17007934 & cmd=Retrieve & indexed=googleThanks Tony -- and thanks for not screaming! :)Dan> > > > > >> > > > > > Hi, all.> > > > > > > > > > > > I know that some folks here would prefer that I not post > things > > > > > about> > > > > > the methylation cycle block treatment on this list, but > please> > > > > > forgive me for this one. I think it's a biggie, and I think> > > > > > everybody here should hear about it.> > > > > > > > > > > > A woman on the ImmuneSuppport CFS discussion board who is > on the> > > > > > simplified treatment approach for lifting the methylation

> cycle > > > > > block> > > > > > just reported that she was able to stop> > > > > > her use of desmopressin (which she had been using since last> > > > > > September to control her heavy urine volume), and her urine > volume> > > > > > did not jump back up, as it formerly did when she stopped > the> > > > > > desmopressin. I think this agrees with Hall's report > some > > > > time> > > > > > ago that restoring his glutathione level corrected his > diabetes> > > > > > insipidus, too. Here is the response I wrote to this woman. > I took> > > > > > her name off to protect her privacy, but she posted to a > public> > > > > > discussion board, and you can read her post there.> > >

> > > > > > > > > Rich> > > > > > > > > > > > > > > > > > Hi, _______.> > > > > > > > > > > > This is wonderful! It's wonderful both for you and for me > and for > > > > > the> > > > > > whole CFS community, because it provides more observational > > > > support> > > > > > for the GD-MCB hypothesis.> > > > > > > > > > > > As you probably know (but I want to make sure other readers > are > > > > > aware> > > > > > of it, too), part of this hypothesis says that the low > production > > > > of> > > > > > antidiuretic hormone (also called arginine vasopressin) in > CFS> > > > > > results

from low glutathione in the hypothalamus. This > results in > > > > a> > > > > > (usually mild) case of diabetes insipidus, not to be > confused with> > > > > > diabetes mellitus, which involves high blood sugar and low > > > > insulin.> > > > > > > > > > > > "Diabetes" means you have a lot of urine. "Mellitus" means > your > > > > > urine> > > > > > tastes sweet, because it has elevated blood sugar or > glucose in> > > > > > it. "Insipidus" means that your urine tastes insipid, i.e. > it > > > > isn't> > > > > > sweet. Not many people like to diagnose these by tasting > the urine> > > > > > these days, but it's much quicker than doing the lab tests! > (:-)).> > > > >

> > > > > > > Diabetes insipidus produces high urine volume and low total > blood> > > > > > volume, as well as constant thirst. This is the phenomenon > in CFS> > > > > > that Dr. Teitelbaum refers to as "Pee like a racehorse, > drink > > > > like a> > > > > > fish."> > > > > > > > > > > > The simplified treatment approach, among other things, is > > > > designed > > > > > to> > > > > > allow glutathione levels to come up to normal. When this > happens, > > > > we> > > > > > should expect that the diabetes insipidus will disappear, > and you> > > > > > have verified that it did in your case.> > > > > > > > > > > > I should make a

small correction to what you wrote, in that > while> > > > > > this does involve the hypothalamus, it doesn't actually say > that > > > > the> > > > > > HPA (hypothalamus-pituitary-adrenal) axis has been restored > to > > > > > normal> > > > > > operation. I expect that that will occur as well, but the> > > > > > disappearance of the diabetes insipidus does not prove > that. > > > > > Evidence> > > > > > for improvement in the HPA axis would include things like > blood> > > > > > pressure coming up to normal, decrease in symptoms of > > > > hypoglycemia,> > > > > > cortisol and DHEA levels restored to normal, disappearance > of> > > > > > orthostatic problems such as problems with

blood pressure > or heart> > > > > > rate when standing, better ability to cope with stress of > all > > > > sorts,> > > > > > and other cortisol-related things. If you are observing > those > > > > things> > > > > > as well, then I would agree that your HPA axis is doing > better, > > > > too.> > > > > > I fully expect that to happen for you, too, if it hasn't > already,> > > > > > because the same basic mechanism in the biochemistry that > restored> > > > > > ADH should also restore ACTH, which I think will bring the > HPA > > > > axis> > > > > > back to normal operation.> > > > > > > > > > > > At the biochemical level, I think this observation also >

supports > > > > my> > > > > > more fundamental suggestion that secretory proteins that > contain> > > > > > cysteine double bonds are not being made well in CFS > because of> > > > > > glutathione depletion in the cells in which they are made. > If > > > > this > > > > > is> > > > > > true, it also provides support for my hypotheses to explain > low> > > > > > levels of some of the other secretory proteins in CFS, > including> > > > > > human growth hormone, ACTH, oxytocin, perforin, and > probably some> > > > > > others as well. So this is big, from my point of view!> > > > > > > > > > > > Thank you so much for posting this, and keep on keeping on!> > > > > >

> > > > > > Rich> > > > > >> > > > >> > > >> > >> >>

[Guest guest]

I encourage you to look at the link on the east indian herbal remedy again...it

killed it,

destroyed the (usually difficult to destroy) outer membrane that it uses to

protect itself.

http://cfvancouver.ca/cms/index.php?option=com_content & task=view & id=63 & Itemid=38

d.

> > > > > > >

> > > > > > > Hi, all.

> > > > > > >

> > > > > > > I know that some folks here would prefer that I not post

> > things

> > > > > > about

> > > > > > > the methylation cycle block treatment on this list, but

> > please

> > > > > > > forgive me for this one. I think it's a biggie, and I think

> > > > > > > everybody here should hear about it.

> > > > > > >

> > > > > > > A woman on the ImmuneSuppport CFS discussion board who is

> > on the

> > > > > > > simplified treatment approach for lifting the methylation

> > cycle

> > > > > > block

> > > > > > > just reported that she was able to stop

> > > > > > > her use of desmopressin (which she had been using since last

> > > > > > > September to control her heavy urine volume), and her urine

> > volume

> > > > > > > did not jump back up, as it formerly did when she stopped

> > the

> > > > > > > desmopressin. I think this agrees with Hall's report

> > some

> > > > > time

> > > > > > > ago that restoring his glutathione level corrected his

> > diabetes

> > > > > > > insipidus, too. Here is the response I wrote to this woman.

> > I took

> > > > > > > her name off to protect her privacy, but she posted to a

> > public

> > > > > > > discussion board, and you can read her post there.

> > > > > > >

> > > > > > > Rich

> > > > > > >

> > > > > > >

> > > > > > > Hi, _______.

> > > > > > >

> > > > > > > This is wonderful! It's wonderful both for you and for me

> > and for

> > > > > > the

> > > > > > > whole CFS community, because it provides more observational

> > > > > support

> > > > > > > for the GD-MCB hypothesis.

> > > > > > >

> > > > > > > As you probably know (but I want to make sure other readers

> > are

> > > > > > aware

> > > > > > > of it, too), part of this hypothesis says that the low

> > production

> > > > > of

> > > > > > > antidiuretic hormone (also called arginine vasopressin) in

> > CFS

> > > > > > > results from low glutathione in the hypothalamus. This

> > results in

> > > > > a

> > > > > > > (usually mild) case of diabetes insipidus, not to be

> > confused with

> > > > > > > diabetes mellitus, which involves high blood sugar and low

> > > > > insulin.

> > > > > > >

> > > > > > > " Diabetes " means you have a lot of urine. " Mellitus " means

> > your

> > > > > > urine

> > > > > > > tastes sweet, because it has elevated blood sugar or

> > glucose in

> > > > > > > it. " Insipidus " means that your urine tastes insipid, i.e.

> > it

> > > > > isn't

> > > > > > > sweet. Not many people like to diagnose these by tasting

> > the urine

> > > > > > > these days, but it's much quicker than doing the lab tests!

> > (:-)).

> > > > > > >

> > > > > > > Diabetes insipidus produces high urine volume and low total

> > blood

> > > > > > > volume, as well as constant thirst. This is the phenomenon

> > in CFS

> > > > > > > that Dr. Teitelbaum refers to as " Pee like a racehorse,

> > drink

> > > > > like a

> > > > > > > fish. "

> > > > > > >

> > > > > > > The simplified treatment approach, among other things, is

> > > > > designed

> > > > > > to

> > > > > > > allow glutathione levels to come up to normal. When this

> > happens,

> > > > > we

> > > > > > > should expect that the diabetes insipidus will disappear,

> > and you

> > > > > > > have verified that it did in your case.

> > > > > > >

> > > > > > > I should make a small correction to what you wrote, in that

> > while

> > > > > > > this does involve the hypothalamus, it doesn't actually say

> > that

> > > > > the

> > > > > > > HPA (hypothalamus-pituitary-adrenal) axis has been restored

> > to

> > > > > > normal

> > > > > > > operation. I expect that that will occur as well, but the

> > > > > > > disappearance of the diabetes insipidus does not prove

> > that.

> > > > > > Evidence

> > > > > > > for improvement in the HPA axis would include things like

> > blood

> > > > > > > pressure coming up to normal, decrease in symptoms of

> > > > > hypoglycemia,

> > > > > > > cortisol and DHEA levels restored to normal, disappearance

> > of

> > > > > > > orthostatic problems such as problems with blood pressure

> > or heart

> > > > > > > rate when standing, better ability to cope with stress of

> > all

> > > > > sorts,

> > > > > > > and other cortisol-related things. If you are observing

> > those

> > > > > things

> > > > > > > as well, then I would agree that your HPA axis is doing

> > better,

> > > > > too.

> > > > > > > I fully expect that to happen for you, too, if it hasn't

> > already,

> > > > > > > because the same basic mechanism in the biochemistry that

> > restored

> > > > > > > ADH should also restore ACTH, which I think will bring the

> > HPA

> > > > > axis

> > > > > > > back to normal operation.

> > > > > > >

> > > > > > > At the biochemical level, I think this observation also

> > supports

> > > > > my

> > > > > > > more fundamental suggestion that secretory proteins that

> > contain

> > > > > > > cysteine double bonds are not being made well in CFS

> > because of

> > > > > > > glutathione depletion in the cells in which they are made.

> > If

> > > > > this

> > > > > > is

> > > > > > > true, it also provides support for my hypotheses to explain

> > low

> > > > > > > levels of some of the other secretory proteins in CFS,

> > including

> > > > > > > human growth hormone, ACTH, oxytocin, perforin, and

> > probably some

> > > > > > > others as well. So this is big, from my point of view!

> > > > > > >

> > > > > > > Thank you so much for posting this, and keep on keeping on!

> > > > > > >

> > > > > > > Rich

> > > > > > >

> > > > > >

> > > > >

> > > >

> > >

> >

>

[Guest guest]

Yes, definitely will consider trying it. That would be great if it can eradicate pseudomonas. Pseudomonas is a big problem for horses so it could have a lot of applications. Even if people are a bit too short sighted to recognize it as a threat, at least horses could possibly benefit. Barb, have you heard of this? pennykdrbrill <kdrbrill@...> wrote: I encourage you to look at the link on the east indian herbal remedy again...it killed it, destroyed the (usually difficult to

destroy) outer membrane that it uses to protect itself.http://cfvancouver.ca/cms/index.php?option=com_content & task=view & id=63 & Itemid=38d. > > > > > > >> > > > > > > Hi, all.> > > > > > > > > >

> > > > I know that some folks here would prefer that I not post > > things > > > > > > about> > > > > > > the methylation cycle block treatment on this list, but > > please> > > > > > > forgive me for this one. I think it's a biggie, and I think> > > > > > > everybody here should hear about it.> > > > > > > > > > > > > > A woman on the ImmuneSuppport CFS discussion board who is > > on the> > > > > > > simplified treatment approach for lifting the methylation > > cycle > > > > > > block> > > > > > > just reported that she was able to stop> > > > > > > her use of desmopressin (which she had been using since last> > > > > > > September to control her heavy

urine volume), and her urine > > volume> > > > > > > did not jump back up, as it formerly did when she stopped > > the> > > > > > > desmopressin. I think this agrees with Hall's report > > some > > > > > time> > > > > > > ago that restoring his glutathione level corrected his > > diabetes> > > > > > > insipidus, too. Here is the response I wrote to this woman. > > I took> > > > > > > her name off to protect her privacy, but she posted to a > > public> > > > > > > discussion board, and you can read her post there.> > > > > > > > > > > > > > Rich> > > > > > > > > > > > > > > > > > > > > Hi, _______.> > > >

> > > > > > > > > > This is wonderful! It's wonderful both for you and for me > > and for > > > > > > the> > > > > > > whole CFS community, because it provides more observational > > > > > support> > > > > > > for the GD-MCB hypothesis.> > > > > > > > > > > > > > As you probably know (but I want to make sure other readers > > are > > > > > > aware> > > > > > > of it, too), part of this hypothesis says that the low > > production > > > > > of> > > > > > > antidiuretic hormone (also called arginine vasopressin) in > > CFS> > > > > > > results from low glutathione in the hypothalamus. This > > results in > > > > >

a> > > > > > > (usually mild) case of diabetes insipidus, not to be > > confused with> > > > > > > diabetes mellitus, which involves high blood sugar and low > > > > > insulin.> > > > > > > > > > > > > > "Diabetes" means you have a lot of urine. "Mellitus" means > > your > > > > > > urine> > > > > > > tastes sweet, because it has elevated blood sugar or > > glucose in> > > > > > > it. "Insipidus" means that your urine tastes insipid, i.e. > > it > > > > > isn't> > > > > > > sweet. Not many people like to diagnose these by tasting > > the urine> > > > > > > these days, but it's much quicker than doing the lab tests! > > (:-)).> > > > > >

> > > > > > > > Diabetes insipidus produces high urine volume and low total > > blood> > > > > > > volume, as well as constant thirst. This is the phenomenon > > in CFS> > > > > > > that Dr. Teitelbaum refers to as "Pee like a racehorse, > > drink > > > > > like a> > > > > > > fish."> > > > > > > > > > > > > > The simplified treatment approach, among other things, is > > > > > designed > > > > > > to> > > > > > > allow glutathione levels to come up to normal. When this > > happens, > > > > > we> > > > > > > should expect that the diabetes insipidus will disappear, > > and you> > > > > > > have verified that it did in your

case.> > > > > > > > > > > > > > I should make a small correction to what you wrote, in that > > while> > > > > > > this does involve the hypothalamus, it doesn't actually say > > that > > > > > the> > > > > > > HPA (hypothalamus-pituitary-adrenal) axis has been restored > > to > > > > > > normal> > > > > > > operation. I expect that that will occur as well, but the> > > > > > > disappearance of the diabetes insipidus does not prove > > that. > > > > > > Evidence> > > > > > > for improvement in the HPA axis would include things like > > blood> > > > > > > pressure coming up to normal, decrease in symptoms of > > > > >

hypoglycemia,> > > > > > > cortisol and DHEA levels restored to normal, disappearance > > of> > > > > > > orthostatic problems such as problems with blood pressure > > or heart> > > > > > > rate when standing, better ability to cope with stress of > > all > > > > > sorts,> > > > > > > and other cortisol-related things. If you are observing > > those > > > > > things> > > > > > > as well, then I would agree that your HPA axis is doing > > better, > > > > > too.> > > > > > > I fully expect that to happen for you, too, if it hasn't > > already,> > > > > > > because the same basic mechanism in the biochemistry that > > restored> > > > > > > ADH should also

restore ACTH, which I think will bring the > > HPA > > > > > axis> > > > > > > back to normal operation.> > > > > > > > > > > > > > At the biochemical level, I think this observation also > > supports > > > > > my> > > > > > > more fundamental suggestion that secretory proteins that > > contain> > > > > > > cysteine double bonds are not being made well in CFS > > because of> > > > > > > glutathione depletion in the cells in which they are made. > > If > > > > > this > > > > > > is> > > > > > > true, it also provides support for my hypotheses to explain > > low> > > > > > > levels of some of the other secretory proteins in CFS, > >

including> > > > > > > human growth hormone, ACTH, oxytocin, perforin, and > > probably some> > > > > > > others as well. So this is big, from my point of view!> > > > > > > > > > > > > > Thank you so much for posting this, and keep on keeping on!> > > > > > > > > > > > > > Rich> > > > > > >> > > > > >> > > > >> > > >> > >> >>

[Guest guest]

>>>>Thanks Tony -- and thanks for not screaming! <<<<

Dan

The reason why these types of forums exist, is because we have been

programmed in society to do things a certain way. I learnt that if

you don't scream, like we do more of here in australia, the people

that make the rules will SCREW YOU.. Society is heading in a

direction wherby you are not seeing what your seeing, your suppoosed

to be seeing something else.In every facet of daily life the people

making the bucks are putting blinkers on everyone around them so that

they can keep bringing home the bacon. I recommend more people should

honestlky take up screaming whenever these types of injustices are

practised on you.How rediculous is it that you have a stiff neck and

spine and you have to sit with a psych doctor that assures you he

knows what is going wrong?What sort of a wank is it that society has

given these people powers, in some cases above the law.

> > > > > > >

> > > > > > > Hi, all.

> > > > > > >

> > > > > > > I know that some folks here would prefer that I not

post

> > things

> > > > > > about

> > > > > > > the methylation cycle block treatment on this list, but

> > please

> > > > > > > forgive me for this one. I think it's a biggie, and I

think

> > > > > > > everybody here should hear about it.

> > > > > > >

> > > > > > > A woman on the ImmuneSuppport CFS discussion board who

is

> > on the

> > > > > > > simplified treatment approach for lifting the

methylation

> > cycle

> > > > > > block

> > > > > > > just reported that she was able to stop

> > > > > > > her use of desmopressin (which she had been using since

last

> > > > > > > September to control her heavy urine volume), and her

urine

> > volume

> > > > > > > did not jump back up, as it formerly did when she

stopped

> > the

> > > > > > > desmopressin. I think this agrees with Hall's

report

> > some

> > > > > time

> > > > > > > ago that restoring his glutathione level corrected his

> > diabetes

> > > > > > > insipidus, too. Here is the response I wrote to this

woman.

> > I took

> > > > > > > her name off to protect her privacy, but she posted to

a

> > public

> > > > > > > discussion board, and you can read her post there.

> > > > > > >

> > > > > > > Rich

> > > > > > >

> > > > > > >

> > > > > > > Hi, _______.

> > > > > > >

> > > > > > > This is wonderful! It's wonderful both for you and for

me

> > and for

> > > > > > the

> > > > > > > whole CFS community, because it provides more

observational

> > > > > support

> > > > > > > for the GD-MCB hypothesis.

> > > > > > >

> > > > > > > As you probably know (but I want to make sure other

readers

> > are

> > > > > > aware

> > > > > > > of it, too), part of this hypothesis says that the low

> > production

> > > > > of

> > > > > > > antidiuretic hormone (also called arginine vasopressin)

in

> > CFS

> > > > > > > results from low glutathione in the hypothalamus. This

> > results in

> > > > > a

> > > > > > > (usually mild) case of diabetes insipidus, not to be

> > confused with

> > > > > > > diabetes mellitus, which involves high blood sugar and

low

> > > > > insulin.

> > > > > > >

> > > > > > > " Diabetes " means you have a lot of urine. " Mellitus "

means

> > your

> > > > > > urine

> > > > > > > tastes sweet, because it has elevated blood sugar or

> > glucose in

> > > > > > > it. " Insipidus " means that your urine tastes insipid,

i.e.

> > it

> > > > > isn't

> > > > > > > sweet. Not many people like to diagnose these by

tasting

> > the urine

> > > > > > > these days, but it's much quicker than doing the lab

tests!

> > (:-)).

> > > > > > >

> > > > > > > Diabetes insipidus produces high urine volume and low

total

> > blood

> > > > > > > volume, as well as constant thirst. This is the

phenomenon

> > in CFS

> > > > > > > that Dr. Teitelbaum refers to as " Pee like a racehorse,

> > drink

> > > > > like a

> > > > > > > fish. "

> > > > > > >

> > > > > > > The simplified treatment approach, among other things,

is

> > > > > designed

> > > > > > to

> > > > > > > allow glutathione levels to come up to normal. When

this

> > happens,

> > > > > we

> > > > > > > should expect that the diabetes insipidus will

disappear,

> > and you

> > > > > > > have verified that it did in your case.

> > > > > > >

> > > > > > > I should make a small correction to what you wrote, in

that

> > while

> > > > > > > this does involve the hypothalamus, it doesn't actually

say

> > that

> > > > > the

> > > > > > > HPA (hypothalamus-pituitary-adrenal) axis has been

restored

> > to

> > > > > > normal

> > > > > > > operation. I expect that that will occur as well, but

the

> > > > > > > disappearance of the diabetes insipidus does not prove

> > that.

> > > > > > Evidence

> > > > > > > for improvement in the HPA axis would include things

like

> > blood

> > > > > > > pressure coming up to normal, decrease in symptoms of

> > > > > hypoglycemia,

> > > > > > > cortisol and DHEA levels restored to normal,

disappearance

> > of

> > > > > > > orthostatic problems such as problems with blood

pressure

> > or heart

> > > > > > > rate when standing, better ability to cope with stress

of

> > all

> > > > > sorts,

> > > > > > > and other cortisol-related things. If you are observing

> > those

> > > > > things

> > > > > > > as well, then I would agree that your HPA axis is doing

> > better,

> > > > > too.

> > > > > > > I fully expect that to happen for you, too, if it

hasn't

> > already,

> > > > > > > because the same basic mechanism in the biochemistry

that

> > restored

> > > > > > > ADH should also restore ACTH, which I think will bring

the

> > HPA

> > > > > axis

> > > > > > > back to normal operation.

> > > > > > >

> > > > > > > At the biochemical level, I think this observation also

> > supports

> > > > > my

> > > > > > > more fundamental suggestion that secretory proteins

that

> > contain

> > > > > > > cysteine double bonds are not being made well in CFS

> > because of

> > > > > > > glutathione depletion in the cells in which they are

made.

> > If

> > > > > this

> > > > > > is

> > > > > > > true, it also provides support for my hypotheses to

explain

> > low

> > > > > > > levels of some of the other secretory proteins in CFS,

> > including

> > > > > > > human growth hormone, ACTH, oxytocin, perforin, and

> > probably some

> > > > > > > others as well. So this is big, from my point of view!

> > > > > > >

> > > > > > > Thank you so much for posting this, and keep on keeping

on!

> > > > > > >

> > > > > > > Rich

> > > > > > >

> > > > > >

> > > > >

> > > >

> > >

> >

>