RE: News alert on Nutrivene-website: new DS/supplement study

November 22, 2008

It is an interesting pilot study. However, reading beyond the abstract, it does

not appear to offer a reliable standard of evidence supportive of

supplementation to improve developmental outcomes.

Remarkably, the paper completely fails to describe the cognitive assessment

methods used and does not disclose any actual results that support the statement

that " psychological assessment... revealed significant improvement in cognitive

skills " . In the absence of that information, the authors cannot sustain their

conclusion.

Interestingly, Nutrivene makes no note of the limitations of the study on its

home page and has dropped the word " pilot " when copying and pasting the

abstract.

By contrast, the clearest and most reliable examination of developmental and

health outcomes with/without antioxidant/folate supplementation (to date)

details its methods and fully reports its results. It offers a higher standard

of evidence because it was a randomized controlled trial involving a larger

study population:

It found no significant differences in developmental outcomes between treatments

and placebo groups and no difference in markers of oxidative stress that

(according to claims for TNI) is the prime target of supplementation.

[DownSyndromeInfoExchange] News alert on Nutrivene-website: new

DS/supplement study

Study Shows Benefits of Nutritional Supplementation in Down Syndrome

A new study of children with Down syndrome shows significant

improvement in cognitive skills and behavior after nutritional

supplementation with antioxidants, vitamins, and minerals.

....

______________________________________________________________________

Down Syndrome Education International http://www.downsed.org/

Down Syndrome Education USA http://www.downsed-usa.org/

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