Guest guest Posted November 3, 2007 Report Share Posted November 3, 2007 No big news there, Roy. It's the same stuff I reported for myself many times. Fewer headaches, less pain, less head pressure, less anxiety, even less bladder pressure. Benicar was a remarkable symptom reliever for me, but it also created problems of its own. And the symptom relief doesn't prove that it's fighting infection or curing this illness. If it's safe, it could possibl7 slow down the damage being done by inflammation. I'm beginning to strongly suspect that the Benicar was relieving symptoms caused by my particular genetic coagulation disorders. One of these mutations creates an inability to synthesize Nitric Oxide (the Endothelial Nitric Oxide Synthase (eNOS) Mutation). This mutation can cause spasmodic muscle contraction of the blood vessel walls, such as those that happen during migraines and probably many other painful inflammatory conditions. It makes a lot of sense to me, that since Benicar is first and foremost a BLOOD PRESSURE medication and that it clearly relaxes BLOOD VESSELS (which is how blood pressure is lowered) that it would also relieve symptoms caused by any kind of blood vessel spasm and inflammation, such as those caused by gene mutaions like the eNOS one I mentioned above. Interestingly many of those symptoms are identical to (and probably interdependent with) the symptoms caused by infection. It gets even more interesting when you realize that Nitric Oxide not only acts on the blood vessels, it aids the immune system in fighting infections. According to research, many organisms become resistant to Nitric Oxide. If you're not synthesizing NO properly, it not only causes muscle contraction and pain, it's not able to do its job as an antimicrobial. It would only make sense that a break down in synthesis could possibly give the bugs the upper hand. That of course would only compound the hypercoagulation and inflammation issues and result in progressively worsening symptoms. Since Benicar can relax those spasming blood vessels, it follows that symptoms are going to be eased as well. And eNOS is not the only mutation that acts on blood vessels. This is just a theory, but it could also explain why Benicar is miraculous for some, and not at all helpful for others. penny royx31 <roysno@...> wrote: Greg Blaney, M.D. is interviewed here:http://tinyurl.com/2af3sfWhat conditions have you seen respond to the MP?"I've had people with numerous inflammatory conditions do very well on the MP. I've had patients with arthritis, fibromyalgia, cardiovascular disorders, hypertension, Raynaud's syndrome, Chronic Obstructive Pulmonary Disorder (COPD), chronic headaches and migraines, and other diseases respond very well. I've also had patients with mental afflictions such as obsessive compulsive disorder, anxiety disorders and depression do very well.""The patients that have the most spectacular initial responses to the MP are often those with severe headaches."just FYI,Roy Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 5, 2007 Report Share Posted November 5, 2007 Thank you, Roy. I have great respect for Dr. Blaney. In my case I certainly have not been able to rule out infection. I just got a statement from an MD reguarding infection causing increased glutamate due to increased quinolinic acid causing oxidative stress and excitotoxicity. Hopefully - whatever is going on in my brain - the high dose of penicillin VK will fix things along with the Lyrica. My doctor and I have talked about adding Benicar back in. We shall see. Right now I am very much an experiment in progress. I did try minocycline and Zithromax for a few weeks each with no effect at all on the headache this past 17 months. So, for now, it looks like the penicillin is the way to go. In any case it is nice to be able to think for now, and nice to hear from you. a Carnes > > Greg Blaney, M.D. is interviewed here: > http://tinyurl.com/2af3sf > > What conditions have you seen respond to the MP? > " I've had people with numerous inflammatory conditions do very well > on the MP. I've had patients with arthritis, fibromyalgia, > cardiovascular disorders, hypertension, Raynaud's syndrome, Chronic > Obstructive Pulmonary Disorder (COPD), chronic headaches and > migraines, and other diseases respond very well. I've also had > patients with mental afflictions such as obsessive compulsive > disorder, anxiety disorders and depression do very well. " > > " The patients that have the most spectacular initial responses to the > MP are often those with severe headaches. " > > just FYI, > Roy > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 12, 2007 Report Share Posted November 12, 2007 a, The penicillin you are taking is a beta-lactam. From the interview: " Now, I also realize that many of the antibiotics used by doctors that follow these recommendations actually foster the growth of L-form bacteria (the beta-lactam antibiotics). " Greg Blaney M.D. TX Lyme Mom and Trevor replied to Penny on the MP web site when she switched to a beta-lactam which was Ceftin, if memory serves. They both explained that it would cause the CWD bacteria to lose their cell walls and would cause symptomatic improvement without killing the bacteria. I don't expect you to believe me, but I think you should get more expert opinions. I would be extremely hesitant to add Benicar to your other drugs, since it potentiates some antibiotics tremendously, and others are unpredictable. Barb got me curious about virgin coconut oil, and I tried less than 1 teaspoon last summer. It took several days for the extra effects like fatigue and brain fog to wear off, but it was delicious. :-) I reacted very strongly to a couple cloves of garlic after two weeks on the Benicar. I even reacted to onions and cut them out of my diet for a year. I can eat both of those now without any problem. Adding prescription antibiotics seems to me to be playing Russian roulette. The warning to not add other antibiotics to the MP without checking with the moderators is justified. Roy > > Thank you, Roy. > I have great respect for Dr. Blaney. In my case I certainly have not > been able to rule out infection. I just got a statement from an MD > reguarding infection causing increased glutamate due to increased > quinolinic acid causing oxidative stress and excitotoxicity. > Hopefully - whatever is going on in my brain - the high dose of > penicillin VK will fix things along with the Lyrica. My doctor and I > have talked about adding Benicar back in. We shall see. Right now I > am very much an experiment in progress. I did try minocycline and > Zithromax for a few weeks each with no effect at all on the headache > this past 17 months. So, for now, it looks like the penicillin is the > way to go. In any case it is nice to be able to think for now, and > nice to hear from you. > > a Carnes > > > > > > Greg Blaney, M.D. is interviewed here: > > http://tinyurl.com/2af3sf > > > > What conditions have you seen respond to the MP? > > " I've had people with numerous inflammatory conditions do very > well > > on the MP. I've had patients with arthritis, fibromyalgia, > > cardiovascular disorders, hypertension, Raynaud's syndrome, Chronic > > Obstructive Pulmonary Disorder (COPD), chronic headaches and > > migraines, and other diseases respond very well. I've also had > > patients with mental afflictions such as obsessive compulsive > > disorder, anxiety disorders and depression do very well. " > > > > " The patients that have the most spectacular initial responses to > the > > MP are often those with severe headaches. " > > > > just FYI, > > Roy > > > Quote Link to comment Share on other sites More sharing options...
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