Guest guest Posted August 16, 2007 Report Share Posted August 16, 2007 Do your tests indicate you're defecient in iron? My most recent spectra cell tests show me to be defecient in 3 of the Bs, D and zinc. Also asparagine, which I haven't been able to find at my health food store. I had a hair analysis done by Dr. some years back which showed me to be defecient in every single mineral. The guy who helped me with my supplementation told me he'd never seen such defeciencies in a living person. Unfortunately, extreme supplementing didn't really help me feel any better. There were a few exceptions here and there (bs, magnesium, chromium), which I'm grateful to have learned about, but in general it was a lot of effort and tremendous expense with little result. penny kdrbrill <kdrbrill@...> wrote: Not on CFS patients, but...interesting...1: Am J Clin Nutr. 2004 Mar;79(3):516-21.Click here to read LinksImmune function is impaired in iron-deficient, homebound, older women.Ahluwalia N, Sun J, Krause D, Mastro A, Handte G.Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802, USA.BACKGROUND: Aging is often associated with a dysregulation of immune function. Iron deficiency may further impair immunity in older adults. Published reports on iron deficiency and immune response in humans are inconsistent. Most studies are focused on young children in developing countries and are often confounded by comorbid conditions, infections, and nutrient deficiencies. OBJECTIVE: Our objective was to determine the relation of iron status with immune function in homebound older women, who often have impairments in both iron status and immune response. The subjects were selected according to rigorous exclusion criteria for disease, infection, and deficiencies in key nutrients known to affect immunocompetence. DESIGN: Seventy-two homebound elderly women provided blood for comprehensive evaluation of iron status and cell-mediated and innate immunity. Women were classified as iron-deficient or iron-sufficient on the basis of multiple abnormal iron status test results. Groups were compared with respect to lymphocyte subsets, phagocytosis, oxidative burst capacity, and T cell proliferation upon stimulation with mitogens. RESULTS: In iron-deficient women, T cell proliferation upon stimulation with concanavalin A and phytohemagglutinin A was only 40-50% of that in iron-sufficient women. Phagocytosis did not differ significantly between the 2 groups, but respiratory burst was significantly less (by 28%) in iron-deficient women than in iron-sufficient women. CONCLUSIONS: Iron deficiency is associated with impairments in cell-mediated and innate immunity and may render older adults more vulnerable to infections. Further prospective studies using similar exclusion criteria for disease, infection, and concomitant nutrient deficiencies are needed for simultaneous examination of the effects of iron deficiency on immune response and morbidity. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 16, 2007 Report Share Posted August 16, 2007 WOW! Your ferratin was 53???? Mine was 8 at one point! Crap! LOL! But, now I've had endometrial ablation and I find out next Thursday what my ferratin is up to now. I also have MS, so I'm wondering about the Immune issue. KLSGet a sneak peek of the all-new AOL.com. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 16, 2007 Report Share Posted August 16, 2007 Hi Penny, Haven't had a ferritin test in awhile -- think the last one was 53-ish or so -- kind of the low-end of " normal " . Wish I could afford that spectra-cell testing... I just know that in the past -- whenever I've taken iron -- along with other co-factors (Very important as you say) -- I've " recovered " , at least for 9 months to a year or so. But I've been spooked into worrying that it might worsen things...so am more cautious lately. I did the testing as well -- probably four years ago. I was okay in most things exceept trace minerals (almost absent) and my potassium was HIGH, sodium very low. Worn out adrenals, they said..................? d > Not on CFS patients, but...interesting... > > 1: Am J Clin Nutr. 2004 Mar;79(3):516-21.Click here to read Links > Immune function is impaired in iron-deficient, homebound, older women. > Ahluwalia N, Sun J, Krause D, Mastro A, Handte G. > > Department of Nutritional Sciences, The Pennsylvania State University, University Park, > PA 16802, USA. > > BACKGROUND: Aging is often associated with a dysregulation of immune function. Iron > deficiency may further impair immunity in older adults. Published reports on iron > deficiency and immune response in humans are inconsistent. Most studies are focused on > young children in developing countries and are often confounded by comorbid conditions, > infections, and nutrient deficiencies. > > OBJECTIVE: Our objective was to determine the relation of iron status with immune > function in homebound older women, who often have impairments in both iron status and > immune response. The subjects were selected according to rigorous exclusion criteria for > disease, infection, and deficiencies in key nutrients known to affect immunocompetence. > > DESIGN: Seventy-two homebound elderly women provided blood for comprehensive > evaluation of iron status and cell-mediated and innate immunity. Women were classified > as iron-deficient or iron-sufficient on the basis of multiple abnormal iron status test > results. Groups were compared with respect to lymphocyte subsets, phagocytosis, > oxidative burst capacity, and T cell proliferation upon stimulation with mitogens. > > RESULTS: In iron-deficient women, T cell proliferation upon stimulation with concanavalin > A and phytohemagglutinin A was only 40-50% of that in iron-sufficient women. > Phagocytosis did not differ significantly between the 2 groups, but respiratory burst was > significantly less (by 28%) in iron-deficient women than in iron-sufficient women. > > CONCLUSIONS: Iron deficiency is associated with impairments in cell-mediated and innate > immunity and may render older adults more vulnerable to infections. Further prospective > studies using similar exclusion criteria for disease, infection, and concomitant nutrient > deficiencies are needed for simultaneous examination of the effects of iron deficiency on > immune response and morbidity. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 16, 2007 Report Share Posted August 16, 2007 In a message dated 8/16/2007 3:09:14 PM Eastern Daylight Time, janel@... writes: Mine was 7, I win! Nelly LOLOLOL!!!!!!!!!! Get a sneak peek of the all-new AOL.com. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 16, 2007 Report Share Posted August 16, 2007 Personally, if you feel better when you take iron, then I'd say take iron. That's about the only thing we've really got going for us. Every thing else is pretty much theory, and theories change with the direction of the wind. penny kdrbrill <kdrbrill@...> wrote: Hi Penny,Haven't had a ferritin test in awhile -- think the last one was 53-ish or so -- kind of the low-end of "normal". Wish I could afford that spectra-cell testing...I just know that in the past -- whenever I've taken iron -- along with other co-factors (Very important as you say) -- I've "recovered", at least for 9 months to a year or so. But I've been spooked into worrying that it might worsen things...so am more cautious lately.I did the testing as well -- probably four years ago. I was okay in most things exceept trace minerals (almost absent) and my potassium was HIGH, sodium very low. Worn out adrenals, they said..................?d> Not on CFS patients, but...interesting...> > 1: Am J Clin Nutr. 2004 Mar;79(3):516-21.Click here to read Links> Immune function is impaired in iron-deficient, homebound, older women.> Ahluwalia N, Sun J, Krause D, Mastro A, Handte G.> > Department of Nutritional Sciences, The Pennsylvania State University, University Park, > PA 16802, USA.> > BACKGROUND: Aging is often associated with a dysregulation of immune function. Iron > deficiency may further impair immunity in older adults. Published reports on iron > deficiency and immune response in humans are inconsistent. Most studies are focused on > young children in developing countries and are often confounded by comorbid conditions, > infections, and nutrient deficiencies. > > OBJECTIVE: Our objective was to determine the relation of iron status with immune > function in homebound older women, who often have impairments in both iron status and > immune response. The subjects were selected according to rigorous exclusion criteria for > disease, infection, and deficiencies in key nutrients known to affect immunocompetence. > > DESIGN: Seventy-two homebound elderly women provided blood for comprehensive > evaluation of iron status and cell-mediated and innate immunity. Women were classified > as iron-deficient or iron-sufficient on the basis of multiple abnormal iron status test > results. Groups were compared with respect to lymphocyte subsets, phagocytosis, > oxidative burst capacity, and T cell proliferation upon stimulation with mitogens. > > RESULTS: In iron-deficient women, T cell proliferation upon stimulation with concanavalin > A and phytohemagglutinin A was only 40-50% of that in iron-sufficient women. > Phagocytosis did not differ significantly between the 2 groups, but respiratory burst was > significantly less (by 28%) in iron-deficient women than in iron-sufficient women. > > CONCLUSIONS: Iron deficiency is associated with impairments in cell-mediated and innate > immunity and may render older adults more vulnerable to infections. Further prospective > studies using similar exclusion criteria for disease, infection, and concomitant nutrient > deficiencies are needed for simultaneous examination of the effects of iron deficiency on > immune response and morbidity.> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 16, 2007 Report Share Posted August 16, 2007 Mine was 7, I win! Nelly Re: [infections] Re: STUDY: Iron and Immune Function WOW! Your ferratin was 53???? Mine was 8 at one point! Crap! LOL! But, now I've had endometrial ablation and I find out next Thursday what my ferratin is up to now. I also have MS, so I'm wondering about the Immune issue. KLS Get a sneak peek of the all-new AOL.com. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 16, 2007 Report Share Posted August 16, 2007 Nice to see you have a sense of humor about it Nelly! I think that's what's kept me going too, despite the negatives. Here's a link from Medline that shows how ridiculously wide the " normal " range is for ferritin, and reiterates " The lower the ferritin level, even within the " normal " range, the more likely it is that the patient does not have enough iron. " http://www.nlm.nih.gov/medlineplus/ency/article/003490.htm I'd like to try and get mine up to say 100, but will have it checked first, as I have an appt w/my medicaid (non)-doctor tomorrow... Dan --- In infections , " Nelly Pointis " <janel@...> wrote: > > Mine was 7, I win! > > Nelly > Re: [infections] Re: STUDY: Iron and Immune Function > > > WOW! Your ferratin was 53???? Mine was 8 at one point! Crap! LOL! But, now I've had endometrial ablation and I find out next Thursday what my ferratin is up to now. I also have MS, so I'm wondering about the Immune issue. > > KLS > > > > > > ---------------------------------------------------------------------------- -- > Get a sneak peek of the all-new AOL.com. > Quote Link to comment Share on other sites More sharing options...
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