Re: Hormones- Nelly

[Guest guest]

Barb,

Thanks for this.

I tried to send you a mail but it bounces. Any suggestions as to where I can re-send it ?

Nelly

[infections] Hormones- Nelly

Nelly:I used ZRTLABS- and my ALT DR. uses them also.. although you don't need a Doc.. they'll send you the kit. Do all 8 hormones.Probably from my genetics- I have a fairly high Estrone - even without HRT.. but I had a compounding pharmacy whip up my bioidentical creams (appied to the skin)to balance my hormones.(Small dose 2.5 mg every 3 days of DHEA by mouth)www.zrtlab.comHere's some references.Barb#1 DHEA and Estrone1: Clin Calcium. 2003 Nov;13(11):1419-24.Links[DHEA and bone metabolism][Article in Japanese]Yanase T, Suzuki S, Goto K, Nawata H, Takayanagi R.Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University.A strong positive correlation of serum dehydroepiandrosterone sulfate (DHEA-S) and estrone (E1) with bone mineral density (BMD) in postmenopausal women but no correlation between serum estradiol (E2) and BMD in the same group suggest that circulating adrenal androgen may be converted to estrogen in peripheral tissues including osteoblast and may contribute to BMD maintenance. Actually, in cultured human osteoblast cells, DHEA can be converted to androstenedione and then androstenedione to estrone through the apparent aromatase activity. In human bone cells, intracrine mechanism through aromatase activity may contribute to the local production of estrogens, thus leading to protective effect against osteoporosis especially after menopause.PMID: 15775227 [PubMed]2: ESTRIOL1: J Gerontol A Biol Sci Med Sci. 2000 Apr;55(4):B183-90; discussion B191-3. LinksEstriol (E3) replacement improves endothelial function and bone mineral density in very elderly women.Hayashi T, Ito I, Kano H, Endo H, Iguchi A.Department of Geriatrics, Nagoya University School of Medicine, Japan. hayashi@...We investigated the effects of estriol (E3) on endothelial function and bone mineral density (BMD) in very elderly women. Twenty-four very elderly women (80 +/- 3.5 years old) were administered CaCl2 with or without estriol treatment (2 mg/day) for 30 weeks (hormone replacement treatment [hrT] group vs control group). Endothelium-dependent flow-mediated dilatation (FMD), endothelium-independent dilatation by nitroglycerin of the brachial artery, and BMD were assessed. Levels of plasma lipids and apoproteins were not changed; however, both plasma E3 and E2 were substantially increased (E2, 4.6 to 31.3 +/- 8.1; E3, <5 to 45.3 +/- 7.9 pg/mL) by HRT. The FMD value was also increased by HRT, as were the plasma nitrite/nitrate and cGMP values. The response to nitroglycerin was not changed. The BMD was increased by HRT, but decreased in the control group. There were significant differences between the HRT group and control group after 30 weeks' treatment in the levels of osteocalcin, P1CP, and urinary deoxypiridinoridine. E3 significantly improved BMD by inhibiting bone resorption. Endothelial function was improved in line with the antiatherosclerotic effects. E3 might be effective for use in HRT in elderly patients.PMID: 10811145 [PubMed - indexed for MEDLINE]