Hormones- Nelly

[Guest guest]

Nelly:

I used ZRTLABS- and my ALT DR. uses them also.. although you don't

need a Doc.. they'll send you the kit. Do all 8 hormones.

Probably from my genetics- I have a fairly high Estrone - even

without HRT..

but I had a compounding pharmacy whip up my bioidentical creams

(appied to the skin)to balance my hormones.(Small dose 2.5 mg every 3

days of DHEA by mouth)

www.zrtlab.com

Here's some references.

Barb

#1 DHEA and Estrone

1: Clin Calcium. 2003 Nov;13(11):1419-24.Links

[DHEA and bone metabolism][Article in Japanese]

Yanase T, Suzuki S, Goto K, Nawata H, Takayanagi R.

Department of Medicine and Bioregulatory Science, Graduate School of

Medical Sciences, Kyushu University.

A strong positive correlation of serum dehydroepiandrosterone sulfate

(DHEA-S) and estrone (E1) with bone mineral density (BMD) in

postmenopausal women but no correlation between serum estradiol (E2)

and BMD in the same group suggest that circulating adrenal androgen

may be converted to estrogen in peripheral tissues including

osteoblast and may contribute to BMD maintenance. Actually, in

cultured human osteoblast cells, DHEA can be converted to

androstenedione and then androstenedione to estrone through the

apparent aromatase activity. In human bone cells, intracrine

mechanism through aromatase activity may contribute to the local

production of estrogens, thus leading to protective effect against

osteoporosis especially after menopause.

PMID: 15775227 [PubMed]

2: ESTRIOL

1: J Gerontol A Biol Sci Med Sci. 2000 Apr;55(4):B183-90; discussion

B191-3. Links

Estriol (E3) replacement improves endothelial function and bone

mineral density in very elderly women.Hayashi T, Ito I, Kano H, Endo

H, Iguchi A.

Department of Geriatrics, Nagoya University School of Medicine,

Japan. hayashi@...

We investigated the effects of estriol (E3) on endothelial function

and bone mineral density (BMD) in very elderly women. Twenty-four

very elderly women (80 +/- 3.5 years old) were administered CaCl2

with or without estriol treatment (2 mg/day) for 30 weeks (hormone

replacement treatment [hrT] group vs control group). Endothelium-

dependent flow-mediated dilatation (FMD), endothelium-independent

dilatation by nitroglycerin of the brachial artery, and BMD were

assessed. Levels of plasma lipids and apoproteins were not changed;

however, both plasma E3 and E2 were substantially increased (E2, 4.6

to 31.3 +/- 8.1; E3, <5 to 45.3 +/- 7.9 pg/mL) by HRT. The FMD value

was also increased by HRT, as were the plasma nitrite/nitrate and

cGMP values. The response to nitroglycerin was not changed. The BMD

was increased by HRT, but decreased in the control group. There were

significant differences between the HRT group and control group after

30 weeks' treatment in the levels of osteocalcin, P1CP, and urinary

deoxypiridinoridine. E3 significantly improved BMD by inhibiting bone

resorption. Endothelial function was improved in line with the

antiatherosclerotic effects. E3 might be effective for use in HRT in

elderly patients.

PMID: 10811145 [PubMed - indexed for MEDLINE]