Guest guest Posted September 1, 2008 Report Share Posted September 1, 2008 > > which is a type of autoimmune disease > haven't we all heard the AI theories > > Cpn is no AI disease. Lots of people in our spheres think AI is some kind of hoax, but it ain't so. AI's not even a theory, really. At least some of the antibody-mediated AI diseases feature totally uncontroversial AI, demonstrated by pretty dang clear experiments, such as serum transfer to mice, or serum transfer to tissue explants (such as a chunk of thyroid saved from a dead dude, a thyroidectomy, or an animal). Graves' disease, pemphigus, and Myasthenia gravis are in this set of diseases with clearly symptomogenic antibodies. I may be leaving some out. Lupus I'm not sure about. I will admit I haven't scrutinized the methods of these findings myself. Non-antibody-mediated symptomogenic AI has been way harder to show, in man. It's easy to show in animals on which wicked experiments are allowed. Most people take this for significant evidence that similar results would be found in man. I am not yet sure what I think about that. Also, it's very true that calling them AI diseases is problematic. This is just like the term " mental illness " -- which on one level, is totally accurate, but is totally misleading on another level. Obviously any given AI /could/ be caused by a chronic infection for all we know and could potentially be curable by eliminating infection. Actually it is /always/ problematic to come up with a term characterizing a disease or set of diseases, if we don't have a clue about its headwaters, although " mental illness " is probably the worst specimen. It's like trying to describe a novel object when a portion of it is shrouded -- you don't even know how much is hidden, let alone /what/ is hidden. Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.