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Re: Cipro/flouroquinolone drugs: FDA calls fo...

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Hi, Penny.

Thanks for the plug!

Jay Cohen's website reports the experience of one guy with

fluoroquinolone damage who benefited from IV glutathione:

http://www.medicationsense.com

There are actually some pretty interesting papers in the literature,

accessible free at PubMed, that make the case that the damage

mechanism of the fluoroquinolones is the production of reactive

oxygen species and depletion of glutathione. PMID: 14569066 is one

about tendon damage. PMID: 16495256 shows that the same mechanism is

used by the fluoroquinolones to kill bacteria. There's another that

shows the same mechanism produces liver and brain damage in mice at

high doses of fluoroquinolones.

I used to encourage PWCs with fluoroquinolone damage to try

magnesium, too, and some found it helped them. There may be a

connection between Mg and glutathione in CFS. There's a paper in the

literature that shows that in red blood cells, if glutathione is low,

the cells cannot maintain normal levels of intracellular Mg.

I think this glutathione connection can explain why PWCs seem to be

particularly vulnerable to damage from fluoroquinolones. Many or

most are already depleted in glutathione. We're getting more data on

that now using the Vitamin Diagnostics methylation panel, which

includes measurements of serum reduced and oxidized glutathione.

Rich

>

> I don't think glutathione can hurt you. I think the problem is

absorbing it to begin with. I did i.v. glutathione and really didn't

notice any change, but others claim to be benefitting from it in

other forms. Rich V. is the expert on that. If you do a search at the

I & I home site for rvankonynen, you'll find a lot of stuff from him.

>  

> penny

>

> --- On Mon, 7/14/08, ThunderLungsABA@... <ThunderLungsABA@...>

wrote:

>

> From: ThunderLungsABA@... <ThunderLungsABA@...>

> Subject: Re: [infections] Re: Cipro/flouroquinolone

drugs: FDA calls fo...

> infections

> Date: Monday, July 14, 2008, 7:17 PM

>

>

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>

>

>

>

>

> In a message dated 7/14/2008 8:19:56 PM Eastern Daylight Time,

pennyhoule (DOT) com writes:

>

> Yeah, I do know a lot of people have been affected. Probably a

whole lot for the FDA to go public. I wonder, though, if people had

been told about magnesium perhaps some would have had a chance to

avoid serious injury?

>

> penny 

>

> Yeah. We do take magnesium and we just found out about a therapy

that works - glutathione. Although I want to make sure this is safe

and won't cause other problems.

>  

> KLS 

>

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